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New AI Model Decodes the Language of Immune Cell Movement

Researchers at The University of Texas MD Anderson Cancer Center and collaborating institutions in Texas developed an artificial intelligence (AI) model that helps explain how immune cells find their way to specific locations in the body and why they avoid others.

14 Oct 2026

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor's cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.

10 Oct 2026

Ancient Peptide Signals Shape Apple Root Regeneration

Apple production depends heavily on grafting, making rootstock traits central to water and nutrient uptake, stress resilience, and orchard performance.

9 Oct 2026

Integrated Multi-Omics Maps Metabolic Shift During Seed Development Stages

Canavalia gladiata, commonly known as sword bean, is a leguminous crop with high seed protein content (26%–30%) and oil rich in unsaturated fatty acids. Despite its nutritional promise, the species has remained underutilized, largely because a complete genome and the genetic basis of its nutritional traits were lacking.

8 Oct 2026

Spatial Single-Cell Transcriptomics Maps Cellular Niches in Fatal COVID-19 Lungs

Researchers at the University of Liège have used imaging-based spatial single-cell transcriptomics to map the cellular organization of lungs from people who died with severe COVID-19.

5 Oct 2026

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Antiretroviral drugs let people with HIV live full-length lives, but cognitive problems often persist. Some studies have found cognitive impairment in as many as half of people receiving antiretroviral therapy, although estimates vary and many cases do not interfere with daily activities.

24 Sep 2026

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous. Previously, the identity of these surviving cells was unclear.

11 Sep 2026

Newly Found Fibroblasts Help Lung Tumors Evade Immune System

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

28 Aug 2026

Mapping Diverse Brain Cell Populations Unlocks Deep Hidden Molecular Secrets

Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue.

22 Aug 2026

New Transcriptomic Framework Identifies Early Cell Damage Before Organ Failure

Researchers at the University of Cologne, University Hospital Cologne, and the Max Planck Institute for Metabolism Research have developed a method that, for the first time, enables damage to individual cells to be precisely quantified.

22 Aug 2026

Single-Cell Study Decodes Ancient Plant Partnership With Soil Fungi

Scientists at VIB and Ghent University have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi.

19 Aug 2026

High Resolution Imaging Exposes Root Causes of Chronic Heart Rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

13 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

New Research Reveals Cellular Switches Driving Physical Adaptation in Marine Species

In the animal kingdom, only those who adapt to their environment will survive. This adaptation comes in a wide range of forms, from invisible internal shifts in gene expression to dramatic anatomical changes, such as tadpoles growing legs and transitioning to life on land as frogs.

8 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Gut Microbiome Signatures Correlate With Clinical Efficacy in Immunotherapy Outcomes

Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.

9 Jul 2026