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Unveiling the Antimicrobial Potential of 28 Actinomycetes

Researchers from the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH's Department Bioresources for Bioeconomy and Health Research, under the direction of Dr. Imen Nouioui and Professor Dr. Yvonne Mast, have characterized 28 actinomycetes and examined their potential for biotechnology.

28 Nov 2024

Mitochondria Found to Play Key Role in Balancing Cell Death and Inflammatory Response

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria.

27 Nov 2024

Study Reveals Molecular Mechanism Behind Neural Fate Commitment

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development -; which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

Breakthrough in Understanding DNA Gyrase Paves Way for New Antibiotics

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target.

27 Nov 2024

New Tool to Unravel the Secrets of Malaria Parasite Adhesion

To better understand the highly varied characteristics that enable malaria parasites to adhere to red blood cells and elude the immune system, researchers have developed a new tool.

27 Nov 2024

Unveiling the Epigenetic Landscape of Blood Cancers

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes.

27 Nov 2024

Single-Cell Analysis Sheds Light on Leukemia Cell Heterogeneity

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

26 Nov 2024

Cyanobacteria Harness Pulse Amplitude Modulation to Control Biological Functions

Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission.

26 Nov 2024

Redefining plant monitoring with innovative tactile sensor technology

In a recent article, researchers present an iontronic tactile sensory system combined with machine learning, enabling accurate classification of plant species and growth stages for precision agriculture.

26 Nov 2024

New Role for the Golgi Apparatus in Cancer Immunotherapy

The Golgi apparatus modifies, sorts, and packages proteins to be sent to their final destinations, whether that is within or outside of the cell.

25 Nov 2024

Novel Approach to Lipid Nanoparticle Engineering

To enhance mRNA distribution, Penn engineers have created an ideal “recipe” for ionizable lipids, which are essential components of lipid nanoparticles (LNPs), the molecules that underlie the COVID-19 vaccines and other cutting-edge treatments.

25 Nov 2024

Cell Shape and Surface Stiffness Drive Distinct Migratory Behaviors in Ovarian Cancer Cells

The spread of tumor from the primary cancer site to distant organs, called metastasis, has puzzled scientists for many years – they are only now beginning to pinpoint triggers and mechanisms that drive this process.

25 Nov 2024

Self-Eliminating e-Drive System Reverses Insecticide Resistance in Fruit Flies

Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective.

25 Nov 2024

Unveiling the Hidden Potential of SnoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

25 Nov 2024

Jackson ImmunoResearch Expands Product Line with Anti-GFP Antibodies

Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists seeking to harness the utility of the GFP (green fluorescent protein) tag.

25 Nov 2024

Unmasking the Molecular Mechanisms of Melanoma

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

24 Nov 2024

Hormonal Control of Caste Determination in Ants

Most ants have two morphologically differentiated adult castes - queens and workers - each irreversibly specialized for either reproduction or nonreproductive altruism such as foraging, defense and care of maternal brood. Adult gynes (virgin queens) normally have higher body mass, wings and frontal eyes, as well as enlarged ovaries and a sperm storage organ.

24 Nov 2024

Rutgers Researchers Uncover How Brain Cells Form Functional Networks

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

23 Nov 2024

Human Cell Atlas Consortium Makes Major Progress in Understanding the Human Body

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication today (20 November) of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

22 Nov 2024

Mapping of Mouse Intestine Sheds Light on Immune Control and Adaptability

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease.

22 Nov 2024