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Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parathyroid hormone shows promise in treating low back pain by remodeling degenerating vertebral endplates and limiting pathological sensory innervation.

12 Feb 2026

Fruit Fly Study Reveals How Mating Triggers Behavioral Changes in Females

Researchers from The Universities of Manchester and Birmingham have identified the exact nerve cells in the brain that drive important behavioral changes in female fruit flies after they mate.

10 Feb 2026

New Genetic Rules Guide Killer T Cell Fate

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune cells-known as CD8 killer T cells-choose between becoming long-lasting, protective defenders or slipping into exhausted, dysfunctional states.

6 Feb 2026

Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

Postmortem Human Retinas Recover Neural Light Signals

The ability to restore light responses in human retinas postmortem offers a novel model for studying retinal recovery and developing vision-restoring therapies.

5 Feb 2026

Ancestry-Specific Genetic Models Advance Breast Cancer Risk Assessment

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry.

4 Feb 2026

Selective Mitophagy Enables Invasive Growth of Anthracnose Pathogen

Anthracnose is one of the most damaging fungal diseases affecting woody oil crops and many other plants, causing severe yield losses worldwide.

4 Feb 2026

Lower IgG Hinge Controls Antibody Assembly and Immune Function

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

31 Jan 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026

AI Decodes Evolutionary Programs Shaping the Mammalian Cerebellum

Artificial intelligence allows tracing the evolution of genetic control elements in the developing mammalian cerebellum.

31 Jan 2026

Decoding the Molecular Logic of Histamine Signaling in the Brain

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses.

19 Jan 2026

Unusual Antibody Tactics Hinder Pathogen Attachment to Cells

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

8 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026