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Disarming Cancer’s Droplet Hubs to Halt Tumor Growth

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Serotonin-Producing Gut Microbes May Hold the Key to Treating IBS

Research from the University of Gothenburg, Sweden, clarifies the complex interaction between gut bacteria and IBS.

21 Oct 2025

Leptin-Sensitive Brain Circuit Helps Overcome Anxiety to Perform Essential Behaviors

How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the lateral hypothalamus that helps to overcome anxiety to perform essential behaviors such as exploring, feeding, and limiting maladaptive hyperactivity.

21 Oct 2025

Cancer Reawakens Embryonic Gene Editors to Fuel Tumor Growth

Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks the proteins, or "editors", that control how those genes are read.

17 Oct 2025

Cellular Switches Direct Supplies During Memory Formation

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections.

15 Oct 2025

New Insights into rRNA Motifs and Nervous System Genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

15 Oct 2025

GlyTR Therapeutics Unveils Groundbreaking Glycan-Targeting Cancer Immunotherapy

GlyTR Therapeutics, a biotech company pioneering development of glycan-targeting cancer immunotherapies, announced the publication of its foundational technology in the journal, Cell.

14 Oct 2025

Developing GoT-Multi to Track Cancer Evolution and Treatment Resistance

A novel tool created by researchers at Weill Cornell Medicine and the University of Adelaide has improved the capacity to monitor multiple gene mutations while concurrently recording gene activity in individual cancer cells.

13 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

New Genetic Insights Offer Hope for Early Detection of Osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

10 Oct 2025

Genomic-First Approach Offers Potential for Earlier Diagnosis of Rare Disorders

A "genomic-first" approach to screening for rare genetic disorders -identifying specific genetic variants and then studying associated traits and symptoms - can identify these conditions earlier and more frequently than standard genetic testing driven by clinical symptoms, a Geisinger study found.

8 Oct 2025

Multiple Genetic Changes Play Key Role in the Development of Complex Disorders

The genetic roots of a disease or disorder do not always grow into clear cut, easily diagnosed clinical features.

8 Oct 2025

EZH2 Inhibition Restores Order in Cancer Cell Division and Reduces Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading.

6 Oct 2025

How GBA Mutations Drive Cognitive Decline in Parkinson's Disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain.

3 Oct 2025

Actin Scaffold Protects Cancer Cell Nuclei Under Mechanical Stress

Researchers from the Cluster of Excellence CIBSS have demonstrated that an actin scaffold stabilizes the cell nucleus upon mechanical stress.

30 Sep 2025

Protein Networks Expose New Therapeutic Targets for Alzheimer's

A recent study conducted by the Icahn School of Medicine at Mount Sinai provides one of the most thorough insights to date regarding the interactions of brain cells in Alzheimer’s disease, illustrating protein networks that expose communication breakdowns and highlight potential new therapeutic avenues for treatment.

26 Sep 2025

Breakthrough in Treating Age-Related Macular Degeneration with Retinal Stem Cells

In the United States, age-related macular degeneration is a leading cause of irreversible vision loss in people who are 60 and older.

24 Sep 2025

Targeting Two Key Proteins to Weaken Pancreatic Cancer's Defenses

Indiana University School of Medicine scientists have identified a new way to weaken pancreatic cancer's defenses by targeting two key proteins that help the deadly disease resist treatment.

22 Sep 2025

Alpha Cells may Produce More Bioactive GLP-1 Than Previously Believed

A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation - and pointing to a surprising new ally in the fight against type 2 diabetes.

22 Sep 2025

Study Uncovers How Cell Clustering Affects Glioblastoma Aggressiveness

A new study, led by researchers at Sylvester Comprehensive Cancer Center part of the University of Miami Miller School of Medicine, captured details of glioblastoma that had never before been seen and revealed a surprise finding: Glioblastoma cells that "cluster" together with other cells of the same type are less deadly than those that disperse from these clusters.

22 Sep 2025