Molecular & Structural Biology

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Changes in RNA Regulation Enable Bacteria to Enter Antibiotic Tolerance

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics. St. Jude Children's Research Hospital scientists have uncovered how S. pneumoniae adapts to antibiotic exposure and immune pressures.

23 Jul 2026

Artificially Recreating C3 Effects Overcomes Resistance in Hard-to-Treat Tumors

An ancient molecule that existed long before the blood circulation system evolved, has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to prevent the accumulation of immunosuppressive cells, but only when produced inside the tumor.

23 Jul 2026

Study Identifies a Brain Pathway That Drives Maternal Reward and Bonding

New research has found a hormone is responsible for making mothers' interactions with newborns feel rewarding rather than just necessary.

23 Jul 2026

New Open Source AI Toolkit Identifies Promising Peptide Medicines

Penn Engineers have developed PeptiVerse, an AI-powered platform that predicts key chemical and biological properties of peptides, the strings of amino acids whose medical potential has been demonstrated by the success of GLP-1 drugs, the widely used weight-loss treatments.

22 Jul 2026

Engineered Mice Carrying the Genetic Variant Develop Excessive Sweating

Johns Hopkins Medicine researchers have identified a genetic driver of primary idiopathic hyperhidrosis, a chronic condition that causes excessive sweating, providing some of the strongest evidence to date that the disorder can originate in the nervous system and may be treatable with targeted therapies.

22 Jul 2026

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Hidden Cellular Sub Compartments Drive Final Steps of Ribosome Assembly

The nucleolus is a liquid-like cellular organelle where protein factories called ribosomes are assembled.

20 Jul 2026

AI Breakthrough Generates Novel Synthetic RNA-Guided Nucleases

Artificial intelligence (AI)-designed proteins can now expand the CRISPR toolbox beyond what evolution has produced.

17 Jul 2026

Individual Brain Cells Store Long-Term Memories Utilizing Independent Dendrites

Branchlike structures called dendrites that extend from neurons appear to make their own computations independent of the cell body, helping individual brain cells store memories of the past, respond to the present, and anticipate the future, a study led by UT Southwestern Medical Center researchers suggests.

17 Jul 2026

Advanced Cellular Mapping Preserves Spatial Architecture During Holistic Herb Interventions

Traditional Chinese medicine is widely recognized for its holistic and systematic mode of action, often described as "multi-component, multi-target, and multi-pathway" regulation.

17 Jul 2026

New Chicken Immune Pathway Bypasses Vital Bursa of Fabricius

Birds possess a specialized organ called the bursa of Fabricius which mammals do not have.

17 Jul 2026

Dynamic Multi Tasking Neurons Help Brains Solve Varied Daily Tasks

What scientific findings proved so compelling that more than 11,000 preliminary copies of them have been downloaded before they finally appeared in today's Nature?

16 Jul 2026

Researchers Discover Surprising Protective Microglia Roles in Dementia

Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain – play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease.

16 Jul 2026

Short Peptide Molecular Tool Targets Key Diagnostic Disease-Related Proteins

Proteins regulate a wide range of biological processes inside and outside cells by binding to specific molecular partners.

16 Jul 2026

New Biological Targets Aim to Halt Idiopathic Pulmonary Fibrosis

Pulmonary fibrosis is a deadly disease where scar tissue grows in the lungs, making breathing more difficult.

16 Jul 2026

MIT Researchers Grow Blood Vessels by Stretching Them

Tissue engineers are developing methods to produce living organs and tissues from cells in order to replace diseased and damaged ones in the body.

15 Jul 2026

Arc Protein Identified as Driving Tau Spread in Alzheimer's Disease

Arc's involvement in tau transmission via extracellular vesicles offers new understanding of Alzheimer's disease mechanisms and potential therapeutic pathways.

15 Jul 2026

Breakthrough Imaging Method Maps Whole Cell Signals

Cells are crowded, dynamic places where thousands of molecules interact in tight quarters. Until now, scientists lacked a reliable way to see many of these molecular interactions as they happen.

15 Jul 2026

Enigmatic MLL4 Protein Drives Leukemia While Suppressing Solid Tumors

The epigenetic modifier MLL4 has an unassuming name-the 4, for instance, indicates it's just one in a family of such modifiers.

14 Jul 2026

New Double Donut Structure Reveals How SPOP Protein Regulates Cancer

Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the presence and absence of these mutations.

14 Jul 2026