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New Method Reveals Genome Changes and Activity in Cancer

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer.

9 Apr 2026

Study Reveals Pol Theta Role in Cancer DNA Repair

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

8 Apr 2026

Largest African Genomic Study Reveals New Kidney Disease Insights

An international research collaboration led by the University of the Witwatersrand and Queen Mary University of London has published the most comprehensive genomic investigation of kidney function ever conducted in African populations, shedding new light on the genetics of chronic kidney disease (CKD) across diverse African populations.

8 Apr 2026

ASHOP Platform Unifies Multi-Omics Data for Blood Cancer Insights

Scientists at St. Jude Children's Research Hospital, the American Society for Hematology (ASH) and the Munich Leukemia Laboratory have developed a data-sharing platform that unites genomics, gene expression and clinical information from nearly 6,000 patients with blood cancers.

7 Apr 2026

New Mouse Model Reveals Viral Path to Liver Cancer

Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease unfolds in people, from initial infection with a virus to liver inflammation, scarring, and cancer.

7 Apr 2026

Breakthrough Platform Could Accelerate Therapeutic Development for Mitochondrial Disorders

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

7 Apr 2026

3D Microfluidic Tumor Model Reveals How High-Fat Diets Promote Invasive Cancer

Princeton researchers have revealed new links between high-fat diets and aggressive breast cancer, demonstrating the important role fat plays in making some cancers more invasive.

7 Apr 2026

Study Maps Cellular Pathways Essential for Metaplasia and Precancerous Lesions in the Pancreas

Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate.

6 Apr 2026

Study Highlights Unexpected Role of Stard7 in Colorectal Cancer Development

A new study led by researchers at the University of Liège highlights the unexpected role of Stard7 in the development of intestinal cancers.

3 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Defining Tumor Microbiota for Improved Cancer Diagnosis and Treatment

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

3 Apr 2026

New Framework Prioritizes Uncertain Genetic Variants in Cancer Profiling

Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling (CGP) of cancers.

1 Apr 2026

Cysteine Pathways Shape T Cell Expansion and Cancer Defense

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

1 Apr 2026

Mirror Protein Design Blocks Amyloid Beta in Alzheimer’s Disease

Understanding how proteins interact with their own mirror images enabled a Kobe University research team to design a small mirror protein that disables a causal factor of Alzheimer's disease, amyloid-beta.

1 Apr 2026

Novel Immunotherapy Disrupts the Protective Tumor Microenvironment Ecosystem

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: tumor cells often don't share one consistent surface target, and many solid tumors are protected by a dense network of scar tissue and immune-suppressive cells that blocks T cells.

31 Mar 2026

Autism-Associated Genes are Largely the Same Across Different Global Ancestries

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ancestries.

31 Mar 2026

New Genetic Pathways and Compounds Identified to Prevent Cone Degeneration

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

30 Mar 2026

New Platform Models Cancer Metastasis and Cell Cluster Survival

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

28 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026

SHP Protein Slows Cartilage Degeneration in Osteoarthritis

Osteoarthritis, a condition that causes pain and reduced mobility in joints such as the knees and fingers, is one of the most common joint disorders worldwide, particularly among aging populations.

24 Mar 2026