Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Microglia Found to Drive New Neuron Growth in Adult Hippocampus

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

10 Feb 2026

Revvity Unveils New High-Impact Discovery Platforms and Showcases Recent Innovations at SLAS2026

Revvity, Inc. announced the launch of multiple new discovery platforms and technologies at SLAS2026, which are designed to accelerate high-throughput drug discovery workflows.

5 Feb 2026

Autism-Linked Mutations Converge on Shared Early Brain Pathways

UCLA Health researchers have created a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development, providing new insights into the ways diverse genetic causes may lead to shared features and symptoms of the disorder.

29 Jan 2026

Advanced 3D Tumor Organoids Reveal How Glioblastoma Responds to Immunotherapy

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

28 Jan 2026

Scientists Uncover How Cell Growth and Pressure Shape Pancreatic Ducts

Researchers discovered that pressure and cell division rate influence the form of fluid-filled cavities in the developing pancreas.

12 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

24 Dec 2025

Senescent Fibroblasts in the Tumor Niche Rewire Lung Cancer Metabolism and Plasticity

Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone by since cell biologist Judith Campisi, PhD, paradoxically demonstrated that these same cells can promote cancer growth in a laboratory setting.

5 Dec 2025

Advancing Brain Research With Nanowire-Based Astrocyte Models

Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.

25 Nov 2025

Innovative Human Cell Model Shows How Melanoma Thrives in the Brain

Using human cells and cutting-edge technology, the team created a three-dimensional (3D) model that accurately simulates the brain invaded by aggressive cancer.

19 Nov 2025

Bone Regeneration Breakthrough: Next-Gen Nanoparticle-Stem Cell Hybrids Show Promise

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

13 Nov 2025

Transforming Stomach Cells into Insulin Factories for Diabetes Treatment

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide.

7 Nov 2025

Muscle Tissue from a 3D Printer – Produced in Zero Gravity

On their way into space, astronauts' bodies deteriorate dramatically in zero gravity. To address this problem and protect our pioneers in space, researchers are looking for realistic test models.

7 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025

Electromagnetic Levitation Enables Noninvasive Sorting of Cancer and Healthy Cells

Stanford Medicine researchers invent an electromagnetic device that can gently sort different types of cells by levitating them to different heights.

28 Oct 2025

Human Kidney Organoids Offer New Insights into APOL1-Mediated Kidney Disease

Chronic kidney disease (CKD) impacts over 700 million individuals globally and arises from a combination of genetic and environmental influences, along with pre-existing health conditions.

3 Oct 2025

Study Identifies a Cellular Mechanism That Alters the Gut Microbiome

It is well established that gut microbiome composition plays a pivotal role in human health – yet the precise connections are still not fully elucidated.

24 Sep 2025

USC Researchers Advance Toward Building Functional Synthetic Kidneys

A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.

18 Sep 2025

Intestinal Cells Pull Rather Than Push to Remove Weaker Neighbors

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In a recent publication in the journal Science, researchers of the Hubrecht Institute and AMOLF show that this is not correct.

4 Sep 2025