Glycolysis is a series of reactions that helpextract energy from glucose. This is an ancient pathway of metabolism that is present in the majority of living organisms today. It is the foundation of both aerobic and anaerobic cellular respiration. It takes place in the cytosol of a cell and is the foundation of both aerobic and anaerobic cellular respiration.
Researchers have used bacteria to create sophisticated synthetic cells that imitate the activity of genuine cells.
The energy centers of cells and mitochondria have their own genetic material and RNA molecules.
A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.
A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.
Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.
Scientists from the Karolinska Institutet discovered certain metabolic mechanisms that SARS-CoV-2 employs to attack lung tissue.
Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.
Natural killer (NK) cells, while having a name straight out of a Tarantino film, are allies of humans when it comes to combating cancer and infections.
A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.
Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.
Scientists from The University of Texas MD Anderson Cancer Center have identified a protein known as NF-kappa B-inducing kinase (NIK).
A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.
Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.
While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.
A team of researchers have discovered a mechanism that prevents hair loss: hair follicle stem cells.
New research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by the overactivation of fructose made in the brain.
Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose at a much higher rate than normal cells.
When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.
New breakthrough in breast cancer could enable the development of better approaches to prevent the spread of cancer cells to other organs in the body, thereby effectively bringing down mortality in patients suffering from breast cancer.