Huntington's Disease News and Research

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Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations. A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision. As the disease progresses, concentration on intellectual tasks becomes increasingly difficult and the patient may have difficulty feeding himself or herself and swallowing. The rate of disease progression and the age of onset vary from person to person. A genetic test, coupled with a complete medical history and neurological and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. In 1 to 3 percent of individuals with HD, no family history of HD can be found.
Innovative gene therapy approach for regeneration of functional new neurons

Innovative gene therapy approach for regeneration of functional new neurons

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

Discovery Shows Promise For Treating Huntington's Disease

Discovery Shows Promise For Treating Huntington's Disease

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

New system of gene editing allows for targeted, super-fast DNA repair

New system of gene editing allows for targeted, super-fast DNA repair

Study uncovers two brain phenomena that may explain ketamine's side-effects

Study uncovers two brain phenomena that may explain ketamine's side-effects

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Study uncovers why developing nerve cells take a wrong turn

Study uncovers why developing nerve cells take a wrong turn

Study highlights crucial role of immune-system molecule in Huntington's disease

Study highlights crucial role of immune-system molecule in Huntington's disease