Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scientists successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Tau protein in Alzheimer's disease looks different at every dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Interleukin 10 levels could warn about the progression of COVID-19

Immunology experts have collaborated to use their groundbreaking research techniques to put people’s response to COVID-19 disease under the microscope.

16 Nov 2020

Study confirms correlation between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

New approach can prevent toxicity linked to neurological gene therapy

Scientists have deigned a new method to inhibit a toxicity observed in the sensory neurons of DRG following gene therapy to treat neurological diseases.

12 Nov 2020

Researcher develops procedures for defining preclinical stages of Alzheimer's disease

Both of Andrew Kiselica's grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother's father become unable to walk or speak due to severe dementia.

12 Nov 2020

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

No-tillage system helps maintain soil health and prevent erosion

Organic field crop farmers in the Northeast and Upper Midwest are facing an increasing number of challenges related to more extreme weather events and pest and disease outbreaks.

9 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Pancreatic cancer cells avert starvation by signaling to nerves, shows study

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.

3 Nov 2020

Study probes mechanism by which COVID-19 distribution in the body damages erythrocytes

Experts have investigated the mechanisms of COVID-19 inside-the-body distribution related to the damage of erythrocytes.

2 Nov 2020

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Study indicates underlying molecular sources in COVID-19 variability

Humans have different susceptibilities to SARS-CoV-2, and eventually develop varying degrees of fatigue, fever, and breathing problems.

26 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

UNM researchers identify medications that could help fight COVID-19 infection

University of New Mexico researchers who combed through a "library" of previously approved drugs believe they have identified a medication with the potential to help speed a patient's recovery from SARS-CoV-2 infection.

19 Oct 2020

Peptide therapy prevents overreaction of the immune system against infections

Individuals require enough action to remove offensive viruses or bacteria, but not so much that their body suffer a considerable damage.

15 Oct 2020

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

Extracellular vesicles (EVs) -- nanometer sized messengers that travel between cells to deliver cues and cargo -- are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury.