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Maize Genotypes Shape Root Microbiome in Response to Environmental Stress

In order for plants to grow, they absorb water and nutrients through their roots. In doing so, they rely on tiny helpers: bacteria and fungi in particular are found in a thin layer around the roots.

22 Mar 2024

New Approach to Constructing Human Artificial Chromosomes Avoids Unintended Multimerization

Constructing human artificial chromosomes (HACs) in budding yeast overcomes the long-standing problem of uncontrolled multimerization – the rampant joining of similar molecules – and results in HACs that are large, stable, and structurally well-defined, researchers report.

22 Mar 2024

Non-Immune Cells Form Memory, Boosts Inflammatory Response

An essential component of adaptive immunity is immunological memory, which is the capacity to react to a foreign material or antigen more quickly and intensely when exposed again.

21 Mar 2024

Decoding the Dynamics of Multiple Sclerosis Lesions

Scientists in Sweden were able to uncover the molecular mechanisms behind the development of lesions in multiple sclerosis by employing sophisticated techniques. The latest findings are detailed in the journal Cell by a team of researchers from Karolinska Institutet and Stockholm University.

21 Mar 2024

AI Tool Discovers Hidden Diversity in Major Crops

Researchers have created a new computational tool that quickly and effectively exposes genetic variety inside DNA databases of different plant species, which is a significant advancement for agricultural science.

21 Mar 2024

Whole Genome Sequencing Reveals Genetic Influences on Alzheimer's Disease Risk

Identifying genetic variants and the role they play in predisposing people to Alzheimer's disease can help researchers better understand how to treat the neurodegenerative condition for which there is currently no cure.

21 Mar 2024

Researchers Identify RNA-Regulator Brat as Key Player in Restraining Tissue Regeneration

Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail.

20 Mar 2024

Latest CRISPR-Cas Gene Editing Can Eliminate All Traces of HIV Virus From Infected Cells

New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands shows how the latest CRISPR-Cas gene editing technology can be used to eliminate all traces of the HIV virus from infected cells in the laboratory, raising hopes of a cure.

20 Mar 2024

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

Using Genomic Methods to Track Pesticide Resistance

Pesticides are used by farmers to manage agricultural pests. However, pesticide-resistant insects frequently become immune to their toxins.

19 Mar 2024

Soil Bacteria Gene Discovery Offers Hope for Bioremediation Efforts

Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found.

19 Mar 2024

Students Work with Experts to Create a High-Quality Pear Genome Assembly

Pears are big business in the Pacific Northwest US. But did you know that traditional pear breeding has remained largely unchanged for centuries?

18 Mar 2024

SIRPβ1 Gene Mutation Alters Alzheimer's Disease Progression

The scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of research and brings together 100 multidisciplinary specialists, identifying a mutation that alters Alzheimer's disease progression.

18 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

Transcriptome Profiling Reveals Age-Associated Changes in the Human Brain

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

18 Mar 2024

How Does the Egg Coat Prevent Multiple Fertilization

The surrounding egg coat tightens once a sperm fertilizes an egg, mechanically blocking further sperm from entering and causing the embryo to die.

15 Mar 2024

Study Deciphers Mechanism That Helps Viruses Choose to Turn Nasty or Stay Friendly

Researchers from the Shmunis School of Biomedicine and Cancer Research at Tel Aviv University have deciphered a novel complex decision-making process that helps viruses choose to turn nasty or stay friendly to their bacterial host.

14 Mar 2024

Machine Learning Reveals Cancer-Causing DNA Repeats

It has been difficult to identify and characterize repeats of DNA sequences, also known as “junk DNA” or “dark matter,” that are found in chromosomes and may be involved in cancer or other diseases.

14 Mar 2024

Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 4, entitled, "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C."

14 Mar 2024

Researchers Unveil Simple Trick to Improve Accuracy Of Plant Genetics Research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables – such as temperature – affect gene activity in plants.

14 Mar 2024