Molecular & Structural Biology

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PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage response.

26 Oct 2026

Taurine Deficiency Triggers Innate Immune Sensing of Cellular Danger Signals

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

26 Oct 2026

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Precision-cut lung slices allow researchers to study living human lung tissue outside the body, preserving the different cell types and structures that make up the organ.

24 Oct 2026

Tower Sensing and Genetics Reveal Time-Shifting Phenotypes in Cottonwood Canopies

Black cottonwood is a fast-growing, genetically diverse tree with potential as a lignocellulosic feedstock for biofuels, including sustainable aviation fuels.

24 Oct 2026

Scientists Discover Molecular Cascade Behind Brain Dysregulation in Angelman Syndrome

Angelman syndrome is a rare disease with a single known cause: one missing gene. The lack of that gene, normally inherited from the mother, occurs in approximately one in 20,000 births and is associated with cognitive and mobility deficits that become evident in children when they are around 6 months of age.

24 Oct 2026

Genetic Clue to Autism's Fourfold Difference In Boys and Girls

Findings on MECP2 regulatory variants suggest genetic factors contribute to autism's male bias, enhancing understanding of the disorder's heritability.

22 Oct 2026

Accelerating RNA Therapeutics Research with High Throughput Screening

Oligonucleotides have the potential to transform the treatment of a wide range of diseases, and have extensive applications in biomedical research.

From INTEGRA Biosciences 22 Oct 2026

INmune Bio Establishes Global Commercialization Framework for Ebstrocel™ Through Strategic Agreement with Uniphar

INmune Bio Inc. (the “Company”), a late-stage biotechnology company focused on inflammation and immunology, today announced that it has entered into a Master Services Agreement with Uniphar Durbin Ireland Limited (“Uniphar”) establishing a scalable framework to support international access, distribution and commercialization of Ebstrocel™, the Company’s allogeneic stromal cell therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB).

From INmune Bio 22 Oct 2026

Collective Cell Migration Establishes Tissue Scale Planar Cell Polarity

From the hairs on our arms to the microscopic sensory structures of the inner ear, many tissues in the body are built with a clear sense of direction.

20 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Live Organelle Imaging Catches Early Neuronal Stress Before Cell Death

Scientists studying amyotrophic lateral sclerosis (ALS), Parkinson's, Alzheimer's and other neurological diseases are getting unprecedented views inside brain cells, using powerful new microscopes to uncover changes that may begin long before neurons die.

20 Oct 2026

Study Details Mechanisms Driving Irreversible Fungal Cell Wall Fusion

The fusion of two cells is a decisive event in the sexual reproduction of many organisms. In fungi, cells must not only bring their membranes together and merge them, but also locally open their protective cell wall.

20 Oct 2026

Could mRNA Vaccine Technology Help Repair Damaged Livers?

Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery.

16 Oct 2026

Immature Viral Procapsids Facilitate Evolutionary Shifts Toward Cellular Protein Compartments

Researchers at the University of Miami have identified a group of previously unknown viruses that bridge an evolutionary gap between viruses and cellular protein compartments, a discovery with important implications for both biotechnology and scientists’ understanding of the origins of life.

16 Oct 2026

Naturally Occurring Protein Balances Immune Protection and Excessive Tissue Inflammation

A naturally occurring protein can help the immune system fight viral infections while also reducing the damaging inflammation that often accompanies them, a new study from McMaster University has found.

16 Oct 2026

Targeted Interneuron Manipulation Improves Learning and Memory Processing Capabilities

Researchers were able to restore the function of neurons linked to cognitive function and information processing in mice that mimic key features of Alzheimer's disease, showing early promise for the development of a similar targeted therapy in humans.

16 Oct 2026

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

The stability of the human gut microbiome relies on interactions between different bacterial species. However, the specific molecular mechanisms of these interactions, particularly among non-dominant species, remain largely unexplored.

16 Oct 2026

Immunometabolic Reprogramming Strategy Addresses Chronic Inflammatory Conditions

Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.

16 Oct 2026

Mount Sinai Launches Bioengineered Brain and Heart Models Into Space

Mount Sinai researchers are sending bioengineered human brain and cardiovascular tissue models into space for the first time today, as part of the SpaceX CRS-35 mission, to study brain activity, cardiovascular function, and accelerated aging in orbit.

15 Oct 2026

Cryo-EM Snapshots Capture Multi-Stage Structural Transitions During DNA Recombination

Bacteriophages, or viruses that infect bacteria, have a fiendishly simple purpose in life: attach to a bacterial cell, inject their DNA, and then use the host's genetic machinery to reproduce. In doing so, they may have evolved some of the most efficient gene editing tools ever seen in nature.

15 Oct 2026

Molecular & Structural Biology

PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

Taurine Deficiency Triggers Innate Immune Sensing of Cellular Danger Signals

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Tower Sensing and Genetics Reveal Time-Shifting Phenotypes in Cottonwood Canopies

Scientists Discover Molecular Cascade Behind Brain Dysregulation in Angelman Syndrome

Genetic Clue to Autism's Fourfold Difference In Boys and Girls

Accelerating RNA Therapeutics Research with High Throughput Screening

INmune Bio Establishes Global Commercialization Framework for Ebstrocel™ Through Strategic Agreement with Uniphar

Collective Cell Migration Establishes Tissue Scale Planar Cell Polarity

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Live Organelle Imaging Catches Early Neuronal Stress Before Cell Death

Study Details Mechanisms Driving Irreversible Fungal Cell Wall Fusion

Could mRNA Vaccine Technology Help Repair Damaged Livers?

Immature Viral Procapsids Facilitate Evolutionary Shifts Toward Cellular Protein Compartments

Naturally Occurring Protein Balances Immune Protection and Excessive Tissue Inflammation

Targeted Interneuron Manipulation Improves Learning and Memory Processing Capabilities

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

Immunometabolic Reprogramming Strategy Addresses Chronic Inflammatory Conditions

Mount Sinai Launches Bioengineered Brain and Heart Models Into Space

Cryo-EM Snapshots Capture Multi-Stage Structural Transitions During DNA Recombination

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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