Molecular & Structural Biology

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Identifying a Genetic Switch That Halts Human Nerve Regeneration

Researchers at Cambridge have created tiny circuits in the lab that replicate the connections between the brain and spinal cord, which control human movements.

29 May 2026

New Molecular Map Traces Human Disease Genes Back to LECA

A University of Texas at Austin-led team has reconstructed the most detailed map to date of the molecular machines that carried out the functions of life in an ancient ancestor that gave rise to all complex life on Earth, including us, shedding new light on genetic causes of human diseases.

28 May 2026

Cells Sense Abnormal RNA Patterns to Silence Jumping Genes

Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell survival if left unchecked. Cells control these "jumping genes" by silencing them, but little was known about how cells recognize and defend themselves from invading transposons.

27 May 2026

Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant Tumors

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

26 May 2026

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Aggressive Breast Cancer Cells Lose Spatial Persistence When Exposed to Wireless Electric Fields

Traditional electrotaxis assays place electrodes directly into the cell culture medium, which inevitably drives current through the sample.

26 May 2026

Dividing Cells Replicate Chromosomal Errors to Trigger Advanced Tumor Progression and Growth

Megan Sweet slices tumors.

26 May 2026

Scientists Reconstruct a 700-Million-Year Evolutionary Tree of Blood Cells

Almost all animal species -- including humans -- have blood cells, but between different species our blood tells different stories. The lineage and components of blood cells vary widely, and this variety is a testament to how animals have evolved to protect themselves from infectious diseases.

26 May 2026

Advanced Framework Improves Gene Set Enrichment Analysis to Uncover Hidden Multi-Omics Data Insights

Scientists at the Icahn School of Medicine at Mount Sinai have created a new artificial intelligence (AI) model that helps reveal how genes function together inside human cells, offering a powerful new way to understand biology and disease.

25 May 2026

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.

25 May 2026

Inflammatory Cytokines Trigger Higher Protein Levels as a Natural Defense Mechanism Against Disease

A new study from researchers at the University of Chicago provides important insight into how the pancreas protects itself during inflammation, pointing to promising new directions for treating pancreatitis.

23 May 2026

Specialized Intative Cells Release Peptide Hormones to Rapidly Signal an Amino Acid Deficiency

Eating is not only about getting enough calories. Animals also need to choose the right nutrients. When the body lacks protein, it must seek essential amino acids - the protein building blocks that cannot be made internally and must come from food.

23 May 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

Study Explains Why Persistent Gut Damage Continues Despite HIV Treatments

For many people living with HIV, today's treatments can suppress the virus and dramatically improve health. But even when HIV is controlled, damage to the gut caused by the disease can persist, fueling chronic inflammation linked to serious health problems. A new Tulane University study published in JCI Insight helps explains why.

23 May 2026

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods-and these organoids grow their own nerve cells.

23 May 2026

Researchers Use Yeast Sugar Molecules to Extend COVID Vaccine Immunity in Mice

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years. The combo also showed a more pronounced response against omicron viral components than the vaccine alone.

23 May 2026

AI Designs Custom Miniproteins to Precisely Control Cell Receptors

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies - from the ability to see and smell, to sensing of adrenaline, insulin, nutrients and medicines.

22 May 2026

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

22 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss. Teeth have an intrinsic capability to regenerate, a process which is driven by dental pulp stem cells (DPSCs) which replenish the dental pulp including the dentin-producing cells called odontoblasts.

22 May 2026

Molecular & Structural Biology

Identifying a Genetic Switch That Halts Human Nerve Regeneration

New Molecular Map Traces Human Disease Genes Back to LECA

Cells Sense Abnormal RNA Patterns to Silence Jumping Genes

Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant Tumors

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

Aggressive Breast Cancer Cells Lose Spatial Persistence When Exposed to Wireless Electric Fields

Dividing Cells Replicate Chromosomal Errors to Trigger Advanced Tumor Progression and Growth

Scientists Reconstruct a 700-Million-Year Evolutionary Tree of Blood Cells

Advanced Framework Improves Gene Set Enrichment Analysis to Uncover Hidden Multi-Omics Data Insights

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

Inflammatory Cytokines Trigger Higher Protein Levels as a Natural Defense Mechanism Against Disease

Specialized Intative Cells Release Peptide Hormones to Rapidly Signal an Amino Acid Deficiency

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

Study Explains Why Persistent Gut Damage Continues Despite HIV Treatments

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Researchers Use Yeast Sugar Molecules to Extend COVID Vaccine Immunity in Mice

AI Designs Custom Miniproteins to Precisely Control Cell Receptors

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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