Molecular & Structural Biology

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Researchers develop new AI model to bridge biology and chemistry

Insilico Medicine announces the publication of a new research paper titled "Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders" in Frontiers in Pharmacology.

20 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020

Scientists develop computer model to accurately predict brain age

Scientists have trained a computer to analyze different types of brain scan and predict the age of the human brain, according to a new study in the open-access journal eLife.

20 May 2020

Protein modification may cause long-term consequences

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

20 May 2020

Rib movements evolved during locomotion, then co-opted for breathing

When early tetrapods transitioned from water to land the way they breathed air underwent an evolutionary revolution.

20 May 2020

MicroRNAs play a key role in regulating the function of immune cells

According to a recent study, the ability of the immune system to mobilize specialized cells to fight against infections depends partly on small molecules.

19 May 2020

Gene mutation regulates plant responses to biotic stress

At times, scientists initiate their studies and find exactly what they had been looking for, while sometimes they end up with something unanticipated.

19 May 2020

Scientists develop a new way to reactivate silenced genes

All cells in an organism are known to have the same genetic data but not all carry out the same function. This is because all the cells do not contain the same active genes.

19 May 2020

Researchers develop a reliable technique for assessing the role of lncRNAs

The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects.

18 May 2020

New blood test may help track individual fat intake

McMaster University researchers have developed a precise and reliable blood test to monitor the intake of fats by individuals. This blood test may serve as a tool to guide public health policy related to healthy eating.

18 May 2020

The brain suppresses outside information during dreaming phase

Scientists from the CNRS and the ENS-PSL in France and Monash University in Australia have shown that the brain suppresses information from the outside world, such as the sound of a conversation, during the sleep phase linked to dreaming.

18 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Novel method sheds light on genomes of bacteria and viruses

According to a new study, biologists from the University of Alberta have developed a unique method for sequencing circular DNA.

18 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Research reveals community structure of microorganisms living around Antarctic lakes

A research group of Assistant Prof. Yuu Hirose of the Department of Applied Chemistry and Life Science at Toyohashi University of Technology, Niigata University, the Japan Agency for Marine-Earth Science and Technology, and the National Institute of Polar Research, has revealed the community structure of microorganisms living around freshwater lakes in the Langhovde and Skarvsnes ice-free areas of Antarctica.

15 May 2020

Researchers discover group of genes with altered expression in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end.

15 May 2020

Coronavirus attacking microRNA numbers reduce with age

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

14 May 2020