Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Mainz Biomed Announces Live Launch of ColoAlert® with Marylebone Laboratory in the United Kingdom

Mainz Biomed NV (“Mainz Biomed” or the “Company”), a molecular genetics diagnostic company specializing in the early detection of cancer, announced today that London-based Marylebone Laboratory (Marylebone Lab Ltd) has introduced ColoAlert®, Mainz Biomed’s flagship product—a highly effective and user-friendly at-home detection test for colorectal cancer (CRC) - to its extensive UK and international customer base.

2 Aug 2023

New Device Enables Real-Time Environmental Surveillance of SARS-CoV-2 Aerosols

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

11 Jul 2023

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Genetic variations, such as mutations, recombinations, or transpositions occur naturally in cultured microorganisms and are often considered nonneutral mutations.

7 Mar 2023

Effective and faster methodology detects RNA viruses based on the triplex-forming probe technology

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), the Institute of Microelectronics of Barcelona (IMB-CNM-CSIC) and the Aragon Nanoscience and Materials Institute of Aragon (INMA) -;a joint institute of the CSIC and the University of Zaragoza-; have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

28 Feb 2023

AutoPLP helps detect mutating pathogenic variants quickly and accurately

As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.

16 Feb 2023

Semi-quantitative system employs eDNA to detect endangered species

Alteration in river systems, overfishing, and the introduction of new, invasive species can all lead to a significant decrease in the number of native fish found in aquatic ecosystems.

8 Feb 2023

New scalable approach for the diagnosis of multiple respiratory viruses

Cambridge scientists have created a novel test that “fishes” for many respiratory viruses at once using single strands of DNA as “bait” and provides extremely accurate results in under an hour.

18 Jan 2023

Study highlights the history of ancient DNA technology development

Ancient DNA (aDNA) technology has been used for the past ten years by researchers working under the direction of FU Qiaomei at the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences (CAS) to learn more about the history of ancient human populations, particularly those in East Asia.

26 Jul 2022

Researchers review the major milestones of ancient DNA techniques

Ancient DNA (aDNA) technology has been used for the past ten years by researchers working under the direction of Qiaomei Fu at the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences (CAS) to learn more about the past of ancient human populations, particularly those in East Asia.

25 Jul 2022

Scientists discover new details on vital enzyme that allows for DNA sequencing

Researchers released a study in Sciences Advances that disclosed new facts about a critical enzyme that allows DNA sequencing.

16 Mar 2022

Sewer slime can accumulate SARS-CoV-2 RNA, study reports

During the COVID-19 pandemic, monitoring the levels of SARS-CoV-2 RNA in wastewater entering treatment plants has been one way that researchers have gauged the disease's spread.

10 Feb 2022

Study discovers new species of green microalga in São Paulo

A group led by researchers affiliated with the Phycology Laboratory at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have discovered a new species of green microalga in a reservoir located in the northwest of the state.

24 Nov 2021

Accurate diagnosis of bacterial superinfection pneumonia could help avoid antibiotic overuse

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

23 Aug 2021

New plasmofluidic chip could accelerate diagnosis during current and future pandemics

Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic.

27 May 2021

New method helps tests large groups for SARS-CoV-2 infection

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Telomere length decreases most rapidly from birth to age 3, shows study

Telomeres are protective caps on DNA that shorten as we grow older. Now, one of the first studies to examine telomere length (TL) in childhood finds that the initial setting of TL during prenatal development and in the first years of life may determine one's TL throughout childhood and potentially even into adulthood or older age.

25 May 2021

Environmental DNA helps track down species on the move

Many individuals would like to prevent sloughed-off skin and bodily fluids. However, for marine biologists like Cheryl Lewis Ames, Associate Professor of Applied Marine Biology in the Graduate School of Agricultural Science at Tohoku University (Japan), such life remnants have become a magical guide to detecting the unseen.

24 May 2021