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Role of Inhibitory Interneurons in Memory Expression

Memory, a crucial aspect of human survival, is intricately connected to how humans encode, retrieve, and react to external stimuli.

9 Nov 2023

Dendritic Cells Reprogram Their Genes to Enhance Immune Response

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), under the leadership of Professor Francisco Sánchez-Madrid, have discovered that dendritic cells, responsible for triggering targeted immune responses, possess the ability to modify their genes in order to enhance their immune reactivity.

6 Nov 2023

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier.

30 Aug 2023

Noelin Proteins’ Key Role in Strengthening Neuronal Signals

As per a research study in mice from the National Eye Institute (NEI) and the University of Freiberg, Germany, the Noelin family belonging to secreted proteins bind to the exterior part of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane.

17 Aug 2023

Scientists Discover the Mechanisms of Synaptic Pruning in Brain Development

Researchers at Kyushu University have uncovered the mechanisms of a fundamental yet critically under-looked phase in brain development: synaptic pruning.

8 Jun 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.

5 May 2023

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

15 Feb 2023

Employing molecular anchor for more effective CAR immunotherapies

Researchers at St. Jude Children’s Research Hospital discovered that immune cells with the attached protein boosted the killing of cancer, irrespective of the kind of cancer cell or the type of cancer being targeted.

3 Feb 2023

UO research in zebrafish shows a gut-brain link that influences social behavior

To learn to socialize, zebrafish need to trust their gut. Gut microbes encourage specialized cells to prune back extra connections in brain circuits that control social behavior, new UO research in zebrafish shows.

10 Nov 2022

Many proteins share important roles in the formation and function of synapses, study finds

Not just three, but even five proteins share important roles in the formation and function of synapses and can substitute for each other. This discovery was made by a team of the research focus "Mental Health & Neuroscience" of the Karl Landsteiner University of Health Sciences Krems (KL Krems) and the CavX PhD program of the Medical University of Innsbruck.

26 Oct 2022

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Principal researchers at the Brain Science Institute (BSI) of the Korea Institute of Science and Technology were said to have discovered substantially decreased activity of focal adhesion kinase (FAK) proteins that play a significant role in neurite motility and proper synapse formation in HD patients’ brain tissues.

19 Sep 2022

Synapse News and Research

Role of Inhibitory Interneurons in Memory Expression

Dendritic Cells Reprogram Their Genes to Enhance Immune Response

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Noelin Proteins’ Key Role in Strengthening Neuronal Signals

Scientists Discover the Mechanisms of Synaptic Pruning in Brain Development

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Employing molecular anchor for more effective CAR immunotherapies

UO research in zebrafish shows a gut-brain link that influences social behavior

Many proteins share important roles in the formation and function of synapses, study finds

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Characterizing the transcription profile of microglia in a mouse model

Research reveals how two RNA-binding proteins interact with each other

Study reveals possibility of changing the identity of synapses through enzymatic means

Researchers determine small protein’s structure, likely to pave the way for advanced treatments

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Researchers discover how new techniques may alter the synaptic connection of neurons

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

The Exclusome, A New Mammalian "Containter"

Breaking Down the Onso System: PacBio's Genomic Advancement

The Last Piece of Our Genome: Sequencing the Y Chromosome

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