Molecular & Structural Biology

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Rare Immune Cell Spatial DNA Maps Uncover Hidden Autoimmune Triggers

Rare Immune Cell Spatial DNA Maps Uncover Hidden Autoimmune Triggers

A new study co-led by Prof. Valeriya Malysheva, group leader at the VIB-UAntwerp Center for Molecular Neurology, has been published in Nature Genetics.

8 Aug 2026

Brain Executive Control Centers Block Creative Problem Solving in Mice

Brain Executive Control Centers Block Creative Problem Solving in Mice

The prefrontal cortex, a brain region long associated with learning more flexible behaviors, can sometimes block the ability to think outside the box, a new study in mice shows. Science Advances published the finding by biologists at Emory University.

8 Aug 2026

Decoding Brown Rat Pangenomes Provides Accurate Blueprints for Human Illness

Decoding Brown Rat Pangenomes Provides Accurate Blueprints for Human Illness

Researchers have created the most complete genetic profile of the brown rat to date, according to a UTHealth Houston-led team, paving the way for scientists to more accurately research the genetic links to conditions like heart disease, kidney disease, high blood pressure, and stroke.

8 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Scientists Track Specialized Small RNAs Governing Safe Stem Cell Development

Scientists Track Specialized Small RNAs Governing Safe Stem Cell Development

Scientists are shedding new light on a little-known biological system that could help unlock the full potential of stem cell therapy, one of the most promising areas of modern medicine.

7 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Living Organisms Depend on Bacterial Production of Critical Vitamin B12

Living Organisms Depend on Bacterial Production of Critical Vitamin B12

All living organisms need a little bit of it to form red blood cells and DNA, as well as to build and support brain and nerve cells. But it's hard to come by: Humans don't make it. Animals don't make it. Plants don't make it.

7 Aug 2026

Modulating T Cell Exhaustion Offers Novel Therapeutic Pathways in Transplantation

Modulating T Cell Exhaustion Offers Novel Therapeutic Pathways in Transplantation

A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this dysfunctional immune state can both promote graft tolerance and create vulnerabilities to infection and malignancy.

7 Aug 2026

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

A new review highlights the growing importance of circular RNAs (circRNAs) in addressing one of the most pressing challenges in modern oncology: treatment-related toxicity.

6 Aug 2026

Blood Immune Cells Cross Protective Barriers to Transform Aging Brains

Blood Immune Cells Cross Protective Barriers to Transform Aging Brains

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Cells can switch off genes by tightly packaging DNA around proteins called histones.

6 Aug 2026

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Researchers at Mayo Clinic have identified a protein that cancer cells use to suppress the body's immune response, a finding that could support the development of new treatments to improve the effectiveness of cancer immunotherapies.

5 Aug 2026

Mapping Spatial Genome Architecture Unlocks Hidden Biological Mechanisms Behind Genetic Risk

Mapping Spatial Genome Architecture Unlocks Hidden Biological Mechanisms Behind Genetic Risk

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA sequence.

5 Aug 2026

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

New Analytical Framework Captures Coordinated Host and Microbial Disease Responses

New Analytical Framework Captures Coordinated Host and Microbial Disease Responses

The trillions of microorganisms living in our intestine influence our health, from digestion and metabolism to immunity.

5 Aug 2026

Genetic and Environmental Factors Shape Crucial Cell Fitness Level Variations

Genetic and Environmental Factors Shape Crucial Cell Fitness Level Variations

How readily a cell divides and how well it survives is fundamental to life, shaping everything from organ size to the body’s ability to withstand disease.

5 Aug 2026

Researchers Track Genetic Mutation Clues Behind Accelerated Aging Vascular Decline

Researchers Track Genetic Mutation Clues Behind Accelerated Aging Vascular Decline

Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature ageing. Most patients die during their teenage years from cardiovascular disease, but the precise mechanisms underlying vascular damage remain unclear.

5 Aug 2026

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases.

3 Aug 2026

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Salt stress is one of the most destructive environmental threats to crop production, causing osmotic imbalance, ion toxicity, and oxidative damage that stunt growth and reduce yields.

3 Aug 2026

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