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Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

MYC Gene's Dual Role in Cancer Growth and Immune Suppression

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

24 Jan 2026

Rare EBV-Driven B Cell Event May Spark Multiple Sclerosis Onset

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026

Genetic Study Links Expanding DNA Repeats to Aging and Disease Risk

An analysis of genetic data from over 900,000 people shows that certain stretches of DNA, made up of short sequences repeated over and over, become longer and more unstable as we age.

8 Jan 2026

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

8 Jan 2026

MD Anderson and SOPHiA GENETICS Partner to Advance AI-Driven Cancer Care

The University of Texas MD Anderson Cancer Center and SOPHiA GENETICS today announced a strategic collaboration that unites SOPHiA GENETICS' AI-powered analytics with MD Anderson's clinical and scientific expertise to accelerate data-driven cancer care through new tools that can accurately analyze, interpret and translate diagnostic results into clinical practice.

8 Jan 2026

Mitochondria Transfer Eases Chronic Nerve Pain

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

8 Jan 2026

Dual Genetic Mutations Drive RNA Mis-Splicing and Leukemia Progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic mutations – IDH2 and SRSF2 – work cooperatively to mis-splice RNA messages and change how blood cells develop.

6 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

LINE-1 Retrotransposons Reshape Cancer Genome Architecture

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

6 Jan 2026

Tumor Bacteria Found to Drive Immunotherapy Resistance

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

5 Jan 2026

Interferon Response in Female Brains Linked to Alzheimer's Progression

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

Homer1 Gene Plays a Critical Role in Shaping Attention

Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise.

26 Dec 2025

Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

24 Dec 2025

UT Southwestern Researchers Design Tau Protein to Combat Neurodegenerative Diseases

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies. These findings, reported in Structure, could lead to new treatments for conditions including Alzheimer's disease, frontotemporal dementia, chronic traumatic encephalopathy (CTE), and progressive supranuclear palsy.

24 Dec 2025