Phosphorylation News and Research

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Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Research Maps Structural Mechanism Linking Amino Acid Availability to Cancer Growth

Cells carry their own growth switches. When enough nutrients-amino acids in particular-are available, cells flip this switch on and begin to grow. Researchers at KAIST and Yonsei University have now uncovered the molecular mechanism by which amino acid signals activate this cellular growth switch.

27 Jul 2026

Research Maps Structural Interactions Between Mitochondria and Lipid Droplets

An international study by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the University of California, Los Angeles (UCLA) has identified a fundamental mechanism that regulates how the body uses stored fat to produce energy.

10 Jul 2026

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance. The tumor microenvironment and the gut microbiome are increasingly recognized as critical determinants of immunotherapy outcomes.

2 Jul 2026

New Evolutionary Framework Views Psychedelic Compounds as Crucial Ecological Tools

Natural hallucinogens, such as psilocybin, mescaline, N,N-dimethyltryptamine (DMT), and related compounds, have generally received attention for their effects on human perception, emotion, and cognition.

25 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Cell Phase Separation Creates Droplets That Optimize and Activate Kinase Signaling

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a phenomenon known as phase separation.

2 Jun 2026

OIST Scientists Uncover Key Mechanism Behind Regulated Cell Division

During animal cell division, a highly synchronized and tightly regulated dance of chromosomes takes place, ensuring the chromosomes split correctly into the two cells.

28 May 2026

New Discovery Reveals How HIV Infects Resting Immune Cells

Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells.

7 May 2026

'Spiderman' Cells Trap Viral Genomes With Sticky Protein Webs

Scientists have identified a cell defense mechanism that mimics Spiderman shooting his web to ensnare enemies.

18 Mar 2026

Discovery of Nuclear Metabolic Fingerprints Offers New Insights Into Cancer

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.

9 Mar 2026

Blood Tau217 Test Predicts When Alzheimer’s Symptoms May Begin

The %p-tau217 biomarker in blood offers a novel approach to estimate Alzheimer's onset, potentially transforming prevention trial strategies.

5 Mar 2026

Brain Enzymes MNK1 and MNK2 Regulate Distinct Behaviors in the Brain

Researchers at the Max Delbrück Center show that two related enzymes, MNK1 and MNK2, act on the brain to regulate different behaviors.

20 Feb 2026

Single-cell atlas reveals how melanoma evades the immune system

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

11 Feb 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026