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Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

AZoLifeSciences speaks to Dr. James Whittle and Professor Geoff Lindeman about their research in enhancing breast cancer therapy through killing sleeper cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 6 Aug 2020

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas.

5 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

3 Aug 2020

Rapid drug development yields potential treatment for yellow fever

Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths.

From Massachusetts Institute of Technology (MIT) 30 Jul 2020

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

A treatment for multiple myeloma that harnesses the body's cancer-fighting T cells was safe in humans and showed preliminary signs of effectiveness, according to a clinical trial involving 23 patients with relapsed or treatment-resistant disease.

30 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Clinical Trial News and Research

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

New study may offer a novel, potential target for treating breast cancer

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Old part of immune system may influence severity of COVID-19

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Rapid drug development yields potential treatment for yellow fever

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

New approach is more effective in treating certain blood cancers

Fusion protein found to effective at treating pulmonary arterial hypertension

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Scientists gain insights into how parasitic bacterium gives rise to lesions

New, promising CAR T cell therapy results in exceptional patient recovery

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

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