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Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Researchers Explain How a Single Mutation Causes Ataxia

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control.

4 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Previously unknown telomere and cancer connection to the immune system revealed

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

31 Mar 2023

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

31 Mar 2023

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Study expands understanding of PAK1-related IDDMSSD

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

30 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

29 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

A new research paper was published in Genes & Cancer on March 10, 2023, entitled, "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer."

27 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Using big data and machine learning to create multi-functional cancer drugs

Many cancer patients undergo treatment with multiple drugs, each of which attacks cancer in a different way, so the combination fights cancer on many fronts. But more drugs mean higher risks of side effects.

24 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Medical Condition News

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Researchers Explain How a Single Mutation Causes Ataxia

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

Previously unknown telomere and cancer connection to the immune system revealed

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Study expands understanding of PAK1-related IDDMSSD

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

Innovative new approach to constructing a nose in young patients with arhinia

Using big data and machine learning to create multi-functional cancer drugs

Common Epstein-Barr virus may be a trigger for multiple sclerosis

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Blunted inflammatory response in obese individuals responsible for susceptibility to severe COVID-19

Study identifies 238 amyloid toxicity protective or activator genes

BetaLife and A*STAR team up to accelerate the development of new cell-based therapy for diabetes

New study pinpoints key source of T cell "exhaustion"

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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