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Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

Regenerative Vascular Grafts Solve Key Shortage In Surgery

Engineered biotubes demonstrate strong mechanical performance and rapid tissue regeneration, offering a scalable solution to the vascular graft shortage.

2 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

PAX3 Protein Plays Key Roles in Development and Cancer

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression.

19 Mar 2026

Psoriasis-Like Inflammation Limits Skin Cancer Growth

A study shows that psoriasis-like immune responses may limit skin cancer growth, challenging the view of chronic inflammation as solely tumor-promoting.

19 Mar 2026

Certain Antibiotics Leave Lasting Footprints on Human Gut Microbiome

Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time.

13 Mar 2026

Novel INSTALL Technology Achieves Non-Toxic Gene Integration in Multiple Cell Types

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

12 Mar 2026

Study Reveals Microbiome Role in Protecting the Colon From Tissue Injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

11 Mar 2026

Setd8 Enzyme Preserves Retinal Progenitor Identity During Eye Development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

10 Mar 2026

Genetically Engineered Stem Cells Successfully Overcome Immune Rejection in Mice

A study published today in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model.

6 Mar 2026

Blood Tau217 Test Predicts When Alzheimer’s Symptoms May Begin

The %p-tau217 biomarker in blood offers a novel approach to estimate Alzheimer's onset, potentially transforming prevention trial strategies.

5 Mar 2026

Select Small Non-Coding RNAs May Predict Survival in Older Adults

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a person lives.

26 Feb 2026

Large-Scale Study Maps DNA Variants Shaping Human Disease Risk

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits.

26 Feb 2026

Study Reveals Cellular Blueprint of the Human Liver

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians capture the spatial microstructure of multiple lobes of this multitasking organ.

24 Feb 2026