Phenotype News and Research

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NC State Researchers Develop New Method to Produce Seedless Plants

North Carolina State University researchers have successfully transferred an important gene from one compartment of a plant cell to another to produce tobacco plants that lack pollen and viable seeds, while otherwise growing normally.

19 Sep 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

Study Offers Key Insights into the Structure of Neutral Mutations

An unexpected link between pure mathematics and genetics has been disclosed by an interdisciplinary group of mathematicians, physicists, engineers, and medical scientists. This helps disclose deep knowledge of the structure of neutral mutations and also the evolution of organisms.

2 Aug 2023

A Common Diabetes Drug Helps Prevent Muscle Atrophy and Muscular Fibrosis

You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis-;which can help the elderly bounce back faster from injury or illness.

26 Jul 2023

Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

A high-fiber diet is known to have several health benefits. Scientific studies point to protection against such diseases as cancer and diabetes.

25 Jul 2023

USDA Funds Texas A&M AgriLife Research to Develop “Holy Grail” of Tomatoes

The U.S. Department of Agriculture has funded a new Texas A&M AgriLife Research project expected to bring researchers even closer to developing the "holy grail" of tomatoes.

7 Jul 2023

The Method by Which Plants Prevent Cracking Under Growth Stress

An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

23 Jun 2023

Searching Europe for Future-proof Oak Trees

Pedunculate, sessile and downy oaks are to be found throughout Europe, both on arid sites and on sites with a good water supply. The international ACORN research project is investigating the (genetic) adjustments shown by trees in dry sites in order to secure seed sources that can tolerate global warming for the oak forests of the future.

6 Jun 2023

New Toolbox Assists in the Understanding of Intricate Genetic Traits

Elizabeth King, Associate Professor in the Division of Biological Sciences at the University of Missouri, was inspired to spend her formative years studying science by a lifelong curiosity about the natural world and the diversity of life—and along the way, she discovered her passion for biology.

2 Jun 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Novel Map Depicts the Human Body's Highly Complicated System for Repairing DNA Damage

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

23 May 2023

Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation."

15 May 2023

Mutant MRTFB Proteins Associated With Novel Neurodevelopmental Disorder

Researchers at Baylor College of Medicine have linked specific variants or mutations of the gene myocardin-related transcription factor B (MRTFB) with a novel neurodevelopmental disorder.

10 May 2023

Genes Responsible for Aging Identified in Nematodes

The USask research team uncovered a pair of genes involved in removing cells of toxins that build in the body and cause aging while working with small nematode worms called C. elegans. The researchers discovered that inactivating genes named CCF-1 and PAL-1 caused nematodes to die 50% faster than usual.

3 May 2023

First Chronic Wound Murine Model to Profile the Effects of Cellular Senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

UH Researcher Designs New Model Expressing the Most Common Disease Mutation in USH2A

Usher syndrome, a rare inherited genetic disease, is a leading cause of combined deafness and blindness with type 2A (USH2A) being the most common form.

18 Apr 2023

New Tool can Help Untangle Genetic Factors Associated with Shared Characteristics Among Different Species

Aston University has worked with international partners to develop a software package to help scientists answer key questions about genetic factors associated with shared characteristics among different species.

17 Apr 2023