Transcriptomics News and Research

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spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

Plants Activate Immunity Instead of Growth During Drought Recovery

A plant's number one priority is to grow-a feat that demands sunlight, nutrients, and water. If just one of these three inputs is missing, like water in a drought, growth halts.

2 Sep 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

Exploring the Regulatory Potential of "Junk DNA"

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and a key factor in understanding complex diseases.

25 Aug 2025

Salk Researchers Create First Genetic Atlas to Span the Entire Arabidopsis Life Cycle

Nearly everything you know about plants was first discovered in a plant you've likely never heard of. Arabidopsis thaliana, also known as thale cress, is a small, flowering weed that has shaped much of plant biology as we know it.

20 Aug 2025

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

29 Jul 2025

New Computer Program Mimics Human and Animal Cell Behavior

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

New R Package Simplifies Interpretation of Gene Enrichment Results

Scientists at China Pharmaceutical University have launched GseaVis, a groundbreaking R package designed to transform how researchers visualize and interpret Gene Set Enrichment Analysis (GSEA) results in biomedical research.

21 Jul 2025

Researchers Combine AI and CRISPR to Rejuvenate Ovarian Function

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

21 Jul 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Integrating Imaging and Molecular Profiling to Transform Treatment of Intrahepatic Cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Unlocking Drug Discovery with SOAR's Innovative Resource

Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases.

13 Jun 2025

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

A new single-cell RNA analysis method, STAMP, significantly reduces costs and biases, allowing for comprehensive profiling of diverse cell populations.

13 Jun 2025

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

10 Jun 2025

Study Reveals How APOE Isoforms Impact Brain Microglia

A study reveals how APOE isoforms influence microglial activity in Alzheimer's, highlighting the need for targeted interventions based on genetic risk factors.

28 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Study Sheds Light on Development and Evolution of the Human Hypothalamus

The hypothalamus is a small but critical region at the base of the brain that controls the autonomic nervous system, regulates body temperature, signals hunger and thirst, exerts hormonal control over the pituitary gland, helps set circadian rhythms, influences sexual behavior and reproduction, and plays a role in instinctive behaviors like fear, aggression, and maternal bonding.

9 Apr 2025

Mapping Larger Tissue Sections Without Specialized Equipment

By creating comprehensive maps of the locations of gene expression in tissue, spatial transcriptomics technologies have made it possible to perform new types of biological assessments.

4 Apr 2025

AGD Initiative Drives Progress in Drug Discovery with Sequencing of 250,000 Whole Genomes

Nashville Biosciences LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, and global DNA sequencing giant Illumina Inc. today announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative.

22 Mar 2025

Spotiphy Revolutionizes Spatial Transcriptomics with AI for Single-Cell Resolution

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue.

14 Mar 2025

Transcriptomics News and Research

spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Plants Activate Immunity Instead of Growth During Drought Recovery

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

Exploring the Regulatory Potential of "Junk DNA"

Salk Researchers Create First Genetic Atlas to Span the Entire Arabidopsis Life Cycle

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

New Computer Program Mimics Human and Animal Cell Behavior

New R Package Simplifies Interpretation of Gene Enrichment Results

Researchers Combine AI and CRISPR to Rejuvenate Ovarian Function

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Integrating Imaging and Molecular Profiling to Transform Treatment of Intrahepatic Cholangiocarcinoma

Unlocking Drug Discovery with SOAR's Innovative Resource

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Study Reveals How APOE Isoforms Impact Brain Microglia

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Study Sheds Light on Development and Evolution of the Human Hypothalamus

Mapping Larger Tissue Sections Without Specialized Equipment

AGD Initiative Drives Progress in Drug Discovery with Sequencing of 250,000 Whole Genomes

Spotiphy Revolutionizes Spatial Transcriptomics with AI for Single-Cell Resolution

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