A virus is a microscopic infectious agent that can reproduce only inside a host cell. Viruses infect all types of organisms: from animals and plants, to bacteria and archaea. Since the initial discovery of tobacco mosaic virus by Martinus Beijerinck in 1898, more than 5,000 types of virus have been described in detail, although most types of virus remain undiscovered. Viruses are ubiquitous, as they are found in almost every ecosystem on Earth, and are the most abundant type of biological entity on the planet. The study of viruses is known as virology, and is a branch of microbiology.
Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.
Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.
SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.
Natto is a fermented soybean dish usually served by the Japanese for breakfast. Although it actually originated at the turn of the last millennium, it could be the key to a modern problem—COVID-19—reports a new cell-culture-based study.
SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.
A research team has demonstrated that the L452R mutation of the SARS-CoV-2 spike protein plays a role in cellular immunity evasion.
Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.
Japanese researchers have come up with a highly accurate, rapid test for identifying antibodies against the SARS-CoV-2 spike protein in human serum.
Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.
Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.
The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.
Immunologists have discovered a molecular route that regulates how crucial immune cells evolve into the immune system’s functioning components.
Since the start of the COVID-19 epidemic, proteins have been stealthily taking over human lives.
Researchers have identified how mutations on the SARS-CoV-2 spike protein separately create variants that are potentially resistant to antibodies.
An international research team, jointly headed by the University of Adelaide and the University of Arizona, has examined the genomes of over 2,500 modern humans from 26 global populations to gain a better understanding of people’s adaptations to the historical outbreaks of coronavirus.
A team of researchers from the University of California - Davis Health (UC Davis) has made a breakthrough discovery of a unique type of stem cell that reduces the amount of the virus that causes AIDS.
Long COVID symptoms, such as weariness, brain fog, and rashes, may be caused by Epstein-Barr virus (EBV) reactivation because of the inflammatory response to coronavirus infection, which occurs in about 30% of individuals following recovery from initial COVID-19 infection.
According to researchers from Harvard T.H. Chan School of Public Health and MIT, the use of genome-wide association studies (GWAS) methodology to assess whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can help identify highly pathogenic variants of the virus that should be flagged for containment.
Looking for a new strategy in the long-running battle against the SARS-CoV-2 virus, researchers have developed nanobodies.
A research team has successfully built a model of lung cells that can be used to simulate how COVID-19 infects the airways.