Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Researchers uncover problems with the conventional method for growing organoids

Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years.

1 Oct 2020

Researchers uncover tissue reparative role for a rare immune cell in the gut

Scientists from King's College London have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if dysregulated.

9 Sep 2020

New gene test predicts risk of drug-induced liver injury

Researchers who were exploring ways to establish the feasibility of batches of small liver organoids have now identified a new testing approach.

9 Sep 2020

Newly developed transplantable human cells can help cure type 1 diabetes

Researchers have made a significant advancement in the quest for a safe, effective treatment for type 1 diabetes.

20 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

Study reveals key factor that influences malignant cells to develop into tumor

Researchers have unraveled a crucial factor that governs whether malignant cells will develop into a tumor. The study was recently published in the eLife journal.

22 Jul 2020

SOAT1 enzyme offers a promising therapeutic target for pancreatic cancer

Researchers from CSHL have discovered that the growth of pancreatic cancer cells can be stopped by disrupting the way cholesterol is stored by the cells.

8 Jul 2020

Organoids reveal inflammatory processes that play a role in infectious diseases

Research is employing mini-organs to model the digestive tract in the laboratory setting. These supposed organoids shed light on the inflammatory processes.

6 Jul 2020

Lab-grown 'mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

1 Jul 2020

Transcriptomic data can help track Neanderthal-derived RNA

Scientists are taking stem cell technology and using it to explore the developmental impacts of Neanderthal DNA.

19 Jun 2020

Cardiac organoids that closely mimic physiological conditions during a heart attack

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

12 Jun 2020

Lab-grown organoids can prevent hair loss

Researchers have created a new, hair-germinating piece of human skin in the laboratory that might prevent hair loss in the days to come.

4 Jun 2020

A remote optical stimulation for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

2 Jun 2020

Biosynthetic capacity allows cancer stem cells to contribute to tumor growth

Tumors are not a consistent cluster of cells. In fact, colon cancers carry differentiated-like cells, just like the functional cells of the intestinal wall and pluripotent cells—the supposed tumor stem cells.

13 May 2020

Breaking Down the DNA Behavior of Cancer Cells

Dr. Manel Esteller speaks to AZoLifeSciences about his ground-breaking cancer research in which he uncovered the behavior of DNA in 3D models.

From University of Barcelona 13 May 2020

New DNA study can revolutionize cancer treatment

In a new study, researchers have used 3D models to disintegrate the DNA behavior of tumor cells, paving the way for innovative treatment for the disease.

11 May 2020

Lipid metabolism enzyme regulates brain stem cell activity

Neural stem cells play a major role in the early development of the brain and they also continue to remain active throughout the lifetime.

11 May 2020

Researchers design novel cell culture model of human intestine to study COVID-19

Scientists have identified that the coronavirus SARS-CoV-2, known to cause COVID-19, infects intestinal cells and undergo proliferation there.

4 May 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020