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New Guidelines Address Ethical Concerns of Stem Cell Embryo Research in the UK

The UK’s first guidelines for research with stem cell-grown embryo models state that all studies involving these models should be overseen by a dedicated committee.

8 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024

Selfish No More: Genetic Elements Give Phages a Competitive Edge

Curious bits of DNA tucked inside genomes across all kingdoms of life historically have been disregarded since they don't seem to have a role to play in the competition for survival.

7 Jul 2024

New Genetic Circuit Forces Cancer Cells to Self-Destruct

Treating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians never know when, where and what resistance might emerge, leaving them one step behind.

5 Jul 2024

Bowel Cancer Cells Use Genetic On-Off Switch' to Evade the Immune System

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical Center Utrecht.

4 Jul 2024

UCL Study Uncovers Astrocytes' Role in Brain Energy Boosting Mechanism

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

4 Jul 2024

Understanding How Motorized Processes Shape Chromosome Structures and Influence Cellular Functions

Researchers at Rice University are making strides in understanding how chromosome structures change throughout the cell's life cycle.

4 Jul 2024

Innovative Approach to Protein Synthesis Funded by $2 Million Grant

The National Institutes of Health's Maximizing Investigators' Research Award (MIRA) program for established investigators has awarded Rice University chemist Han Xiao with nearly $2 million.

4 Jul 2024

Metabolic Priming of CAR T Cells for Treatment of Solid Tumors

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.

3 Jul 2024

TRPC5 Gene Alterations: A Key Player in Obesity and Postpartum Depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

3 Jul 2024

Small Molecules Offer Precise Control Over Splicing in Gene Expression

The correct functioning of cells relies heavily on the ability to finely control gene expression, a complex process by which the information contained in DNA is copied into RNA to eventually give rise to all the proteins and most of the regulatory molecules in the cell.

3 Jul 2024

AI Uncovers Cancer Drivers in Non-Coding DNA

Researchers at the Garvan Institute have discovered putative drivers of cancer concealed in so-called "junk" DNA regions, creating opportunities for novel approaches to diagnosis and treatment using artificial intelligence.

3 Jul 2024

Are Advances in AI Technology Transforming Immunohistochemistry Analysis in Pathology?

The platforms and AI-based programs that are being used to analyze immunohistochemical markers and interpret the results.

3 Jul 2024

Study Reveals Epigenetic Changes in Sperm from Non-Genetic Infertility Causes

How non-genetic factors can induce epigenetic modifications to the sperm and cause male infertility.

3 Jul 2024

Common Fat Cells Converted to Calorie-Burning Beige Fat in Mice

According to recent research from UC San Francisco, it is now possible to convert common white fat cells, which store calories, into beige fat cells, which burn calories to regulate body temperature.

2 Jul 2024

Enzymatic Breakdown of Bacterial Cell Wall Facilitates Antibiotic Resistance Gene Transfer

A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads.

2 Jul 2024

Targeting Pseudomonas aeruginosa Cell Wall Stress for Biofilm Control

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics.

2 Jul 2024

Unexpectedly Large Genomes Found in Mycena Mushroom Species

A study of multiple Mycena mushroom species reported in the journal Cell Genomics has found that they have unexpectedly large genomes.

1 Jul 2024

New Research Aims to Improve CAR-T Cell Therapy Effectiveness

CARISMa scientists at Goethe University Frankfurt introduced innovative CAR therapy that recognizes and specifically kills tumor cells. This cancer therapy is the focus of new federally funded LOEWE research.

1 Jul 2024

Mice Studies Shed Light on Serotonin and Memory

Memory regulation in humans and animal models is regulated by the serotonin 2C receptor in the brain, according to research from Baylor College of Medicine, the University of Cambridge in the United Kingdom, and affiliated institutions.

1 Jul 2024