The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.
The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.
The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.
Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.
One out of every 500 to 1,000 boys is born with one or more extra X chromosomes, which can cause a variety of symptoms as the extra chromosomes to including infertility, larger breasts, osteoporosis, diabetes, cardiac problems, intellectual incapacity, and cancer.
Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.
A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.
New advancements in the transplantation of stem cell-derived insulin-producing beta cells to cure type 1 diabetes have created substantial curiosity.
Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.
Pancreatic cancer is a unique, elusive, and fatal malignancy, with only approximately a 10% five-year survival rate.
Geneticists have revealed why some people with obesity remain relatively healthy, whilst others suffer from life-changing ailments such as type 2 diabetes and heart disease.
Glial cells in the heart help regulate heart rate and rhythm, and drive its development in the embryo, according to a new study publishing November 18th in the open-access journal PLOS Biology by Nina Kikel-Coury, Cody Smith and colleagues at the University of Notre Dame.
A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.
When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.
Scientists recently demonstrated a process by which specific cell types in human organs can be investigated with micrometer precision.
Most of the cells in our bodies – be they bone, muscle or pancreas cells – are locked into the right place with the help of tiny anchors (called 'focal adhesions').
MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells.
Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.
Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.
AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.
Researchers revealed a predicted causative role for certain cell types in type 1 diabetes by examining its genetic foundations.