Lymph Nodes News and Research

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Researchers study how trypanosomes change the predatory bug’s intestinal microbiota

In Central and South America, predatory blood-sucking bugs transmit the causative agent of the widely prevalent Chagas disease.

22 Mar 2022

Researchers use cryo-EM to rapidly characterize antibodies at atomic level

Scripps Research scientists have found a mechanism that may be able to bypass one of the critical steps in current vaccine production.

24 Jan 2022

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures.

12 Jan 2022

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

Study helps identify how immune system cells identify and eradicate tumors

In the last 10 years, immunotherapy has been used to save the lives of several cancer patients with lung cancer.

13 Dec 2021

New nanoparticle adjuvant could lead to more powerful vaccines

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

6 Dec 2021

Study reveals what causes T cells to be non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

1 Nov 2021

Scientists reveal the importance of circadian rhythm on the immune system

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

19 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Clinical efficacy of CAR-T cells depends on chemical modifications, says study

One in five cancers affects lymph nodes and blood cells resulting in lymphomas and leukemias, respectively.

7 Oct 2021

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can also be synthesized by the body or artificially developed in laboratories.

From Tokyo University of Science 1 Oct 2021

Novel T cells reside in lymph nodes and offer protection against melanoma

Immunotherapy is an advancing field but there is limited knowledge on the immunity to metastatic tumors in locations like lymph nodes.

20 Sep 2021

Research identifies an unnoticed site for priming of CD8+ T cells—the spleen

CD8+ T cells, also called “killer” T cells, are the killers of the immune system. Upon being primed, they look for and kill cancerous cells or virus-infected cells.

14 Sep 2021

UAB researchers identify an unnoticed additional site for priming of "killer" T cells

CD8+ T cells -; known as "killer" T cells -; are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

13 Sep 2021

Stem-like T cells found in certain lymph nodes could be natural cancer fighters

Researchers performed a new study and demonstrated that stem-like T cells found in some lymph nodes could exhibit natural cancer-fighting properties.

7 Sep 2021

Study uncovers key factors immune cells need to survive in the battle against cancer

A study headed by scientists at Massachusetts General Hospital unravels certain crucial factors required for the survival of immune cells in the fight against cancer.

12 Aug 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

19 Jul 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Scientists successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020