Organoids News and Research

RSS

Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Antiretroviral drugs let people with HIV live full-length lives, but cognitive problems often persist. Some studies have found cognitive impairment in as many as half of people receiving antiretroviral therapy, although estimates vary and many cases do not interfere with daily activities.

24 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Stem cell researchers have identified inflammatory pathways that may play a key role in driving kidney damage in diabetic kidney disease (DKD), pointing to potential new approaches for protecting the kidneys.

18 Sep 2026

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Stanford Medicine scientists have chalked up a major advance in growing human brain cells outside of the human brain - and outside of laboratory glassware.

17 Sep 2026

Advanced Diagnostic Technologies Target Inaccessible Plasma Cells Housed inside Bones

For decades, immunologists have known that the body's most durable defenses depend on plasma cells, the antibody-producing cells responsible for long-term immune memory.

15 Sep 2026

Scientists Discover How Elusive Brain Stem Cells Make Decisions

As the human brain takes shape before birth, a remarkable type of stem cell helps give it many of the features that make it distinctly human.

7 Sep 2026

Bacterial Chemical Signals Work Together to Control Intestinal Movement

Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement.

3 Sep 2026

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

When you add drops of oil to water, the oil and water remain separate. Within cells, biological molecules cluster together in a similar way, separating themselves from the rest of the cell. And while they don't have a membrane, they are their own distinct compartments.

3 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

31 Aug 2026

Researchers Identify Early Molecular Warning Signs of Inflammatory Bowel Disease

Researchers have uncovered early molecular warning signs of inflammatory bowel disease, revealing the condition can begin before symptoms appear and continue silently even when patients appear well.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 29 Aug 2026

Primate-Specific DNA Change Reveals a New Link to Dementia-Related Neurodegeneration

29 Aug 2026

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach with the potential to treat a wide range of genetic diseases that share certain disease-causing mutations.

28 Aug 2026

Scientists Give Lab-Grown Brain Organoids a Regional Biological Compass

The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it's organized.

21 Aug 2026

Tireless Stem Cells Drive Continuous Renewal Across High Friction Human Intestines

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells. These stem cells can both replace the various types of intestinal cells that have been lost as well as renew themselves.

6 Aug 2026

Kobe University Unveils Mass-Producible Off-the-Shelf Cancer Fighters

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

24 Jul 2026

Synthetic Organizer Cells To Build More Realistic Kidney Organoids

In research published in Science, USC researchers combined a biological finding with an engineering achievement to produce organoids—lab-grown kidney structures derived from stem cells—that are more faithful and reproducible.

3 Jul 2026

Stanford Researchers Find Dual Protein Mechanism Driving Psoriasis Inflammation

Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found.

26 Jun 2026

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

23 Jun 2026

Organoids News and Research

Further Reading

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Advanced Diagnostic Technologies Target Inaccessible Plasma Cells Housed inside Bones

Scientists Discover How Elusive Brain Stem Cells Make Decisions

Bacterial Chemical Signals Work Together to Control Intestinal Movement

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Researchers Identify Early Molecular Warning Signs of Inflammatory Bowel Disease

Primate-Specific DNA Change Reveals a New Link to Dementia-Related Neurodegeneration

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

Scientists Give Lab-Grown Brain Organoids a Regional Biological Compass

Tireless Stem Cells Drive Continuous Renewal Across High Friction Human Intestines

Kobe University Unveils Mass-Producible Off-the-Shelf Cancer Fighters

Synthetic Organizer Cells To Build More Realistic Kidney Organoids

Stanford Researchers Find Dual Protein Mechanism Driving Psoriasis Inflammation

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

eBook: Essential Guide to Organoids for Drug Discovery Applications eBook

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

Latest in Genomics