Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Multi Immersion Microscope Captures Rapid 3D Dynamics in Living Cells

An international team of researchers led by UT Southwestern Medical Center has developed a versatile light-sheet microscope that captures 3D views of biological samples, from activity inside living cells to larger tissues.

6 Nov 2026

Microgravity Drives the Metabolic Switch From Glycolysis to Oxidative Phosphorylation

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

4 Nov 2026

Cedars-Sinai Expands Stem Cell Research Aboard the Space Station

When NASA’s SpaceX CRS-35 mission docks with the International Space Station Oct. 15, it will deliver two experiments from the Cedars-Sinai Center for Space Medicine Research.

16 Oct 2026

Intestinal Cells Use Signal Rhythms to Determine Cell Growth

A study conducted at the Hubrecht Institute reveals that the intestines use the rhythm of a signal to decide which cells to make.

16 Oct 2026

Cell Division Actively Reshapes Crowded Epithelial Tissue, Study

Every time a tissue grows or renews itself, cells must divide inside an already crowded environment.

16 Oct 2026

Immunometabolic Reprogramming Strategy Addresses Chronic Inflammatory Conditions

Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.

16 Oct 2026

Mount Sinai Launches Bioengineered Brain and Heart Models Into Space

Mount Sinai researchers are sending bioengineered human brain and cardiovascular tissue models into space for the first time today, as part of the SpaceX CRS-35 mission, to study brain activity, cardiovascular function, and accelerated aging in orbit.

15 Oct 2026

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor's cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.

10 Oct 2026

Engineered Biological Bandages Utilize Human Epicardial Cells for Heart Repair

Researchers have discovered a new cell type that may help regulate blood vessel growth in the heart during development and in response to injury, according to a study from Weill Cornell Medicine. Working with zebrafish, they found that the new cell type helps stabilize the vascular network that supplies oxygen to growing cardiac muscle.

5 Oct 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Antiretroviral drugs let people with HIV live full-length lives, but cognitive problems often persist. Some studies have found cognitive impairment in as many as half of people receiving antiretroviral therapy, although estimates vary and many cases do not interfere with daily activities.

24 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Stem cell researchers have identified inflammatory pathways that may play a key role in driving kidney damage in diabetic kidney disease (DKD), pointing to potential new approaches for protecting the kidneys.

18 Sep 2026

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Stanford Medicine scientists have chalked up a major advance in growing human brain cells outside of the human brain - and outside of laboratory glassware.

17 Sep 2026

Advanced Diagnostic Technologies Target Inaccessible Plasma Cells Housed inside Bones

For decades, immunologists have known that the body's most durable defenses depend on plasma cells, the antibody-producing cells responsible for long-term immune memory.

15 Sep 2026

Scientists Discover How Elusive Brain Stem Cells Make Decisions

As the human brain takes shape before birth, a remarkable type of stem cell helps give it many of the features that make it distinctly human.

7 Sep 2026

Bacterial Chemical Signals Work Together to Control Intestinal Movement

Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement.

3 Sep 2026

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

When you add drops of oil to water, the oil and water remain separate. Within cells, biological molecules cluster together in a similar way, separating themselves from the rest of the cell. And while they don't have a membrane, they are their own distinct compartments.

3 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

31 Aug 2026