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Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

Neutrophil Activation by NMU Blocks Cytotoxic T Cell Tumor Infiltration

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

26 Sep 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown pathway that prostate tumors leverage to suppress the immune system by reshaping the tumor microenvironment to resist treatment.

25 Sep 2026

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

A world-first test developed by researchers at the Garvan Institute of Medical Research has identified the genetic cause of inherited muscle disease in people who remained without answers after years, sometimes decades, of standard testing.

25 Sep 2026

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

What we see appears stable, even though neuronal activity is full of irregular fluctuations. A team led by Dr Mehdi Borjkhani from ICTER has shown, using a minimal model of the primary visual cortex, that two natural feedback mechanisms can constrain chaos and reduce variability in neural activity by up to 93 percent.

23 Sep 2026

New Screening Program Increases Detection of Congenital Cytomegalovirus in Newborns

Researchers at Cleveland Clinic Children's have developed a new screening program for congenital cytomegalovirus, the most common infection passed from mothers to babies during pregnancy.

23 Sep 2026

Strength Training Induces Fat Breakdown in Obese Mice Without Weight Loss

Just seven days of strength training increased visceral fat burning in obese mice, even before any weight loss could be seen on a scale. In an experiment conducted at the State University of Campinas (UNICAMP), researchers observed that a short period of strength training activated mechanisms involved in fat breakdown, reduced fat cell size, and decreased fat around the animals' intestines.

23 Sep 2026

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

Alzheimer's disease and related neurodegenerative disorders are among medicine's most challenging conditions, progressively impairing memory, movement and independence. Now, researchers at the University of California San Diego School of Medicine have identified a naturally occurring peptide - a small protein fragment called catestatin (CST) - that may help counter several key processes driving neurodegeneration.

23 Sep 2026

UCLA Team Develops Advanced Immunotherapy to Fight Dangerous Arterial Plaques

A UCLA research team has engineered a new type of immune cell that attacks atherosclerotic plaques — the fatty buildup inside artery walls that drives most heart attacks and strokes.

23 Sep 2026

Antidepressant Withdrawal, Not Relapse, Linked to Mood Changes

When people stop taking antidepressants they can feel terrible – their mood can plummet and anxiety can spike.

22 Sep 2026

Tumor Suppressor Pathways Remain Intact but Hyperactive During Progressive Tissue Aging

A new review was published in Volume 18 of Aging on August 31, 2026, titled "The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework."

22 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Stay Sharp After Menopause: How Aerobic Exercise Can Improve Key Thinking Skills

Regular aerobic exercise – the kind that gets your heart pumping – can improve important thinking skills called executive functions, and the benefits appear especially strong for women after menopause, according to Rutgers researchers.

18 Sep 2026

Groundbreaking ARUP Research Clarifies Clinical Value of Atypical Cell-Free DNA Screening Results

An extensive, first-of-its-kind research study by ARUP Laboratories clarifies the clinical value of atypical findings from prenatal cell-free DNA (cfDNA) screening and their impact on pregnancy outcomes.

18 Sep 2026

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Stem cell researchers have identified inflammatory pathways that may play a key role in driving kidney damage in diabetic kidney disease (DKD), pointing to potential new approaches for protecting the kidneys.

18 Sep 2026

Researchers Reveal How p53 Tumor-Suppressor Protein Hide From T Cells

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

18 Sep 2026

Uncovering B Cell Signaling Pathways to Enhance Targeted T Cell Immunotherapies

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026

Medical Condition News

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

Neutrophil Activation by NMU Blocks Cytotoxic T Cell Tumor Infiltration

Chronic Inflammation Linked to Heart Changes and Risks

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

New Screening Program Increases Detection of Congenital Cytomegalovirus in Newborns

Strength Training Induces Fat Breakdown in Obese Mice Without Weight Loss

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

UCLA Team Develops Advanced Immunotherapy to Fight Dangerous Arterial Plaques

Antidepressant Withdrawal, Not Relapse, Linked to Mood Changes

Tumor Suppressor Pathways Remain Intact but Hyperactive During Progressive Tissue Aging

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

Stay Sharp After Menopause: How Aerobic Exercise Can Improve Key Thinking Skills

Groundbreaking ARUP Research Clarifies Clinical Value of Atypical Cell-Free DNA Screening Results

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Researchers Reveal How p53 Tumor-Suppressor Protein Hide From T Cells

Uncovering B Cell Signaling Pathways to Enhance Targeted T Cell Immunotherapies

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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