A virus is a microscopic infectious agent that can reproduce only inside a host cell. Viruses infect all types of organisms: from animals and plants, to bacteria and archaea. Since the initial discovery of tobacco mosaic virus by Martinus Beijerinck in 1898, more than 5,000 types of virus have been described in detail, although most types of virus remain undiscovered. Viruses are ubiquitous, as they are found in almost every ecosystem on Earth, and are the most abundant type of biological entity on the planet. The study of viruses is known as virology, and is a branch of microbiology.
A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.
An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.
But there is still an opportunity to substantially reduce the death toll by prioritizing the most critical services, specifically antiretroviral therapy for HIV, timely TB diagnosis and treatment, and provision of long-lasting insecticide-treated nets for malaria, researchers say.
An adenovirus infection can be potentially life-threatening, especially for children after a stem cell transplant.
An analysis of nearly 300 recently identified human SARS-CoV-2 antibodies uncovered a gene frequently used in antibodies that most effectively target the virus. The results contribute to growing structural insight that will be needed for successful vaccine development against SARS-CoV-2.
By studying fifty COVID-19 patients, researchers in France identified a unique signature - a combination of deficiency in a response of a particular interferon, as well as exacerbated inflammation - in the most critically ill.
A single dose of the flu drug baloxavir marboxil can reduce the spread of the illness within households, new research concludes.
Frogs and toads are green for a very good reason - it makes them harder to see in their leafy environments. Good camouflage allows them to eat and not be eaten. But not all frogs have arrived at this life-saving greenness in the same way.
Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.
A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.
Human papilloma viruses (HPVs) - a common group of viruses known to cause cervical cancers - may also have a causal role in prostate cancer, according to a literature review published in the open access journal Infectious Agents and Cancer, supporting the case for universal HPV vaccination.
A new antiviral drug that is effective against a broad range of human pathogens in the paramyxovirus family, such as the human parainfluenzaviruses and measles virus, has been discovered by researchers in the Institute for Biomedical Sciences at Georgia State University.
Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.
Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.
The CRISPR gene editing system is a robust tool specifically developed for the targeted editing of genomes. While this tool has considerable therapeutic potential, it is associated with improper editing of “off-target” sites.
Researchers at the Francis Crick Institute have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.
Porvair Sciences reports on the Vyon porous plastic filters it is supplying to University of Cambridge spinout company - Diagnostics for the Real World for their game-changing SAMBA II machine that provides diagnosis of COVID-19 infection in under 90 minutes.
Scientists have created a human cell “membrane on a chip” that enables tracking of the interaction of drugs and infectious agents with the human cells.
Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.
More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.