Molecular & Structural Biology

RSS

Living Organisms Depend on Bacterial Production of Critical Vitamin B12

All living organisms need a little bit of it to form red blood cells and DNA, as well as to build and support brain and nerve cells. But it's hard to come by: Humans don't make it. Animals don't make it. Plants don't make it.

7 Aug 2026

Modulating T Cell Exhaustion Offers Novel Therapeutic Pathways in Transplantation

A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this dysfunctional immune state can both promote graft tolerance and create vulnerabilities to infection and malignancy.

7 Aug 2026

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

A new review highlights the growing importance of circular RNAs (circRNAs) in addressing one of the most pressing challenges in modern oncology: treatment-related toxicity.

6 Aug 2026

Blood Immune Cells Cross Protective Barriers to Transform Aging Brains

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Cells can switch off genes by tightly packaging DNA around proteins called histones.

6 Aug 2026

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Researchers at Mayo Clinic have identified a protein that cancer cells use to suppress the body's immune response, a finding that could support the development of new treatments to improve the effectiveness of cancer immunotherapies.

5 Aug 2026

Mapping Spatial Genome Architecture Unlocks Hidden Biological Mechanisms Behind Genetic Risk

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA sequence.

5 Aug 2026

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

New Analytical Framework Captures Coordinated Host and Microbial Disease Responses

The trillions of microorganisms living in our intestine influence our health, from digestion and metabolism to immunity.

5 Aug 2026

Genetic and Environmental Factors Shape Crucial Cell Fitness Level Variations

How readily a cell divides and how well it survives is fundamental to life, shaping everything from organ size to the body’s ability to withstand disease.

5 Aug 2026

Researchers Track Genetic Mutation Clues Behind Accelerated Aging Vascular Decline

Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature ageing. Most patients die during their teenage years from cardiovascular disease, but the precise mechanisms underlying vascular damage remain unclear.

5 Aug 2026

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases.

3 Aug 2026

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Salt stress is one of the most destructive environmental threats to crop production, causing osmotic imbalance, ion toxicity, and oxidative damage that stunt growth and reduce yields.

3 Aug 2026

Joint Research Team Demonstrates New Cell Sequencing Strategy for Glioblastoma

A joint research team led by Professor Sungsu Park of Sungkyunkwan University and Professor Sun-Ha Paek of Seoul National University College of Medicine has demonstrated for the first time that the sequence in which immune cells interact with cancer cells can critically influence the therapeutic response in glioblastoma.

3 Aug 2026

Uncovering New Pathological Pathways Behind Sepsis Triggered Circulatory Failure Risks

Sepsis triggers widespread inflammation, circulatory failure and metabolic stress, and cardiac dysfunction is a common complication associated with sharply poorer outcomes.

3 Aug 2026

Researchers Identify Neurons Responsible for Regulating Motivated Behavior

What enables us to sustain effort toward goals, even when the task becomes increasingly difficult? A recent study by researchers at Nagoya University in Japan revealed the underlying brain mechanism, showing that orexin neurons play a crucial role in driving and regulating motivated behavior.

3 Aug 2026

Innovative SenMayo Gene Set Consistently Identifies Diverse Senescent Cells

A series of seven Mayo Clinic studies is helping reshape scientists' understanding of senescent, or "zombie," cells - aging cells that no longer divide but remain metabolically active and release inflammatory molecules that contribute to age-related diseases.

31 Jul 2026

Northwestern Chemists Repurpose Flexible DNA as Programmable Molecular Glue

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.

30 Jul 2026

New Method Enables Faster Oxidation-Free Oligonucleotide Synthesis

Oligonucleotide synthesis is fundamental to genetic analysis, biological research, and nucleic acid therapeutics.

30 Jul 2026

Molecular & Structural Biology

Living Organisms Depend on Bacterial Production of Critical Vitamin B12

Modulating T Cell Exhaustion Offers Novel Therapeutic Pathways in Transplantation

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

Blood Immune Cells Cross Protective Barriers to Transform Aging Brains

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Mapping Spatial Genome Architecture Unlocks Hidden Biological Mechanisms Behind Genetic Risk

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

New Analytical Framework Captures Coordinated Host and Microbial Disease Responses

Genetic and Environmental Factors Shape Crucial Cell Fitness Level Variations

Researchers Track Genetic Mutation Clues Behind Accelerated Aging Vascular Decline

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Joint Research Team Demonstrates New Cell Sequencing Strategy for Glioblastoma

Uncovering New Pathological Pathways Behind Sepsis Triggered Circulatory Failure Risks

Researchers Identify Neurons Responsible for Regulating Motivated Behavior

Innovative SenMayo Gene Set Consistently Identifies Diverse Senescent Cells

Northwestern Chemists Repurpose Flexible DNA as Programmable Molecular Glue

New Method Enables Faster Oxidation-Free Oligonucleotide Synthesis

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Cosmetic Formulation and Manufacturing

Selecting a Benchtop Fluorescence Microscope: Key Considerations for Your Lab

Biopharmaceuticals

Latest in Genomics