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Researchers identify promising treatments for late-onset Alzheimer’s disease

Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).

25 Nov 2020

Unique experiment shows how corals manage deoxygenation stress

Oxygen is life, in or out of the water, raising concerns that declining ocean oxygen stores are adding an additional environmental stress to already highly vulnerable coral reef ecosystems.

17 Nov 2020

Teratomas could provide a new glance at human development

Finding just the right model to study human development--from the early embryonic stage onward--has been a challenge for scientists over the last decade.

5 Nov 2020

Study shows genetic analysis with RNA sequencing can increase diagnostic yield

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis.

28 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Genetic factor enables regeneration of adult skin like a newborn's

A newly identified genetic factor allows adult skin to repair itself like the skin of a newborn babe. The discovery by Washington State University researchers has implications for better skin wound treatment as well as preventing some of the aging process in skin.

30 Sep 2020

Analysis of wild tomatoes elucidates genetic basis underlying fruit traits

Domestication and subsequent intensive breeding of tomato had a major impact on fruit ripening and the myriad metabolic processes accompanying it.

29 Sep 2020

Computational model effectively identifies genetic mutations in breast tumors

Researchers at Lund University in Sweden have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumors. The study, the largest of its kind in the world, includes results from over 3 200 patients with breast cancer.

25 Sep 2020

Study reveals a successful strategy to fight influenza

For a long time, influenza scientists have largely focused their studies on the epithelial cells that line the lungs.

2 Sep 2020

Study reveals new strategy to reduce tumor growth

According to a new study, tumors can escape the immune system by instructing immune cells to create immunosuppressive steroids.

31 Jul 2020

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

A research team from the HSE University has designed innovative methods for controlling the expression of TMPRSS2 and ACE2 enzymes.

30 Jul 2020

New study shows how T cells function in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

27 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Disseminated cancer cells hijack crucial iron micronutrients to survive

In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.

17 Jul 2020

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

10 Jul 2020