Transcriptomics News and Research

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Mapping Diverse Brain Cell Populations Unlocks Deep Hidden Molecular Secrets

Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue.

22 Aug 2026

New Transcriptomic Framework Identifies Early Cell Damage Before Organ Failure

Researchers at the University of Cologne, University Hospital Cologne, and the Max Planck Institute for Metabolism Research have developed a method that, for the first time, enables damage to individual cells to be precisely quantified.

22 Aug 2026

Single-Cell Study Decodes Ancient Plant Partnership With Soil Fungi

Scientists at VIB and Ghent University have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi.

19 Aug 2026

High Resolution Imaging Exposes Root Causes of Chronic Heart Rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

13 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

New Research Reveals Cellular Switches Driving Physical Adaptation in Marine Species

In the animal kingdom, only those who adapt to their environment will survive. This adaptation comes in a wide range of forms, from invisible internal shifts in gene expression to dramatic anatomical changes, such as tadpoles growing legs and transitioning to life on land as frogs.

8 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Gut Microbiome Signatures Correlate With Clinical Efficacy in Immunotherapy Outcomes

Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.

9 Jul 2026

New Study Explains How Blood Cancer Cells Invade the Lungs

Led by NYU Langone Health researchers, a new study shows how blood cancer cells enter the lungs, damage tissue, and cause severe breathing problems.

30 Jun 2026

Advanced Bioinformatics Models Reveal Bacterial Function in Colon Cancer Patients

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

29 Jun 2026

Novel Cellular Discoveries Offer New Potential Treatment Strategies for Arthritis

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies.

25 Jun 2026

Advanced Bladder Cancer Spatial Mapping Identifies Diverse Cellular Tumor States

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic vulnerabilities are organized within tumors.

19 Jun 2026

Peking University Researchers Map High Dimensional Cellular Networks in Tumors

A comprehensive review led by Associate Researcher Linnan Zhu and Academician Zemin Zhang at Biomedical Pioneering Innovation Center (BIOPIC), Peking University, China, and Chongqing Medical University, China, was published in Volume 2, article number 27 of the journal Immunity & Inflammation on June 05, 2026.

13 Jun 2026

Scientists Identify Microglia Immune State Changes for Novel Alzheimer’s Therapies

Researchers from VIB, KU Leuven, the UK-DRI and Muna Therapeutics, funded by, among others, ERC, have uncovered a critical biological transition that may determine whether Alzheimer's disease pathology leads to dementia.

5 Jun 2026

Study Shows How AI and Single Cell Science are Changing Modern Medicine

Recent technological advances have pushed the boundaries of cellular biology far beyond what was conceivable even decades ago

4 Jun 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

A new study published in Engineering has established an absolute quantification strategy for immunoglobulin G (IgG) N-glycans linked to aging, providing a reliable method to assess biological age and explore anti-aging interventions.

15 May 2026

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

This study was led by Professor Yi Wang and Professor Weiming Zhu from the School of Medicine and Pharmacy, Ocean University of China.

15 May 2026

Transcriptomics News and Research

Mapping Diverse Brain Cell Populations Unlocks Deep Hidden Molecular Secrets

New Transcriptomic Framework Identifies Early Cell Damage Before Organ Failure

Single-Cell Study Decodes Ancient Plant Partnership With Soil Fungi

High Resolution Imaging Exposes Root Causes of Chronic Heart Rejection

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

New Research Reveals Cellular Switches Driving Physical Adaptation in Marine Species

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Gut Microbiome Signatures Correlate With Clinical Efficacy in Immunotherapy Outcomes

New Study Explains How Blood Cancer Cells Invade the Lungs

Advanced Bioinformatics Models Reveal Bacterial Function in Colon Cancer Patients

Novel Cellular Discoveries Offer New Potential Treatment Strategies for Arthritis

Advanced Bladder Cancer Spatial Mapping Identifies Diverse Cellular Tumor States

Peking University Researchers Map High Dimensional Cellular Networks in Tumors

Scientists Identify Microglia Immune State Changes for Novel Alzheimer’s Therapies

Study Shows How AI and Single Cell Science are Changing Modern Medicine

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

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