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Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

10 Jun 2025

Distinct Neural Patterns Reveal How Mice Navigate Ambiguous Landmarks

When navigating a place that we're only somewhat familiar with, we often rely on unique landmarks to help make our way.

9 Jun 2025

Zebrafish Model Offers Hope for Treating Ultra-Rare Muscle Disease

Can a small fish help identify possible treatments for an ultra-rare inherited disease found in an Alabama boy? The genetic disease is XMEA, which progressively weakens the muscles and can affect the liver and heart.

6 Jun 2025

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

Yale Researchers Identify Gut-Linked Immune Cells in the Brain

Yale School of Medicine researchers have discovered, for the first time, specialized immune cells in the brains of mice and humans which may facilitate communication between the gut and brain.

29 May 2025

Gut Microbiome Offers Clues to Detecting and Treating Gastrointestinal Diseases

Scientists have discovered a range of 'biomarkers' that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).

29 May 2025

Seasonal Light Changes Continue to Shape Human Circadian Rhythms

It’s tempting to think that, with our fancy electric lights and indoor bedrooms, humanity has evolved beyond the natural influence of sunlight when it comes to our sleep routines.

29 May 2025

New Stem Cell Islet Model Mimics Pancreatic Function More Accurately

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

24 May 2025

Liver Energy Storage Tied to Genetic Activity in PPP1R3B

A new study published in Science Advances reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes.

19 May 2025

Skin Microbiome Found to Help Regulate Immune Response to UV Radiation

The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase.

14 May 2025

Learning Reshapes Brain Wiring Through Thalamocortical Pathways

A landmark study published by scientists at the University of California San Diego is redefining science's understanding of the way learning takes place.

8 May 2025

Vaccines of the Future: Harnessing the Immune System for Long-Lasting Protection

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies.

8 May 2025

Memories of Cold Experiences Influence Metabolism and Thermoregulation

A groundbreaking study reveals that recalling cold experiences can activate thermoregulation and metabolism in mice, suggesting memory-based interventions could help treat obesity, diabetes, and temperature-related disorders like Raynaud’s disease.

6 May 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

The Entropy of DNA Methylation States can Estimate Chronological Age

Recent findings link DNA methylation entropy to chronological age, offering insights into epigenetic changes that could inform age-related disease treatments.

24 Apr 2025

Birds Hold Remarkable Clues to Fighting Human and Animal Infections

Australian and Dutch researchers have uncovered a remarkable evolutionary adaptation in birds that could hold vital clues for combating avian flu and respiratory infections in humans, including pneumonia and COVID-19.

24 Apr 2025

New Blood Test Could Revolutionize Alzheimer’s Diagnosis

Research confirms the Lumipulse serum p-tau217 assay's effectiveness in diagnosing Alzheimer's, paving the way for accessible blood-based testing in healthcare.

18 Apr 2025

Rapid Growth of Blood Cancer Driven by a Single Genetic ‘HIT’

A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

10 Apr 2025

Spinning Into Resistance: The Flagella’s Hidden Role

A new study from the Hebrew University of Jerusalem reveals that bacterial movement plays a central role in the transfer of antibiotic resistance genes. The research team discovered that the rotation of flagella in Bacillus subtilis acts as a mechanical signal that activates key conjugation genes.

8 Apr 2025

Meet Lariocidin: A Game-Changing Antibiotic That Outsmarts Resistance

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant bacterial infections effectively.

4 Apr 2025