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New Genetic Rules Guide Killer T Cell Fate

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune cells-known as CD8 killer T cells-choose between becoming long-lasting, protective defenders or slipping into exhausted, dysfunctional states.

6 Feb 2026

Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

New Map Reveals How Cancer Gene Mutations Influence Tumor Growth

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth.

3 Feb 2026

Unusual DNA Structure i-DNA Linked to Cancer Regulation

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes.

3 Feb 2026

Brain's Aging Waste System Linked to Synapse Loss and Cognitive Decline

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

3 Feb 2026

Novel RNA Molecule Preserves Cell Structure, Impacts Cancer Survival

In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA molecule that plays a crucial role in preserving the integrity of a key cellular structure, nucleolus (a dense region of the cell containing a subset of crucial genetic material).

3 Feb 2026

Study Uncovers a Crucial Factor to Improve Treatment for Glioblastoma

A groundbreaking study from Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer.

2 Feb 2026

Human Neurons Reveal Why Some Cells Resist Tau Protein Buildup

New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient than others to the buildup of a toxic protein that is a hallmark of Alzheimer's disease and related dementias, potentially leading to new targets for therapies or treatments.

31 Jan 2026

Ancient DNA Reveals Rare Growth Disorder in Upper Paleolithic Individuals

Researchers led by the University of Vienna and Liège University Hospital Centre have identified genetic variants associated with a rare inherited growth disorder in two prehistoric individuals who lived more than 12,000 years ago.

30 Jan 2026

Autism-Linked Mutations Converge on Shared Early Brain Pathways

UCLA Health researchers have created a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development, providing new insights into the ways diverse genetic causes may lead to shared features and symptoms of the disorder.

29 Jan 2026

Cellular Garbage Collector Shields Neurons From Alzheimer’s Damage

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

29 Jan 2026

Advanced 3D Tumor Organoids Reveal How Glioblastoma Responds to Immunotherapy

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

28 Jan 2026

Blood protein test helps spot hidden cancers in patients with vague symptoms

Plasma protein profiling offers a promising tool for cancer risk stratification in patients with non-specific symptoms, potentially reducing diagnostic delays.

28 Jan 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

MYC Gene's Dual Role in Cancer Growth and Immune Suppression

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

24 Jan 2026

Rare EBV-Driven B Cell Event May Spark Multiple Sclerosis Onset

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026