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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Transitioning Pancreatic Cells Retain Cancer Linked Epigenetic Marks

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

25 Apr 2025

New Genetic Insights From Long Read Sequencing in a Teen With Complex Psychiatric Conditions

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

12 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

Researchers Develop Cellulose-Based 3D Scaffolds That Mimic Natural Tissue Architecture

This research outlines a protocol for nano-fibrillated cellulose scaffolds, crucial for tissue engineering, emphasizing mechanical stability and cell viability.

9 Apr 2025

New Research Reveals Mitochondrial Guardians Linked to Parkinson’s and ALS

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

Digital Holographic Microscopy Reveals Microbial Biosignatures in Harsh Environments

New research from Portland State University focused on identifying signs of life - biosignatures - in extreme environments here on Earth.

7 Apr 2025

X and Y Chromosome Genes Compete for Sperm Success in Mice

In evolutionary terms, fitness is defined as an organism's ability to survive and reproduce its genes into the next generation.

7 Apr 2025

Scientists Discover Epigenetic Marks in Pancreatic Cancer Transition

7 Apr 2025

Novel Protein Analysis Technique Offers Fresh Insights into Immune System Disorders

A study conducted by researchers at Oregon Health & Science University has revealed a novel mechanism by which proteins can be modified within cells. This finding may have significant implications for the understanding of immune system functionality.

1 Apr 2025

Scientists Capture How Glutamate Opens Neuron Signaling Channels

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter.

29 Mar 2025

New AI Model Helps Predict Future Mutations in SARS-CoV-2 Spike Protein

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about its future evolution remain.

28 Mar 2025

Serendipitous Discovery Reveals How Whole-Genome Duplication Drives Evolution

Sometimes, the most significant scientific discoveries happen by accident. Scientists have long known that whole-genome duplication (WGD) - the process by which organisms copy all their genetic material - plays an important role in evolution.

27 Mar 2025

Zika and Dengue Virus Use Different Strategies to Infect Dendritic Cells

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

26 Mar 2025

How Drug-Resistant Bacteria Use Antimicrobial Tools to Outcompete Others

A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominate strain.

24 Mar 2025

Unveiling Bacterial Immune Mechanisms Against Temperate Phages

Like humans, bacteria can be attacked by viruses. In the case of bacteria, these viral attackers are referred to as bacteriophages, a term derived from the Greek word for bacteria-eaters, or simply “phages.”

24 Mar 2025

Study Reveals How Syngap1 Gene Affects Touch-Based Perception in Mice

You may scarcely notice it, but much of what you do every day requires your brain to engage in perceptual learning.

14 Mar 2025

Study Explores the Physiological Role of Nwd1 Gene in MASH Pathogenesis

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

12 Mar 2025

Machine Learning Addresses Ancestral Diversity in Disease Prediction

To ensure that medical genetic research better represents and benefits people from all backgrounds, researchers at the University of Florida are filling a crucial gap in the field.

11 Mar 2025

Low-Cost, Flexible Protein Detection Platform for Global Health

Chemical and biomolecular engineers at Georgia Tech have created a plug-and-play platform for the detection of disease protein biomarkers that is straightforward, adaptable, and user-friendly, eliminating the need for expensive laboratory equipment.

10 Mar 2025

Tumor Cell Adhesion Could Help Predict Breast Cancer Spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

6 Mar 2025