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Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Cell Phase Separation Creates Droplets That Optimize and Activate Kinase Signaling

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a phenomenon known as phase separation.

2 Jun 2026

OIST Scientists Uncover Key Mechanism Behind Regulated Cell Division

During animal cell division, a highly synchronized and tightly regulated dance of chromosomes takes place, ensuring the chromosomes split correctly into the two cells.

28 May 2026

New Discovery Reveals How HIV Infects Resting Immune Cells

Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells.

7 May 2026

'Spiderman' Cells Trap Viral Genomes With Sticky Protein Webs

Scientists have identified a cell defense mechanism that mimics Spiderman shooting his web to ensnare enemies.

18 Mar 2026

Discovery of Nuclear Metabolic Fingerprints Offers New Insights Into Cancer

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.

9 Mar 2026

Blood Tau217 Test Predicts When Alzheimer’s Symptoms May Begin

The %p-tau217 biomarker in blood offers a novel approach to estimate Alzheimer's onset, potentially transforming prevention trial strategies.

5 Mar 2026

Brain Enzymes MNK1 and MNK2 Regulate Distinct Behaviors in the Brain

Researchers at the Max Delbrück Center show that two related enzymes, MNK1 and MNK2, act on the brain to regulate different behaviors.

20 Feb 2026

Single-cell atlas reveals how melanoma evades the immune system

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

11 Feb 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026

Elusive Kinase State Explains How Cells Achieve Efficient Signaling

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its target, without needing to release

19 Dec 2025

Kefir-Derived Bacteria Show Potential to Reverse Age-Related Immune Decline

The process of aging is associated with a decline in immune functions and persistent low-level inflammation.

18 Dec 2025

Researchers Uncover How Methamphetamine Suppresses Dopamine Clearance

Dopamine brings on a surge of pleasure, but too much dopamine in a synapse can ultimately lead to mood disorders and addiction.

26 Nov 2025

Comprehensive Kinase Atlas Redefines Regulation of Gene Transcription Machinery

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

St. Jude Researchers Uncover Dual Role of ASPL in Stress Granule Assembly and Disassembly

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

10 Oct 2025

Aurora A Enzyme Guides Proper Nuclear Formation in Dividing Cells

Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic material (chromosomes) equally, and then rebuild the nuclear envelope around the separated halves.

24 Sep 2025

Molecular Fossils Offer Fresh Insights into the Dawn of Biology

The questions of how humankind came to be, and whether we are alone in the universe, have captured imaginations for millennia. But to answer these questions, scientists must first understand life itself and how it could have arisen.

24 Sep 2025

First Complete Map of Plant Stress Response System Unveiled

Researchers have created the world's first complete map of a crucial cellular system that helps plants respond to stress.

4 Sep 2025

New Insights into Cell Membrane Energy Waves

Johns Hopkins researchers identify energy-generating waves on cancer cell membranes, revealing potential targets for slowing tumor growth and spread.

9 Jul 2025

Combating Tumor Resistance and Exhaustion in Lymphoma

The study reviews CAR-T cell advancements in lymphoma treatment, addressing T cell exhaustion and tumor immune evasion with next-generation CAR modifications.

24 Jun 2025