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New Cannabinoid Drug Brings Hope For Treating Chronic Pain Without Addiction

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

13 Mar 2025

‘Rescue’ Mutations Protect Liver From Damage in Patients With Genetic Disorder

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency, new research shows.

11 Mar 2025

Protective ‘Slime’ In The Brain May Help Prevent Aging And Neurodegeneration

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, paving the way for new treatments.

10 Mar 2025

Pain and Itch Processed by Distinct Neurons in the Anterior Cingulate Cortex

A research team led by KAANG Bong-Kiun, director of the Center for Cognition and Sociality within the Institute for Basic Science (IBS), and KO Hyoung-Gon, professor at Kyung Hee University College of Dentistry, have uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC).

5 Mar 2025

Arab Pangenome Reference Provides New Path for Advancing Precision Medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

5 Mar 2025

Lactylation Levels Influence Cardiac Development and Regeneration in Mice

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

3 Mar 2025

New Cancer-on-Chip Tech Could Replace Animal Testing—Faster, Cheaper, More Accurate!

A new modified silicone rubber for cancer-on-chip applications improves cell adhesion and drug testing, paving the way for personalized cancer treatments.

28 Feb 2025

RNA Splicing Errors May Hold the Key to Beating Gliomas Using Immunotherapy

Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for this challenging brain tumor.

26 Feb 2025

Unlocking Cancer’s Secret Strategy: Tumor Cells Work Together To Survive

Research uncovers tumor cell cooperation via CNDP2, suggesting new therapeutic strategies that disrupt nutrient sharing to inhibit cancer growth effectively.

25 Feb 2025

New Visualization Technique Reveals Geometric Patterns in Brain Activity

Researchers at University of Tsukuba have applied a visualization technique to depict the brain's activity related to visual perception as geometric patterns.

24 Feb 2025

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

Study Reveals How the Brain Gauges Risk and Reward in Decision-Making

Every day, our brain makes thousands of decisions, big and small. Any of these decisions - from the least consequential such as picking a restaurant to the more important such as pursuing a different career or moving to a new city - may result in better or worse outcomes.

20 Feb 2025