Rheumatoid Arthritis News and Research

RSS

Rheumatoid arthritis (RA) is a chronic disease of the joints that can cause a disabling degree of pain and significantly interfere with an individual’s day-to-day living.

Using in vivo self-assembled siRNA as part of combination therapy for ulcerative colitis

There is still a large unmet medical need for the treatment of ulcerative colitis, despite recent improvements in the understanding of the pathogenic mechanisms of ulcerative colitis.

30 Sep 2022

Microbiomes can help cure food allergies in mice

Many people with dietary allergies may have minor symptoms when they consume foods that trigger them, but for some, the consequences could be lethal. In lab experiments, a bacterial chemical called butyrate produced by healthy microbiomes has shown promise in preventing allergy reactions, but it is unpleasant to consume.

23 Aug 2022

Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Study reveals genetic architecture of COVID-19 risk factors and disease complications

According to a recent study of information from the Veterans Affairs Million Veteran Program, there are genetic correlations between COVID-19 severity and specific medical disorders that are established risk factors for severe COVID-19.

3 May 2022

Zbtb38 removal results in early embryonic death

DNA methylation is a critical epigenetic alteration for mammalian development.

20 Apr 2022

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.

2 Mar 2022

Central signaling pathway likely to help reduce the progression of autoimmune disorders

When the immune system fails and assaults the body’s own components, autoimmune disorders develop.

25 Feb 2022

Study findings open new avenues for research into host-directed therapies for TB

A*STAR’s GIS and ID Labs have discovered KCNJ15, a gene linked to the human immune system’s ability to combat TB and maybe other infectious diseases.

18 Feb 2022

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

8 Nov 2021

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response.

27 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Research shows how dendrimers avoid detection by the immune system

Tiny synthetic particles known as dendrimers have been shown to avoid detection by our immune system and so could be used to develop a new system to deliver drugs into the body without triggering a reaction.

3 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

NYU Tandon professors show broad therapeutic potential of novel peptide to combat multiple diseases

NYU Tandon professors Mary Cowman and Jin Ryoun Kim recently published a paper describing a novel peptide with broad therapeutic potential to combat chronic inflammation in multiple diseases.

From New York University (NYU) 31 Aug 2021

Study employs llama nanobodies to hunt human cytomegalovirus

Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.

26 Jul 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

New study assesses total economic impact of human genomics

Human genetics and genomifefcs contributed $265 billion to the U.S. economy in 2019 and has the potential to drive significant further growth given major new areas of application, according to a new report issued today by the American Society of Human Genetics (ASHG).

19 May 2021