Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

New Study Reveals Varied CAR T-Cell Therapy Benefits in Large B-Cell Lymphoma

New Study Reveals Varied CAR T-Cell Therapy Benefits in Large B-Cell Lymphoma

A study identifies three patient subgroups in large B-cell lymphoma, revealing distinct responses to CD19 CAR T cell therapy and enhancing precision medicine.

20 Jun 2025

Hundreds of Human Genes Found to Act Like On Off Switches

Hundreds of Human Genes Found to Act Like On Off Switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

19 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.

18 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Researchers Develop Promising Vaccine for Vaginal Yeast Infections

Researchers Develop Promising Vaccine for Vaginal Yeast Infections

The UGA vaccine offers a potential breakthrough in combating vaginal yeast infections, aiming to reduce reliance on antifungal drugs amid growing resistance.

18 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Targeting iRhom2 to Control ADAM17-Related Diseases

Targeting iRhom2 to Control ADAM17-Related Diseases

The atomic structures of ADAM17 and iRhom2, revealed by UC researchers, offer new avenues for developing precise treatments for chronic inflammatory conditions.

16 Jun 2025

Study Shows Fibronectin Tension Loss Correlates With Breast Cancer Progression

Study Shows Fibronectin Tension Loss Correlates With Breast Cancer Progression

Fibronectin fibers lose tension in invasive breast cancer, unlike in healthy or DCIS tissues, suggesting a mechanical marker for tumor progression.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

Unlocking Drug Discovery with SOAR's Innovative Resource

Unlocking Drug Discovery with SOAR's Innovative Resource

Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases.

13 Jun 2025

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

A new single-cell RNA analysis method, STAMP, significantly reduces costs and biases, allowing for comprehensive profiling of diverse cell populations.

13 Jun 2025

Semaphorin 3E Emerges as a Key Factor in Female Reproduction

Semaphorin 3E Emerges as a Key Factor in Female Reproduction

The discovery of the Sema3E pathway in ovulation by Cornell researchers could enhance understanding of infertility and improve reproductive health strategies.

13 Jun 2025

Bats Hold Clues to Natural Cancer Resistance

Bats Hold Clues to Natural Cancer Resistance

A study to look at why long-lived bats do not get cancer has broken new ground about the biological defenses that resist the disease.

11 Jun 2025

Y Chromosome Loss Weakens Cancer Immunity

Y Chromosome Loss Weakens Cancer Immunity

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

9 Jun 2025

IL-12 Adjuvant Shows Promise in Boosting T-Cell Immunity

IL-12 Adjuvant Shows Promise in Boosting T-Cell Immunity

Scientists are always searching for new weapons to add to their arsenal in the pursuit of creating vaccinations that would better support the body’s immune system in fending off disease.

9 Jun 2025

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

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