The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.
Recent research from the School of Medicine has illuminated the development of the liver, lungs, and digestive system. This result may have significant ramifications for the comprehension of cancer.
For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.
A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.
As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.
Research studying the autoimmune response, in which the immune system kills the insulin-producing pancreatic islet beta cells, is a common topic of type 1 diabetes research.
A new study performed has offered better knowledge about how genetic factors tend to impact the immune response of the body in type 1 diabetes.
The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.
The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.
Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.
One out of every 500 to 1,000 boys is born with one or more extra X chromosomes, which can cause a variety of symptoms as the extra chromosomes to including infertility, larger breasts, osteoporosis, diabetes, cardiac problems, intellectual incapacity, and cancer.
Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.
A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.
New advancements in the transplantation of stem cell-derived insulin-producing beta cells to cure type 1 diabetes have created substantial curiosity.
Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.
Pancreatic cancer is a unique, elusive, and fatal malignancy, with only approximately a 10% five-year survival rate.
Geneticists have revealed why some people with obesity remain relatively healthy, whilst others suffer from life-changing ailments such as type 2 diabetes and heart disease.
Glial cells in the heart help regulate heart rate and rhythm, and drive its development in the embryo, according to a new study publishing November 18th in the open-access journal PLOS Biology by Nina Kikel-Coury, Cody Smith and colleagues at the University of Notre Dame.
A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.
When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.