Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Research analyzes horizontal gene transfer between viruses and eukaryotes

The level at which viruses can pick up genes from their hosts to hone their infection process is illustrated by the first analysis of viral horizontal gene transfer.

7 Jan 2022

PhoreMost and POLARISqb announce a multi-target collaboration to investigate next-generation cancer therapies

PhoreMost Limited and Polaris Quantum Biotech (POLARISqb) today announced a collaboration to study oncology targets currently considered undruggable.

From PhoreMost 6 Jan 2022

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

A new technique takes bioprinting -; in which an ink of cells is printed, layer by layer, to form a structure -; to a whole new, and icy level. Investigators from the Zhang lab at Brigham and Women's Hospital have developed a technology that they term "cryobioprinting," a method that uses a bioink embedded with cells to print frozen, complex structures that can be easily stored for later use.

31 Dec 2021

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

New computational method could help quickly screen billions of drug compounds

Receptors are docking stations found on the surface of cells. Compounds such as caffeinE, dopamine, THC, and LSD, all bind to these receptors.

17 Dec 2021

Developing Sperm Cells from Primate Stem Cells

We speak to Professor Charles Easley about his latest research into male infertility, and how sperm cells could be potentially developed from primate stem cells.

From University of Georgia 15 Dec 2021

Study finding helps better comprehend necroptosis for treating diseases

A group of scientists from WEHI, for the first time, visualized a human cell death complex associated with autoimmune and inflammatory conditions.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 14 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

Study uncovers an immune evasion mechanism of SARS-CoV-2

Scientists discovered that SARS-CoV-2 can knock out a significant molecular pathway associated with an immune complex named MHC class I.

8 Dec 2021

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Metrion today announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability.

From Metrion Biosciences Limited 7 Dec 2021

Custom Biofluid & Tissue Procurement Service

Global provider of human and animal biospecimens - AMSBIO offers a custom procurement service enabling researchers to source specific biofluid and tissue samples which are not already available in their extensive biorepository.

From AMS Biotechnology 1 Dec 2021

Study finds a more sustainable way to develop pharmaceuticals

University of Bath’s chemistry researchers recently devised a novel process utilizing blue light to develop pharmaceuticals in sustainable means.

From University of Bath 19 Nov 2021

bit.bio appoints Kathryn Corzo as Chief Operating Officer

Cell coding company bit.bio today announces the key appointment of Kathryn Corzo as Chief Operating Officer. She started in the role on 1 November 2021.

From bit.bio 19 Nov 2021

Biognosys Launches Next-Generation Blood Biomarker Discovery Solution

Biognosys today announces the launch of its next-generation blood biomarker discovery solution, which will be offered as a contract research service.

From Biognosys 10 Nov 2021

CN Bio and iiCON announce COVID-19 research collaboration

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools.

From CN Bio Innovations Limited 9 Nov 2021