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Fasting-mimicking diet combined with hormone therapy has potential to treat breast cancer

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

22 Jul 2020

Novel nano drug candidate kills triple negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

21 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020

A new approach to combat drug resistance in aggressive age-related macular degeneration

An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly.

17 Jul 2020

Study identifies brain cells that control sugar intake and cravings

New research has identified the specific brain cells that control how much sugar you eat and how much you crave sweet tasting food.

13 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

Long-term culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

2 Jul 2020

Study identifies complex functional, physical interactions between p53 gene and the INSR pathway

Volume 11, Issue 25 of @Oncotarget reported that the present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells.

25 Jun 2020

New approach provides closer look at the development of multicellular organisms

Highly complex organisms can arise from a single cell, which is one of the true miracles of nature. Substances known as morphogens have an important role in this development, namely by signaling to cells where they should go and what they should do.

13 May 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

Experience Matters For Immune Cells

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer.

17 Apr 2020

Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

Scientists discover unexpected pathway by which brown fat can burn energy

When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy.

7 Apr 2020

Study sheds light on the mechanism of cell division

There is no clear consensus on when exactly cells decide to divide. For four decades, the answer provided in the textbook was that this decision takes place in the initial phase of the existence of a cell—that is, soon after a mother cell divides into daughter cells.

7 Apr 2020

Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020

IL-2's flexible structure helping the immune system

Scientists have known that interleukin-2 (IL-2), a signaling molecule, strongly influences the immune system. However, attempts to leverage its potential for therapeutic purposes have went futile due to serious side effects.

From University of California Santa Cruz 18 Mar 2020