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AI Predicts Multiple Protein Shapes, Boosting Drug Development

By understanding protein dynamics and functions, a group of academics at Brown University have devised a method for quickly predicting various protein configurations using machine learning.

28 Mar 2024

To Bolster Global Efforts in Combating Antibiotic-Resistant Bacteria KFSH&RC Scientists Discover New Bacteria Species: Riyadhensis

In a ground-breaking development, scientists at King Faisal Specialist Hospital and Research Centre (KFSH&RC) have identified a new species of bacteria, referred to as "Stenotrophomonas Riyadhensis" through the application of whole-genome sequencing (WGS) technology.

27 Mar 2024

The Influence of sRNA on Gut Pathogen Drug Susceptibility

A significant breakthrough in understanding how gut bacteria adapt to their environment.

26 Mar 2024

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

25 Mar 2024

Multi-Tailed Strucrure Expands the Horizons of mRNA Therapeutics

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

25 Mar 2024

Latest CRISPR-Cas Gene Editing Can Eliminate All Traces of HIV Virus From Infected Cells

New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands shows how the latest CRISPR-Cas gene editing technology can be used to eliminate all traces of the HIV virus from infected cells in the laboratory, raising hopes of a cure.

20 Mar 2024

Drug Candidates Show Promise to Reverse HIV's Ability to Escape Immune System Detection

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

20 Mar 2024

Novel Imaging Technique Unveils Structural Details of Drug-Resistant Cancer Protein

Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.

20 Mar 2024

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

Transcriptome Profiling Reveals Age-Associated Changes in the Human Brain

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

18 Mar 2024

Scientists Design Proteins to Reach Hidden Cellular Targets

Drug developers have long faced challenges in reaching targets embedded within the cell membrane because of the membrane's complex biochemical properties. Chemists at Scripps Research have now shown that novel, specially made proteins are capable of effectively reaching these “intramembrane” targets.

14 Mar 2024

Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 4, entitled, "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C."

14 Mar 2024

Investigating the Antibacterial Effects of T1-Spanin on Antibiotic-Resistant Bacteria

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13 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

A group of researchers in Newcastle has been investigating the part that vitamin A plays in the pathogenesis of psychiatric disorders.

12 Mar 2024

Multiresolution DNA Simulation in Viral Genome Packaging

Researchers at the University of Illinois Urbana-Champaign stated in the journal Nature that a computational model of the more than 26 million atoms in a DNA-packed viral capsid broadens the knowledge of virus structure and DNA dynamics, discoveries that potentially open up new research directions and therapeutic targets.

7 Mar 2024

Transition to Laser-Based 3D Bioprinting: Stride Towards Addressing Organ Shortage

Recent advancements in laser technology are leading to groundbreaking developments in the medical field, from improved treatment of cardiovascular diseases to higher-precision manufacturing of medical devices.

7 Mar 2024

The Impact of Catalysis for Site-Specific Protein Modification

As they recently reported in the journal Nature Chemistry, Boston College researchers have developed a new tool that can be used to develop novel biotherapeutics and protein-based research tools: the ability to precisely modify proteins using a mild charge of electricity.

6 Mar 2024

CSHL Researchers Unravel Why Some Splicing-Based Drugs Tend to Work Better Than Others

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing.

6 Mar 2024

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

5 Mar 2024

Drugs News and Research

AI Predicts Multiple Protein Shapes, Boosting Drug Development

To Bolster Global Efforts in Combating Antibiotic-Resistant Bacteria KFSH&RC Scientists Discover New Bacteria Species: Riyadhensis

The Influence of sRNA on Gut Pathogen Drug Susceptibility

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Multi-Tailed Strucrure Expands the Horizons of mRNA Therapeutics

Latest CRISPR-Cas Gene Editing Can Eliminate All Traces of HIV Virus From Infected Cells

Drug Candidates Show Promise to Reverse HIV's Ability to Escape Immune System Detection

Novel Imaging Technique Unveils Structural Details of Drug-Resistant Cancer Protein

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Transcriptome Profiling Reveals Age-Associated Changes in the Human Brain

Scientists Design Proteins to Reach Hidden Cellular Targets

Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

Investigating the Antibacterial Effects of T1-Spanin on Antibiotic-Resistant Bacteria

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

Multiresolution DNA Simulation in Viral Genome Packaging

Transition to Laser-Based 3D Bioprinting: Stride Towards Addressing Organ Shortage

The Impact of Catalysis for Site-Specific Protein Modification

CSHL Researchers Unravel Why Some Splicing-Based Drugs Tend to Work Better Than Others

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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