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New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Natural killer cells target breast cancer using the body’s immune system

In a recent study, researchers investigated how natural killer cells target breast cancer using the body's own immune system.

18 Jun 2021

POSTECH researchers bioengineer a novel drug-delivering adhesive patch platform

Blood vessels deliver nutrients and oxygen to each organ in our body. They are difficult to completely restore to their original conditions once damaged by myocardial infarction or severe ischemic diseases. This is because various angiogenic growth factors must be applied sequentially in order to restore the vascular structure.

13 Apr 2021

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

25 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

New type of stem cell with regenerative abilities could soon become a reality

A new type of stem cell - that is, a cell with regenerative abilities - could be closer on the horizon, a new study led by UNSW Sydney shows.

From The University of New South Wales (UNSW) 15 Jan 2021

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.

8 Jan 2021

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

29 Dec 2020

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab.

24 Dec 2020

Placental gene expression related to preeclampsia may be affected by vitamin D status

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

10 Nov 2020

Pancreatic cancer cells avert starvation by signaling to nerves, shows study

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.

3 Nov 2020

Novel machine learning algorithm helps identify binding sites in drug targets

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential drug targets, in proteins.

27 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

7 Oct 2020

Researchers identify key molecules that contribute to radioresistance in glioblastoma

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

1 Oct 2020

Honeybee venom rapidly destroys aggressive breast cancer cells

Using the venom from 312 honeybees and bumblebees in Perth Western Australia, Ireland and England, Dr Ciara Duffy from the Harry Perkins Institute of Medical Research and The University of Western Australia, tested the effect of the venom on the clinical subtypes of breast cancer, including triple-negative breast cancer, which has limited treatment options.

2 Sep 2020

Scientists document communication pathways in SARS-CoV-2 infected human cells

In the transmission of signals within the cell which, for example, stimulate cell growth or trigger metabolic processes, phosphate groups play an important biochemical role.

26 Aug 2020

Study reveals key biomolecule that can heal damaged heart tissues

When a person suffers a heart attack, parts of the heart can become stiff and scarred, leading to disability and possible progression toward heart failure.