Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.
When two naturally occurring lipids are altered using a process called epoxidation, they are transformed into powerful agents that target numerous cannabinoid receptors in neurons, disrupting pathways that promote inflammation and pain.
Coral reefs are beautiful and diverse ecosystems that power the economies of many coastal communities. They're also facing threats that are driving their decline, including the planet's warming waters.
In science, sometimes a new perspective can turn our interpretation of the data upside-down, and necessitate a paradigm shift.
Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.
Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given rise to an entire field of study known as "chronobiology".
In this interview, AZoLifeSciences speaks to Dr. Noemi Procopio about her latest research which involved using bone proteomics to determine the length of time a corpse had been left underwater.
Cells, the basic unit of life, are surrounded by a limiting membrane called the plasma membrane. Inside cells, there are various membrane-bounded organelles, each of which has various and distinctive functions.
A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.
Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin.
A new computational mass spectrometry imaging method enables researchers to achieve high mass resolution and high spatial resolution for biological samples while providing data sets exponentially faster.
A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine--a nonprofit of 12,000 doctors--debunks the "blood type diet" by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control.
Expansion microscopy, abbreviated as ExM, allows scientists to image cells and their components with a spatial resolution down to 200 nm.
Thousands of years ago, people in South America began domesticating Solanum pimpinellifolium, a weedy plant with small, intensely flavored fruit. Over time, the plant evolved into S. Lycopersicum - the modern cultivated tomato.
If there is a positive aspect in cancer’s random biology, it is that the same characteristics that promote the growth of cancer cells usually present opportunities for destroying them.
University of Louisville researchers have found a less toxic way to deliver medicines by using the natural lipids in plants, particularly grapefruit and ginger.
Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.
There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.
New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.
Trial participants who received a multinutrient formulation over an extended period of time showed a significantly less rapid deterioration in cognitive performance than the patients in a control group, who received only a placebo.
Drs. Nobuo Noda (Director) and Kazuaki Matoba (Senior Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) between the two layers of the lipid bilayer and elucidated that the protein's activity brings about autophagosome membrane expansion.