Clinical Trial News and Research

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In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020

New gene test predicts risk of drug-induced liver injury

Researchers who were exploring ways to establish the feasibility of batches of small liver organoids have now identified a new testing approach.

9 Sep 2020

Mice study shows naturally-occurring metabolite improves longevity

According to results from a study, middle-aged mice had a better “old age” when the naturally-occurring metabolite, called AKG, was added to their food.

2 Sep 2020

New COVID-19 mouse model helps advance vaccine development

A new COVID-19 mouse model developed at the University of North Carolina at Chapel Hill captures many of the features of human disease and has helped advance a COVID-19 vaccine candidate to clinical trial.

28 Aug 2020

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

A new study by researchers at MassBiologics of UMass Medical School published in Nature Communications suggests that COVID specific IgA monoclonal antibodies may provide effective immunity in the respiratory system against the novel coronavirus - a potentially critical feature of an effective vaccine.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Gene targeting could lead to better treatment of glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

19 Aug 2020

New tumor gene test could help predict survival of women with ovarian cancer

A global team of medical researchers led by UNSW have developed a test that could help to predict survival for women diagnosed with ovarian cancer, and pave the way towards personalised treatment.

From The University of New South Wales (UNSW) 19 Aug 2020

Aspirin may increase risk of disease progression in older adults with advanced cancer

Results from a recent clinical trial indicate that for older adults with advanced cancer, initiating aspirin may increase their risk of disease progression and early death.

11 Aug 2020

West Virginia University performs revolutionary Alzheimer's treatment

A hospital nurse for 33 years, Nanette Miller would call her husband Frank at the end of each shift to let him know she was coming home.

10 Aug 2020

Researchers are developing therapeutic treatments for acute stroke

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

10 Aug 2020

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

AZoLifeSciences speaks to Dr. James Whittle and Professor Geoff Lindeman about their research in enhancing breast cancer therapy through killing sleeper cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 6 Aug 2020

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas.

5 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

3 Aug 2020

Rapid drug development yields potential treatment for yellow fever

Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths.

From Massachusetts Institute of Technology (MIT) 30 Jul 2020

Clinical Trial News and Research

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

New gene test predicts risk of drug-induced liver injury

Mice study shows naturally-occurring metabolite improves longevity

New COVID-19 mouse model helps advance vaccine development

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

Researchers add a component to make cancer vaccine more effective

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Gene targeting could lead to better treatment of glioblastoma tumors

New tumor gene test could help predict survival of women with ovarian cancer

Aspirin may increase risk of disease progression in older adults with advanced cancer

West Virginia University performs revolutionary Alzheimer's treatment

Researchers are developing therapeutic treatments for acute stroke

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

New study may offer a novel, potential target for treating breast cancer

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Old part of immune system may influence severity of COVID-19

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Rapid drug development yields potential treatment for yellow fever

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