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HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Specific gene variant linked with poor response to sublingual immunotherapy for allergies

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30% of patients don’t respond to SLIT for Japanese cedar pollinosis–a highly common disease.

8 Mar 2022

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Cedars-Sinai scientists discovered that attacking a protein present in prostate cancer cells could stop the disease from further spreading to various other parts of the body.

2 Mar 2022

Ether anesthetics can prevent touch-induced trigger in the carnivorous Venus flytrap

Medicine has a broad repertoire of anesthetics at its medication allows patients to better endure painful treatments or even sleep through them.

22 Feb 2022

Experts identify critical genes that cause coronary heart disease and trigger heart attacks

Recent research identified the major genes involved in coronary heart disease and cardiac arrest.

21 Feb 2022

MIT researchers create a new cerebrovasculature atlas

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

16 Feb 2022

Mortality of newborns on ECMO linked with red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

15 Feb 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Researchers have explored the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, and breast cancer.

31 Jan 2022

Novel technology combats cancer more quickly and efficiently

Researchers have created a new technology that allows them to use immune cells from tumors to combat cancer more quickly and efficiently.

31 Jan 2022

Researchers catalog the complete cells that form the blood vessels of the human brain

Researchers at UC San Francisco have cataloged all of the cells that make up the blood vessels in the human brain, as well as their positions and the genes produced.

31 Jan 2022

Scientists discover families of proteins that could predict organ transplant rejection

Northwestern University scientists have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care.

28 Jan 2022

IL-6 regulates cartilage regeneration in joints and growth plates, says study

The IL-6 protein family has a poor reputation for promoting inflammation, arthritis, autoimmune disease, and even cancer.

20 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Heart disease continues to be a leading cause of mortality and morbidity across the globe. Positron emission tomography (PET) has slowly become a remarkable technology of a non-invasive technique for accurately diagnosing cardiac diseases.

11 Jan 2022

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Surgery News and Research

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

Specific gene variant linked with poor response to sublingual immunotherapy for allergies

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Ether anesthetics can prevent touch-induced trigger in the carnivorous Venus flytrap

Experts identify critical genes that cause coronary heart disease and trigger heart attacks

MIT researchers create a new cerebrovasculature atlas

Mortality of newborns on ECMO linked with red blood cell transfusion volume

New method helps distinguish bacterial DNA from human and other non-bacterial cells

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Novel technology combats cancer more quickly and efficiently

Researchers catalog the complete cells that form the blood vessels of the human brain

Scientists discover families of proteins that could predict organ transplant rejection

IL-6 regulates cartilage regeneration in joints and growth plates, says study

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Changes in the activity of gene networks may explain arteriosclerosis risk

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

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