Molecular & Structural Biology

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Unraveling the “Dark Energy” Found in the Structural Protein Universe

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but necessary to explain cosmology.

28 Jan 2026

Rice Researchers Create Accurate 3D Structures of Chromosomes Using FI-Chrom Method

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't used as often.

28 Jan 2026

Novel Epigenetic Regulator Enhances Downy Mildew Resistance in Brassica rapa

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when plants are highly vulnerable to infection.

27 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

Bioinformatic Framework Reconstructs Evolutionary History of Complex Polyploid Genomes

Whole-genome duplication has repeatedly reshaped plant genomes and driven evolutionary innovation, ecological adaptation, and crop diversification.

24 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

First Fully Synthetic Bacteriophage Engineering System for Antibiotic-Resistant Bacterium

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century.

21 Jan 2026

Rigid Protein Molecular Rulers Enable Precise Control of Antibody Conformation

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein-based "molecular rulers" that could probe antibody shape, limit unwanted motion, and support safer, more effective antibody drug design.

21 Jan 2026

Decoding the Molecular Logic of Histamine Signaling in the Brain

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses.

19 Jan 2026

Study Overturns Understanding About How T Cells Recognize Lipid Antigens

A new discovery about how cells communicate with each other in the body's immune system has revealed deeper insights for an international team of scientists into fundamental immune system function.

16 Jan 2026

Unveiling How a Respiratory Bacterium Obtains Lipids and Targets Fatty Tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

Backyard Soil Bacterium Produces Antibiotic Built to Outsmart Resistance

Early in 2025, scientists discovered a promising new antibiotic in a soil sample from a lab technician's backyard.

16 Jan 2026

Scientists Identify TRPM4 as Key Molecular Switch Controlling Intestinal Fluid Balance

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

12 Jan 2026

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining translational features critical for proper protein folding.

9 Jan 2026

Specialized Immune Cells Grown in Labs Offer Hope for Autoimmune Patients

Researchers at the University of British Columbia (UBC) have made a significant discovery regarding the cultivation of specialized immune cells, facilitating the development of readily available off-the-shelf cell therapies aimed at treating cancer, autoimmune diseases, and additional conditions.

9 Jan 2026

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

8 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Molecular & Structural Biology

Unraveling the “Dark Energy” Found in the Structural Protein Universe

Rice Researchers Create Accurate 3D Structures of Chromosomes Using FI-Chrom Method

Novel Epigenetic Regulator Enhances Downy Mildew Resistance in Brassica rapa

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

Bioinformatic Framework Reconstructs Evolutionary History of Complex Polyploid Genomes

Coordinated Gene Regulation Drives Saponin Production

First Fully Synthetic Bacteriophage Engineering System for Antibiotic-Resistant Bacterium

Rigid Protein Molecular Rulers Enable Precise Control of Antibody Conformation

Decoding the Molecular Logic of Histamine Signaling in the Brain

Study Overturns Understanding About How T Cells Recognize Lipid Antigens

Unveiling How a Respiratory Bacterium Obtains Lipids and Targets Fatty Tissues

Backyard Soil Bacterium Produces Antibiotic Built to Outsmart Resistance

Scientists Identify TRPM4 as Key Molecular Switch Controlling Intestinal Fluid Balance

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

Specialized Immune Cells Grown in Labs Offer Hope for Autoimmune Patients

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Identifying Molecules That Activate and Inhibit Key Protein Function

Dual Genetic Mutations Drive RNA Mis-Splicing and Leukemia Progression

Hidden Molecular "Control Switch" Uncovered Inside TRPM5 Protein

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Latest in Genomics