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Salk Institute Decodes Molecular Timeline of Age-Related Neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide.

26 Jun 2026

Open-Source Genomic Tool Accelerates Diagnoses for Rare Diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

26 Jun 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Targeting Fibroblast Communication Could Halt Primary Sjögren Disease Damage

In autoimmune disorders, immune cells targeting 'self' proteins are mistakenly activated, resulting in their abnormal expansion and responsiveness. It has been known to reduce the quality of life of patients over a prolonged period.

25 Jun 2026

Global Study Identifies Robust Gut Microbiome Signature in Colorectal Cancer

Researchers have long suspected that the gut microbiome – the community of bacteria and other microorganisms living in the intestine – is closely linked to colorectal cancer.

25 Jun 2026

Novel Cellular Discoveries Offer New Potential Treatment Strategies for Arthritis

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies.

25 Jun 2026

Common Genetic Variant Increases Colorectal Cancer Risks for General Population

A team of scientists from the Barbara Ann Karmanos Cancer Institute, Wayne State University, and institutions across the U.S., have published a landmark paper on the role of TGFBR1*6A, a naturally occurring genetic mutation in the TGFBR1 gene found in approximately 14 percent of the general population.

24 Jun 2026

Immune Pathway Breakthrough Reveals Critical Sex Differences in Female Glioblastoma

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

24 Jun 2026

Scientists Move Beyond Individual Genes to Decode Schizophrenia’s Complex Genetic Network

Scientists have long known that schizophrenia runs in families, but pinpointing exactly which genes contribute to risk has been like searching for needles in a haystack. Now, researchers at the Lieber Institute for Brain Development and a consortium of collaborators from the University of Bari, Italy, and over 60 psychiatric hospitals all over the world, have developed a groundbreaking approach that looks beyond individual genes.

23 Jun 2026

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

23 Jun 2026

Penn Study Uses AI to Discover Prion-Based Antibiotics

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

22 Jun 2026

Targeting Iron Metabolism Offers a New Strategy to Kill Cancer Cells

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a key metabolic pathway that allows colorectal cancer cells to accumulate large quantities of iron. Blocking that pathway reduced iron levels and caused the cancer cells to die.

22 Jun 2026

New Research Examines How Blood Cancer Mutations Progress from Healthy States

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in development of the disease. The work provides insight into the initial phases of the disease and may eventually lead to tailored monitoring techniques that improve patient outcomes.

22 Jun 2026

Single-Cell Analysis Uncovers How Cancer Tumors Diversify and Resist Treatment

A comprehensive multi-cancer study from researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core genetic changes that can be traced back to a common ancestral cell, providing a single-cell view of how tumors adapt, survive and diversify. Understanding this helps explain why some cancer cells manage to survive treatments, paving the way for more tailored diagnostic and therapeutic strategies.

22 Jun 2026