Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

AI Research Gives Unprecedented Insight Into Heart Genetics and Structure

A ground-breaking research study has used AI to understand the genetic underpinning of the heart’s left ventricle, using three-dimensional images of the organ.

12 Mar 2024

Tandem Repeat Expansions Linked to Cardiomyopathy Risk, Reveals Study

In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital for Sick Children (SickKids) have laid the groundwork for early detection of and future precision therapies for cardiomyopathy.

28 Feb 2024

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

31 Jan 2024

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Our genetic code includes over 15,000 specific sections that can be made into molecules called lincRNAs.

27 Apr 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

New insights into the underlying mechanism that causes arrhythmogenic cardiomyopathy

Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).

3 Mar 2023

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Monogenic cardiovascular disease is a genetic disease in which cardiovascular damage is the only or main phenotype. The total current number of patients worldwide exceeds 10 million.

9 Feb 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Cell-derived therapy may help treat ventricular arrhythmia

Vesicles secreted from human heart cells may repair damaged tissue and prevent lethal heart rhythm disorders, according to a new study from investigators in the Smidt Heart Institute at Cedars-Sinai.

13 Apr 2022

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

A genome-wide association study has identified several common genetic loci (genetic locations) associated with dilated cardiomyopathy in U.S. veterans of European and African ancestry, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

9 Nov 2021

Cardiomyopathy News and Research

AI Research Gives Unprecedented Insight Into Heart Genetics and Structure

Tandem Repeat Expansions Linked to Cardiomyopathy Risk, Reveals Study

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

New insights into the underlying mechanism that causes arrhythmogenic cardiomyopathy

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

Cell-derived therapy may help treat ventricular arrhythmia

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

Study analyzes the role of heart cell protein as a potential therapeutic for heart failure

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Study offers renewed hope for children suffering from myofibrillar myopathies

Scientists identify heart cells responsible for repairing damaged heart after infarction

Study reveals molecular mechanism that regulates filament-like proteins in heart muscles

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