Molecular & Structural Biology

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New Proximity Labeling Method Discovers Critical Protein Interactions in Cancer

Using a photochemically driven labeling technique, a Cornell University-led research group has devised a strategy for capturing cancer-specific protein-to-protein interactions, which could one day spawn targeted therapies for prostate, small-cell lung, pancreatic and other deadly forms of the disease.

14 Aug 2026

Researchers Uncover Hidden Switch Helping Cancer Evade Immune Systems

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's immune system.

14 Aug 2026

New Mouse Study Challenges Traditional Theories of Long-Term Memory Storage

Memories can survive even after the brain temporarily loses more than half of its synaptic connections, according to a new mouse study, which challenges the long-held view that long-term memories depend on stable individual synapses.

14 Aug 2026

Bacterial Membrane Particles Emerge As Promising Tools in Oncology Research

Bacteria shed membrane-enclosed tiny particles filled with proteins, lipids, DNA, RNA and metabolites. These particles, commonly known as bacterial extracellular vesicles (BEVs), are now being explored as possible tools for cancer diagnosis and treatment.

14 Aug 2026

ORBIT Technology Leverages DNA Origami for Next-Generation Biological Discovery

Scientists often describe life as a series of chemical reactions. Pallav Kosuri, PhD, describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells, and bodies-without movement, there is no life.

14 Aug 2026

Novel Approach Provides a Flexible Foundation for Measuring Coronavirus Protease Activity

A research team has computationally designed a synthetic peptide that enables modular detection of the enzymatic activity of coronavirus 3C-like protease (3CLPro), an enzyme essential for viral replication and maturation.

13 Aug 2026

Study Reveals Previously Unknown Mechanism of RNA Synthesis Shared Across Life Forms

Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP).

13 Aug 2026

High Resolution Imaging Exposes Root Causes of Chronic Heart Rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

13 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

Transition From Milk to Solid Food Shapes Immune System Development

The early period of life is a critical phase in which the immune system must learn to tolerate harmless environmental stimuli, such as food and microbes that normally live in and on the body, while remaining vigilant against harmful substances and pathogens.

12 Aug 2026

Scientists Map Overlapping Fluorescent Proteins Using Advanced Lifetime Microscopy Techniques

Fluorescent protein imaging is an indispensable tool in life science research, enabling visualization of protein movement and localization, gene expression, signaling pathways, protein-protein interactions, and more.

12 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

New Single-Cell Database Reveals Hidden Inner Workings of Spinal Cord Circuits

Scientists at St. Jude Children's Research Hospital created a single-cell atlas of a key class of spinal neurons involved in motor coordination. From that resource, they identified a small subgroup of interneurons associated with the speed of rhythmic movements such as walking. The findings, which have implications for understanding spinal cord function and recovery from injury, were published today in Nature Communications.

11 Aug 2026

Rare Immune Cell Spatial DNA Maps Uncover Hidden Autoimmune Triggers

A new study co-led by Prof. Valeriya Malysheva, group leader at the VIB-UAntwerp Center for Molecular Neurology, has been published in Nature Genetics.

8 Aug 2026

Brain Executive Control Centers Block Creative Problem Solving in Mice

The prefrontal cortex, a brain region long associated with learning more flexible behaviors, can sometimes block the ability to think outside the box, a new study in mice shows. Science Advances published the finding by biologists at Emory University.

8 Aug 2026

Decoding Brown Rat Pangenomes Provides Accurate Blueprints for Human Illness

Researchers have created the most complete genetic profile of the brown rat to date, according to a UTHealth Houston-led team, paving the way for scientists to more accurately research the genetic links to conditions like heart disease, kidney disease, high blood pressure, and stroke.

8 Aug 2026