Liquid Chromatography News and Research

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Deep Proteomic Analysis Unveils Molecular Changes in Skeletal Muscle with Aging and Resistance Training

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Pure Capped mRNA Vaccine Opens the Door to More Effective Vaccines with Lower Chances of Inflammation

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

11 Oct 2023

Study: Swimming and Tubing Can Alter Stream Chemistry and Microbiology

With Labor Day approaching, many people are preparing to go tubing and swimming at local streams and rivers.

19 Sep 2023

Key Proteins in Human Breast Milk Crucial for Baby’s Healthy Gut

The abundance of two species of bacteria known to be good for human health and used as probiotics, Clostridium butyricum and Parabacteroides distasonis, has been linked to high concentrations of key proteins in human breast milk, particularly osteopontin and κ-casein.

13 Sep 2023

Newly Discovered Fungus Helps Destroy a Harmful Food Toxin

Patulin is a harmful mycotoxin produced by fungi typically found in damaged fruits, including apples, pears, and grapes.

1 Sep 2023

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

6 Jul 2023

New Way to Conduct Extensive Proteome Analysis of Urine

Urine is one of the alluring sources for early and sensitive biomarker discovery because it can accumulate and indicate changes in the human body while still being obtained non-invasively.

16 Jun 2023

Beef, pork, chicken, and other meats contain new antioxidants, analysis reveals

Imidazole dipeptides (IDPs), which are abundant in meat and fish, are substances produced in the bodies of various animals, including humans, and have been reported to be effective in relieving fatigue and preventing dementia.

17 Feb 2023

Novel analytical platform quantitatively characterizes mRNA vaccines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

14 Feb 2023

Robust new method accurately identifies eight antidepressants

In recent years, a mass spectrometry process that can detect the amounts of drugs in a biological sample, such as blood, has become a powerful diagnostic tool for helping medical professionals identify and monitor levels of therapeutic drugs in patients, which can cause unwanted or dangerous side effects.

14 Feb 2023

Learning about cellular proteins through “snapshots” of translation

Pep-tRNAs, nascent polypeptides inside the ribosome that are covalently connected to transfer RNA, are engaged in a variety of cell processes, including gene expression, according to advances in molecular biology.

1 Feb 2023

Drug discovery method facilitates promising treatment approaches for metabolic diseases

The body’s chemical processes known as “metabolism” produce the raw materials needed for development and general health.

17 Oct 2022

Researchers identify new set of protein biomarkers for cancer using breast milk

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

5 Apr 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

Biognosys Launches Next-Generation Blood Biomarker Discovery Solution

Biognosys today announces the launch of its next-generation blood biomarker discovery solution, which will be offered as a contract research service.

From Biognosys 10 Nov 2021

Researchers develop a new method for monitoring organic pollutants using plants

Researchers at Kobe University's Biosignal Research Center have successfully developed plants that can be used to detect organic pollutants, such as polychlorinated biphenyls and endocrine-disrupting chemicals, which contaminate soil and water.

9 Sep 2021

Researchers report several compounds responsible for coffee’s distinctive mouthfeel

Coffee drinkers intuitively recognize the pleasure of swallowing a smooth, rich brew versus a watery one. Aside from added cream or sugar, the coffee itself contributes to this sensation -; referred to as body or mouthfeel -; but the specific compounds are not well defined.

24 Aug 2021

Determining class A drug use from a single fingerprint

AZoLifeSciences speaks to Dr. Catia Costa about her latest research that showed how class A drug use can be determined from a single fingerprint.

From University of Surrey 29 Jun 2021

Using proteomics to determine how long a corpse has been underwater

In this interview, AZoLifeSciences speaks to Dr. Noemi Procopio about her latest research which involved using bone proteomics to determine the length of time a corpse had been left underwater.

From Northumbria University 11 Jan 2021