Molecular & Structural Biology

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Study Maps the Complete Genetic Blueprint for Loganin Biosynthesis

Plant-derived terpenoids play essential roles in medicine, agriculture, and human health, but their biosynthesis is often complex and tightly regulated.

5 Mar 2026

Study Demonstrates Information Exchange Between Right-Handed and Mirror DNA

A new study by NYU chemists finds that DNA tiles can assemble into 3D structures without the sticky cohesion of hydrogen bonding. This finding, published in Nature Communications, turns a fundamental paradigm in the field of DNA self-assembly on its head.

3 Mar 2026

How Catalytic RNA Redefined Enzymes and the Origin of Life

There have been many important discoveries along the path to what we know today about RNA, or ribonucleic acid-a molecule found in every living cell that helps carry and interpret genetic instructions.

2 Mar 2026

Promega Unveils Cellular Target Engagement Technology Aimed at Expanding the Druggable Proteome at SLAS 2026

Promega Corporation is launching a new live-cell target engagement platform that could close a long-standing gap between biochemical and cellular assays for understudied or difficult-to-interrogate proteins.

27 Feb 2026

Structural Blueprint of Cellular Biomolecular Condensates Opens New Therapeutic Possibilities

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

26 Feb 2026

Scientists Discover Unique Chromosome Reorganization in Developing Germ Cells

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic precursors of these cells uniquely reshape the 3D organization of their genetic material.

23 Feb 2026

Brain Enzymes MNK1 and MNK2 Regulate Distinct Behaviors in the Brain

Researchers at the Max Delbrück Center show that two related enzymes, MNK1 and MNK2, act on the brain to regulate different behaviors.

20 Feb 2026

Scientists Map Protein Production Across Individual Brain Cells

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

19 Feb 2026

Study Reveals New Structural Role for HIV Integrase

The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.

19 Feb 2026

Chemical Tweaks Boost Peptide Stability and Antimicrobial Power

Antibiotic treatments are losing effectiveness against a range of common bacterial pathogens, including E. coli, K. pneumoniae, Salmonella and Acinetobacter, according to a warning issued by the World Health Organization last October.

16 Feb 2026

Protrusion-Derived EVs Boost Protein Delivery Efficiency

Extracellular vesicles (EVs) are tiny membrane-bound particles released by cells to transport proteins and other molecules to neighboring cells. Because of this natural delivery ability, EVs have attracted growing interest as potential vehicles for therapeutic protein and genome-editing enzyme delivery.

16 Feb 2026

Mapping the Binding Energy of Histamine Receptors

G-protein-coupled receptors (GPCRs) are one of the biggest groups of cell surface proteins in the human body, recognizing hormones, neurotransmitters, and drugs.

16 Feb 2026

Complete Flax Genome Assembly Advances Fatty Acid Research

Flax (Linum usitatissimum L.) is one of the richest plant sources of alpha-linolenic acid, an essential omega-3 fatty acid linked to human health benefits ranging from cardiovascular protection to metabolic regulation.

13 Feb 2026

The Genetic Mechanics of Bacterial Circadian Clocks

Circadian clocks play an important role in our health and well-being by synchronizing the 24-hour biological cycles with light and dark exposure. Disruptions in the rhythms of these clocks, such as jet lag and daylight saving time, might put their everyday operations out of sync.

11 Feb 2026

Cells Use Protein Partnership to Manage Oxidative Stress

Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance.

10 Feb 2026

Microglia Found to Drive New Neuron Growth in Adult Hippocampus

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

10 Feb 2026

Powerful New Enzyme Efficiently Synthesizes RNA

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine.

10 Feb 2026

New Gene-Editing Strategy to Eliminate Aggressive Cancer Cells

The initiation and severity of cancer are associated with the atypical behavior of specific genes, referred to as oncogenes. The most recognized of these changes is mutation; however, it is not the sole alteration.

9 Feb 2026

Disordered Mitochondrial Protein Guides Electron Traffic for Metabolism

For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery of mitochondria - the organelles that crank out adenosine triphosphate (ATP), the universal "energy currency" of cells - one of the most enigmatic components is a protein that appears anything but orderly.

6 Feb 2026

New Insights into TRiC and Prefoldin Mechanics

Proteins are the molecular machines of cells. They are manufactured in protein factories known as ribosomes using their blueprint, or genetic information.

6 Feb 2026