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Chromosome Abnormalities Found in Healthy Women’s Breast Cells

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

22 Nov 2024

Researchers Map DNA Repair Protein Activity in Human Cells

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells.

22 Nov 2024

Versatile Molecule with a New Role in Genome Maintenance

A multi-institutional team of researchers from the Georgia Institute of Technology has uncovered a hitherto unidentified function for RNA.

22 Nov 2024

Immunotherapy Advances: CAR T Cells Targeting GD2 Offer Hope for Glioma Patients

Findings suggest GD2-specific CAR T-cell therapy is a viable option for H3K27M-mutant gliomas, with significant tumor shrinkage and clinical benefits observed.

22 Nov 2024

Ancient DNA Unlocks Secrets of European Genetic Adaptation

Leveraging a unique statistical analysis and applying it to ancient DNA extracted from human skeletal remains, a team of researchers from The University of Texas at Austin and the University of California, Los Angeles has revealed new insights into how ancient Europeans adapted to their environments over 7,000 years of European history.

21 Nov 2024

Molecule Found to Aid Intestinal Healing and Prevent Tumor Growth in Colorectal Cancer

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer.

21 Nov 2024

Novel Cellular Atlas of the Human Gastrointestinal Tract

Spatial and single-cell data from 1.6 million cells have been combined to produce the most complete cell map of the human stomach to date.

21 Nov 2024

Cancer-Causing Mutations Found in Healthy Breast Tissue

Williams, M. J., et al. (2024) Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations. Nature Genetics. doi.org/10.1038/s41588-024-01988-0.

21 Nov 2024

Novel Mechanism Revealed for Zygotic Genome Activation in Drosophila

Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA).

20 Nov 2024

Study Reveals Mystery Behind Extra Genes in Coronaviruses

Viruses are lean, mean, infection machines. Their genomes are tiny, usually limited to a handful of absolutely essential genes, and they shed extra genomic deadweight extremely fast.

20 Nov 2024

Scientists Use Cell Density to Control Tissue Formation

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs.

20 Nov 2024

Understanding Marine Worms’ Unique Ability to Regenerate Lost Body Parts

Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood.

19 Nov 2024

Study Reveals Key Role of Interleukin-38 in Skin Renewal

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating inflammatory responses, could be a game changer.

19 Nov 2024

Novel Mechanism of Photoprotection in Marine Microalgae

A nice item in excess is not good at all. Living things prefer sunlight in fact, they require it to survive but they tend to shun excessively strong light. Humans take naps, animals seek refuge, and even plants have defenses against too much light.

19 Nov 2024

New Imaging Technique Reveals Microbial Interactions

Numerous species of oral bacteria have been identified by scientists, but there are still many unanswered questions about how they interact.

19 Nov 2024

Hepatitis E Virus Impairs Neuronal Cells, Reducing Neurite Length

For the first time, scientists can examine the effects of hepatitis E viruses on nerve cells using a novel cell model.

19 Nov 2024

Study Reveals Key Role of Viscoelasticity in Cellular Response to Mechanical Signals

A study by CNIC, published in Science Advances, offers a new approach to understanding how cells respond to mechanical signals from their environment, redefining the comprehension of the relationship between cells and their physical surroundings.

18 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

Unveiling the Mechanisms of Phenotypic Heterogeneity in M. tuberculosis

The only single-celled organism ever found to sustain a steady growth rate throughout its life cycle is the rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again named the leading infectious disease killer worldwide.

18 Nov 2024

London Ranked Top City in Europe for Life Sciences

A newly released report has named London the #1 city in Europe and #3 globally for life sciences, behind Boston and New York, and ahead of Amsterdam, Munich, Paris, San Francisco, and Singapore.

18 Nov 2024