Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.
Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.
The University of Konstanz’s Plant Physiology and Biochemistry research group has discovered previously unrecognized molecular mechanisms by which plants acclimatize to their environment—vital basic knowledge in times of climate change.
AZoLifeSciences sat down with Tom Kwoka, Senior Application Scientist - GC/MS at PerkinElmer, and Alex Maitain, GC/MS Cannabis Analysis at PerkinElmer, to discuss the benefits of analyzing residual solvents and terpenes from cannabis and hemp products by Headspace GC/MS analysis.
Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer.
The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.
Membrane proteins are vital therapeutic targets. They exist between the interior and exterior of human cells. Some of them, known as “transporters,” transport substances into and out of the cellular environment.
Chronic heart failure induces dysfunction in the cell’s powerhouses, which is caused in part by an excess of an essential intermediate compound in energy production. Compensating for this by supplementing the diet could be a potential technique for treating heart failure.
Most people do not realize that fatty acids can be found in a nutritious salad. Although fatty acids, lipids, and fats may seem unappealing, they are essential to human life and to the plants that are consumed.
Professor Stefan Mecking from the University of Konstanz’s Department of Chemistry and Doctoral Candidate Natalie Schunck have now discovered a means to significantly increase the efficiency of the process of upgrading sustainable raw materials.
University of Alberta’s study demonstrates the way cell membranes perform a much bigger role than that was understood in enabling spike proteins on viruses to affect cells.
According to a recent study, cancers can avoid both the immune system and cancer treatments that depend on it, including CAR T cells that have been genetically altered.
Scientists at the Universities of Bonn and Osnabrück have identified a protein that when defective in flies results in motor dysfunction.
Geckos are known for having sturdy feet that enable them to easily scale vertical surfaces. Millions of microscopic, hair-like structures on their toes provide them with this apparent superpower.
North Carolina State University researchers revealed that a crucial gene in maize called HPC1 modulates some chemical processes that contribute to flowering time.
The effects of global climate change already are resulting in the loss of sea ice, accelerated sea level rise, and longer and more intense heat waves, among other threats.
A recent genetic finding supports the theory that abnormal lipid (fat) transport pathways inside brain cells cause motor neuron degenerative disorders.
Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.
Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.
This scientific breakthrough, which was published in the science journal Theranostics, might pave the way for cancer patients to prevent developing metastases.
Bacteria, fungi, and yeast are very good at excreting useful substances such as weak acids. One way in which they do this is through passive diffusion of molecules across the cell membrane. At the same time, cells need to prevent leakage of numerous small molecules.