therapeutics News and Research

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New method could create a promising vehicle for vaccine delivery against SARS-CoV-2

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

14 Mar 2022

Improving the long-term effectiveness of TB vaccine in mice

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

14 Mar 2022

Orbit Discovery and WuXi AppTec sign agreement to access peptide discovery and optimisation technologies

Orbit Discovery is pleased to announce the commencement of a partnership with WuXi AppTec, a leading global provider of R&D and manufacturing services.

8 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Several variants of COVID-19 may hide away from body’s immune system, new study reveals

A recent study published in Nature Communications by an international research group suggests that people infected with COVID-19 may have several distinct SARS-CoV-2 variants stashed away from the immune system in various parts of the body.

3 Mar 2022

UH researcher secures $2 million to develop drugs for formerly undruggable cancer targets

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas, a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer.

3 Mar 2022

Researchers describe the structural basis of how antibodies may neutralize SARS-CoV-2 variants

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

2 Mar 2022

Macrophages restore normal functions when transported back to the body, says research

New research shows that some immune cells could reinstate their regular functions when they are introduced back into the body.

28 Feb 2022

New computational tool simulates evolution

The building blocks of life-saving therapeutics could be developed in days instead of years thanks to new software that simulates evolution.

25 Feb 2022

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections.

18 Feb 2022

CNIO researchers design new platform to test drugs for possible use in brain metastases

It is estimated that about a quarter of cancer patients are at risk of brain metastases, a rate that is increasing especially among those who suffer relapses after having undergone different cancer treatments.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

MIT researchers create a new cerebrovasculature atlas

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

16 Feb 2022

Human nose organoids reveal the first events of SARS-CoV-2 and RSV infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

Plant-based nanoparticles likely to provide anti-cancer drug

Nanomaterials have transformed cancer therapy, and plant-derived nanoparticles have the added benefit of being cost-effective and simple to produce in mass.

From Tokyo University of Science 16 Feb 2022

Tropical sea anemone stings could hold key to new pain-relieving drugs

QUT PhD researcher Lauren Ashwood has studied sea anemones' venom makeup extensively, in particular, Telmatactis stephensoni a reef-based sea anemone that can grow from 8 to 10 cm.

8 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.