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Automated 3D Imaging Uncovers Genetic Markers for Sorghum Leaf Arrangement

By reconstructing 366 sorghum plants from calibrated images, the team showed that automated measurements achieved near-human repeatability and enabled genome-wide association studies (GWAS) to uncover genetic markers linked to leaf orientation.

3 Sep 2025

Genetic On-Off Switch for Cilia Formation Uncovered

Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna. The technical name is primary cilium.

2 Sep 2025

Discovery of Dendritic Cell Reprogramming Opens Path to Tailored Cancer Treatments

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

2 Sep 2025

Muscle Reprogramming Protein Found to Both Activate and Repress Genes

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells.

11 Aug 2025

Study Reveals Hidden Function of So-Called Junk DNA

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression.

21 Jul 2025

Scientists Uncover How New Genes Are Switched On in Fruit Flies

Most genes are ancient and shared across species. But a small subset of genes are relative newcomers, spontaneously emerging from stretches of DNA that once encoded nothing at all.

14 Jul 2025

UAB Identifies Six Novel Subsets, Reshaping Immune Knowledge

The study highlights T-bet's importance in memory B cells, essential for rapid antibody production and sustained immune defense against influenza.

14 Jul 2025

Reinvigorating T Cells Offers Hope for More Effective Cancer Immunotherapy

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

8 Jul 2025

Newly Evolved Genes Found to Influence Human Cell Division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

24 Jun 2025

New Platform Technology Promises to Generate Hard-to-Get Human Cells

This study presents a fast method for generating human microglia from iPSCs, paving the way for breakthroughs in neurodegenerative disease research.

11 Jun 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025

Herpes Virus Protein Enhances T-Cell Survival for Cancer Therapy

Recent studies reveal the herpes virus may enhance cancer treatment by activating T cell pathways, improving immunotherapy effectiveness against tumors.

29 May 2025

RNA Editing and Transcriptional Switching Shape Fungal Antiviral Response

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems.

24 May 2025

AI Designs Synthetic DNA to Control Gene Expression in Mammalian Cells

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

10 May 2025

Study Unlocks Molecular Mechanisms Behind Tea Plant Defenses

Plants face constant threats from herbivores, prompting complex defense mechanisms. While grasses like rice and Arabidopsis have well-studied defense systems, woody plants like tea remain poorly understood.

7 May 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Guinea Pig Modeling To Study Human Preimplantation and Embryogenesis

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation stages and reproductive techniques.

23 Apr 2025

New Research Further Translates the Language of the Genome

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of human genes.

9 Apr 2025

UV Light Reshapes 3D Genome Structure, Altering DNA Repair and Gene Activity

Research shows UV radiation modifies 3D genome structure, affecting DNA damage response and gene activity, offering insights for cancer prevention strategies.

24 Mar 2025

Researchers Identify Promising Drug Candidates for Previously “undruggable” Cancer Target

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable” cancer protein target, permanently blocking it.

21 Mar 2025