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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Explore the groundbreaking work of Mark Bear, a leading figure in neuroscience, as he shares insights on synaptic plasticity, learning, and the future of neurological research.

12 Jun 2024

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

11 Jun 2024

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

10 Jun 2024

Study Unveils Broader Immune Response in EBV-MS Connection

Epstein-Barr virus (EBV) may have a greater effect on the development of multiple sclerosis (MS) than previously believed due to a higher level of cross-reactivity, which occurs when the immune system binds to the incorrect target.

10 Jun 2024

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

A fertilized egg can develop into a baby through the amazing process of cell division, while a malignant cell can become a malignant tumor. Since there is so much on the line, nature maintains strict control over it through a mechanism known as the cell cycle that scientists once believed they thoroughly understood.

7 Jun 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

New mosTF Microscopy System Enhances Real-Time Brain Plasticity Research

The brain's ability to learn comes from "plasticity," in which neurons constantly edit and remodel the tiny connections called synapses that they make with other neurons to form circuits.

6 Jun 2024

Genetic Clues Unveil New Insights into Restless Leg Syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

6 Jun 2024

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

6 Jun 2024

Impact of Rare Disease Mutation Could Extend to More Prevalent Conditions

REX1 is a gene that is meant to direct the maintenance of the entire body’s DNA, but new research shows that when people are born with mutated TREX1, the DNA suffers catastrophic damage over time, resulting in a deadly rare disease known as retinal vasculopathy with cerebral leukoencephalopathy (RVCL).

5 Jun 2024

Graph Neural Networks: A Novel Approach to Deciphering Gene-Enhancer Interactions

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

Neurons in the Visual System of Flies Exhibit Surprisingly Heterogeneous Wiring

Analysis of the connectome of Drosophila melanogaster provides new insights into how its visual system is organized / Research contribution by the FlyWire Consortium

4 Jun 2024

Brain Organoids Emerge as Powerful Tool for Drug Discovery in Mitochondrial Disease

The use of brain organoids in screening for drugs against mitochondrial diseases, which have hitherto presented challenges in treatment.

4 Jun 2024

New Trojan Horse Virus Potentially Linked to Severe Toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

3 Jun 2024

Astrocyte Receptor Effects Differ Dramatically Between Sexes

Weill Cornell Medicine scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models.

31 May 2024

C. elegans Study Reveals Impact of Embryonal Amphetamine Exposure

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug.

31 May 2024

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel.

29 May 2024

Modifying Cellular Interactions Near Amyloid Plaques May Offer New Alzheimer's Treatments

Researchers at Mount Sinai’s Icahn School of Medicine have achieved a big breakthrough in Alzheimer’s disease research by discovering a new technique to potentially slow or even stop disease development.

28 May 2024

Spiking neuron bridges the gap between biological and artificial neurons

Engineers from the University of Liège have made significant advances in the design of artificial neural networks by developing a new form of spiking neuron. The Spiking Recurrent Cell (SRC) is a novel model that combines ease of implementation with the capacity to replicate the dynamics of biological neurons.

28 May 2024

Brain News and Research

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Study Unveils Broader Immune Response in EBV-MS Connection

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

Columbia Studies Uncover Misidentification of Gut Stem Cells

New mosTF Microscopy System Enhances Real-Time Brain Plasticity Research

Genetic Clues Unveil New Insights into Restless Leg Syndrome

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

Impact of Rare Disease Mutation Could Extend to More Prevalent Conditions

Graph Neural Networks: A Novel Approach to Deciphering Gene-Enhancer Interactions

Neurons in the Visual System of Flies Exhibit Surprisingly Heterogeneous Wiring

Brain Organoids Emerge as Powerful Tool for Drug Discovery in Mitochondrial Disease

New Trojan Horse Virus Potentially Linked to Severe Toxoplasmosis

Astrocyte Receptor Effects Differ Dramatically Between Sexes

C. elegans Study Reveals Impact of Embryonal Amphetamine Exposure

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

Modifying Cellular Interactions Near Amyloid Plaques May Offer New Alzheimer's Treatments

Spiking neuron bridges the gap between biological and artificial neurons

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

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