Polymerase News and Research

RSS

Powerful Imaging Technique Captures Gene Transcription Inside Living Organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

21 Aug 2026

Molecular Motors Driven by Chemical Energy Construct Active DNA Architectures

Drawing inspiration from the dynamic architecture of living systems, researchers from Institute of Science Tokyo and Kyoto University have harnessed two chemically fueled biomolecular nanomachines, DNA polymerase and kinesin, to synthesize and actively assemble complex, hierarchical DNA networks.

20 Aug 2026

New Chromosome-Level Pangenome Graph Maps Apricot's Genetic Diversity

Cultivated apricot, Prunus armeniaca, emerged through at least two domestication routes from Central Asia before spreading toward China and the Mediterranean.

17 Aug 2026

Study Shows How Compact Viral Structures Boost Protein Yields for mRNA Vaccines

A research team led by Director KIM V. Narry at the Center for RNA Research within the Institute for Basic Science (IBS) has discovered compact viral RNA elements that can make mRNA more stable and increase protein production.

17 Aug 2026

Mapping Functional Polyprotein Cleavage Sites Solves Post Infection Testing Dilemmas

Current coronavirus diagnostics mainly rely on nucleic acid amplification, antibody detection, or viral antigen detection.

17 Aug 2026

ORBIT Technology Leverages DNA Origami for Next-Generation Biological Discovery

Scientists often describe life as a series of chemical reactions. Pallav Kosuri, PhD, describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells, and bodies-without movement, there is no life.

14 Aug 2026

Novel Approach Provides a Flexible Foundation for Measuring Coronavirus Protease Activity

A research team has computationally designed a synthetic peptide that enables modular detection of the enzymatic activity of coronavirus 3C-like protease (3CLPro), an enzyme essential for viral replication and maturation.

13 Aug 2026

Study Reveals Previously Unknown Mechanism of RNA Synthesis Shared Across Life Forms

Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP).

13 Aug 2026

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Cells can switch off genes by tightly packaging DNA around proteins called histones.

6 Aug 2026

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

Next-Generation Biosensing Shows How Bacteriophages Revolutionize Bacterial Disease Detection

Pathogenic bacteria remain a persistent threat to public health, food supplies, and water systems, particularly as antimicrobial resistance makes infections increasingly difficult to treat.

11 Jul 2026

A New Non-Destructive Tool Maps Active Transcription Profiles in Living Tissue

Cell function is determined by how DNA is expressed into proteins. That process includes two main steps - transcription, when messenger RNA (mRNA) makes copies of active genes, and translation, when mRNA guides protein assembly.

2 Jun 2026

Rapid Diagnostic Tool Yields Definitive Bacterial Pathogen Screening Results in 40 Minutes Flat

Inspired by the widely used and user-friendly COVID-19 strip test kits, a team of science students from Chulalongkorn University has developed a test kit for detecting pathogens in milk and dairy products. The team combined the LAMP technique with strip test technology to create a simple screening tool for harmful bacteria that can be easily used by the public.

26 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Metabolic Pathway Loss Makes Cancer Cells Vulnerable to PARP Drugs

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

5 May 2026

Engineered Bacteriophage Speeds up the "Training" of Plastic-Eating Bacteria

Millions of tons of plastic waste build up in landfills and oceans each year. One promising approach is to engineer microbes to break plastic down into useful chemical building blocks.

4 May 2026

Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk

The study identifies PRRX1 as a critical factor in breast cancer metastasis, highlighting its potential as a biomarker for predicting aggressive disease.

29 Apr 2026

New DNA Tests Expose Spice Fraud Across Popular Herbs and Spices

Researchers interlaboratory-validated 13 DNA-based qPCR methods to quantify selected plant adulterants in paprika/chilli, saffron, turmeric, cumin, oregano, and black pepper. The methods showed strong repeatability, reproducibility, and trueness, supporting their use as confirmatory tools in official spice authenticity testing.

28 Apr 2026

Painkillers reduce electric shock escape behaviour in lobsters

Analgesic treatments in Norway lobsters show promise in reducing shock responses, emphasizing the need for humane practices in crustacean research and industry.

23 Apr 2026