Molecular & Structural Biology

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Label-Free Raman Spectroscopy Accelerates Precision Phage Therapy

This study was led by Prof. Jian Xu (Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences) in collaboration with Prof. Hongzhou Lu (Shenzhen Third People's Hospital) and Prof. Jiadong Huang (University of Jinan).

8 Jun 2026

Deep Mutational Scanning Unlocks Hidden Blueprint of Antibody Selection Processes

A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently produces highly effective antibodies.

8 Jun 2026

New Method Dissects Light Signaling and Heme Pathways in Chloroplast Formation

For plants, light is an important environmental factor not only as a source of energy for photosynthesis but also as a signal for capturing environmental information. Light signals are sensed by photoreceptor proteins called phytochrome. The amino acids that make up proteins are transparent and cannot absorb visible light.

8 Jun 2026

Study Shows Environmental Mixing Drives Primitive RNA to Extinction

Recent research showed that an artificially constructed RNA self-replicating system modeling primitive life at the origin of life evolved to become more prone to extinction under certain experimental conditions.

8 Jun 2026

New Study Proves Research Models Accurately Replicate Cancer ecDNA Loops

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from a glacier. Just as icebergs are a threat to ships and their crew, these scattered bits of DNA loom large to physicians and cancer patients by having titanic effects on tumor progression and treatment resistance.

8 Jun 2026

Biologists Capture Snapshot of Evolutionary Transition in Y Chromosome Gene

The study, published in Volume 153, Issue 9 of the journal Development on May 14, 2026, by The Company of Biologists, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early human development.

8 Jun 2026

Antibody-Directed Xenophagy Pathway Blocks Intracellular Infections From Spreading

Scientists have revealed the process by which cells can internally digest bacteria and viruses.

5 Jun 2026

Scientists Identify Microglia Immune State Changes for Novel Alzheimer’s Therapies

Researchers from VIB, KU Leuven, the UK-DRI and Muna Therapeutics, funded by, among others, ERC, have uncovered a critical biological transition that may determine whether Alzheimer's disease pathology leads to dementia.

5 Jun 2026

New Antibiotic Compound Blocks Ribosome to Starve Dangerous Pathogens

Researchers at McMaster University have discovered a new antibiotic that kills some of the world's most dangerous and drug-resistant bacteria - and does so by targeting a previously unknown vulnerability, opening the door to an entirely new class of treatments.

5 Jun 2026

Scientists Identify Epigenetic Mechanism Behind Lifelong Maternal Brain Modifications

Becoming a mother changes the brain not just temporarily, but for life.

5 Jun 2026

Genetic Blueprint Framework Maps Insect Brains to Simplify Human Neuroscience

While E. Josie Clowney would never suggest that neuroscience is simple, a new study by her team at the University of Michigan could drastically reduce complexity in future studies.

4 Jun 2026

New Chromosome Packaging Discovery Explains Unlimited Growth in Cancer Cells

Published today in Nature, researchers at the University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center report a previously unrecognized change in how the cell's genetic material is packaged into structures called chromosomes.

4 Jun 2026

New Gene-Editing Strategy Ensures Quality Control in Stem Cell Therapies

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing.

3 Jun 2026

How Tiny Molecular Tethers Prevent Plant Cells From Crumpling

Water deficit resistance in plants has long been a topic of interest for cultivating reliable crops.

3 Jun 2026

Scientists Uncover How Marine Invertebrates Bypass Mammalian Epigenetic Rules

Typically, the information encoded in DNA allows organisms to develop, function and pass traits across generations.

3 Jun 2026

Scientists Decode How T Cells Stop Deadly Viruses

T cells are among the immune system’s essential soldiers. They can inhibit tumor development and even combat serious infections.

3 Jun 2026

Bispecific Antibodies Target Tumors While Sparing Healthy Tissue

A new generation of bispecific antibodies effectively targets cancer cells, minimizing toxicity and enhancing treatment precision in preclinical studies.

3 Jun 2026

Atomic Snapshots of Human SMUG1 Unveil the Secrets of DNA Repair

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA.

3 Jun 2026

A New Non-Destructive Tool Maps Active Transcription Profiles in Living Tissue

Cell function is determined by how DNA is expressed into proteins. That process includes two main steps - transcription, when messenger RNA (mRNA) makes copies of active genes, and translation, when mRNA guides protein assembly.

2 Jun 2026

Intact Gut Microbes Accelerate Selenium Excretion to Protect Against Toxic Overload

Selenium is an essential micronutrient that supports antioxidant and immune functions, yet how its metabolism is regulated by interactions between host and gut microbiota remains unclear. In a recent study, researchers from Japan used rats to investigate how gut microbiota and the host jointly manage selenium metabolism.

2 Jun 2026