Polymerase News and Research

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Painkillers reduce electric shock escape behaviour in lobsters

Analgesic treatments in Norway lobsters show promise in reducing shock responses, emphasizing the need for humane practices in crustacean research and industry.

23 Apr 2026

Epigenetic Regulators Shape Gene Activity in Unexpected Ways

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off.

21 Apr 2026

Redefining Cancer Therapy Through Selective Targeting of BET Protein Families

For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations.

10 Apr 2026

Breakthrough Platform Could Accelerate Therapeutic Development for Mitochondrial Disorders

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

7 Apr 2026

Study Reveals How Biological Machines Write New Genetic Information

New research has discovered that the molecular machines responsible for copying our DNA have a surprising hidden talent – an ability to create entirely new and highly sophisticated DNA sequences from scratch.

1 Apr 2026

Newly Discovered CRISPR System Activates Genes Without Cutting DNA

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA.

26 Mar 2026

New Cell-Free Method Reveals Hidden Rules of Bacterial Gene Expression

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.

5 Mar 2026

Engineered E. coli Produces Key Plant Compound at Record Levels

Researchers engineered E. coli to produce orsellinic acid-derived meroterpenoids, offering a sustainable alternative to traditional plant extraction methods.

25 Feb 2026

Hutton Scientists Develop New Test for Fecal Contamination Which Cuts Time for Results From 24 Hours to Four

Scientists at The James Hutton Institute, Scotland’s pre-eminent interdisciplinary scientific research institute for the sustainable management of land, crop and nature resources, have developed a new test that reduces the time required to analyze water samples for indicators of fecal contamination from 24 hours to four.

24 Feb 2026

Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parathyroid hormone shows promise in treating low back pain by remodeling degenerating vertebral endplates and limiting pathological sensory innervation.

12 Feb 2026

Single-cell atlas reveals how melanoma evades the immune system

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

11 Feb 2026

Powerful New Enzyme Efficiently Synthesizes RNA

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine.

10 Feb 2026

New Research Reveals RFC's Dynamic Partnership in DNA Synthesis

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its code and build new strands.

2 Feb 2026

Cryo-EM Uncovers Alarmone-Driven RNA Transcription Initiation

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated.

31 Jan 2026

Visualizing Real-Time DNA Transcription in a Living Mouse

DNA can be regarded as an extensive library that contains all genetic information. Cells do not utilize this information simultaneously.

30 Jan 2026

Blood protein test helps spot hidden cancers in patients with vague symptoms

Plasma protein profiling offers a promising tool for cancer risk stratification in patients with non-specific symptoms, potentially reducing diagnostic delays.

28 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

Syntax Bio Develops CRISPR Technology to Program Stem Cell Gene Activity

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm™ technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

8 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025