Molecular & Structural Biology

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New Ring Structure Guides Precise Cell Death and Immunity

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms.

16 Mar 2026

NuSAP Protein Safeguards Centriole Structure During Cell Division

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental disorders such as microcephaly and mosaic variegated aneuploidy (MVA) syndrome.

13 Mar 2026

Capsule Technology Enables Multi-Step Analysis of Individual Living Cells

Researchers have developed a capsule-based method that makes it possible to analyze the same cell through multiple experimental steps.

13 Mar 2026

Study Reveals How Altering Cancer’s Protein Machinery Stimulates Antitumor Immunity

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response.

12 Mar 2026

Transposable Elements Found Responsible for Most Lethal Fly Mutations

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

11 Mar 2026

How SARS-CoV-2 Hijacks Host tRNA Chemistry to Sustain Infection

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

11 Mar 2026

Three CBX2 Molecules Found to Orchestrate Essential Stem Cell Fate Decisions

A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large‑scale gene-silencing structures inside cells, and what happens when that process breaks down.

6 Mar 2026

Plant Protein Structure Provides New Insights Into Human Cancer and Better Crops

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in human disease.

6 Mar 2026

Study Maps the Complete Genetic Blueprint for Loganin Biosynthesis

Plant-derived terpenoids play essential roles in medicine, agriculture, and human health, but their biosynthesis is often complex and tightly regulated.

5 Mar 2026

Study Demonstrates Information Exchange Between Right-Handed and Mirror DNA

A new study by NYU chemists finds that DNA tiles can assemble into 3D structures without the sticky cohesion of hydrogen bonding. This finding, published in Nature Communications, turns a fundamental paradigm in the field of DNA self-assembly on its head.

3 Mar 2026

How Catalytic RNA Redefined Enzymes and the Origin of Life

There have been many important discoveries along the path to what we know today about RNA, or ribonucleic acid-a molecule found in every living cell that helps carry and interpret genetic instructions.

2 Mar 2026

Promega Unveils Cellular Target Engagement Technology Aimed at Expanding the Druggable Proteome at SLAS 2026

Promega Corporation is launching a new live-cell target engagement platform that could close a long-standing gap between biochemical and cellular assays for understudied or difficult-to-interrogate proteins.

27 Feb 2026

Structural Blueprint of Cellular Biomolecular Condensates Opens New Therapeutic Possibilities

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

26 Feb 2026

Scientists Discover Unique Chromosome Reorganization in Developing Germ Cells

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic precursors of these cells uniquely reshape the 3D organization of their genetic material.

23 Feb 2026

Brain Enzymes MNK1 and MNK2 Regulate Distinct Behaviors in the Brain

Researchers at the Max Delbrück Center show that two related enzymes, MNK1 and MNK2, act on the brain to regulate different behaviors.

20 Feb 2026

Scientists Map Protein Production Across Individual Brain Cells

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

19 Feb 2026

Study Reveals New Structural Role for HIV Integrase

The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.

19 Feb 2026

Chemical Tweaks Boost Peptide Stability and Antimicrobial Power

Antibiotic treatments are losing effectiveness against a range of common bacterial pathogens, including E. coli, K. pneumoniae, Salmonella and Acinetobacter, according to a warning issued by the World Health Organization last October.

16 Feb 2026

Protrusion-Derived EVs Boost Protein Delivery Efficiency

Extracellular vesicles (EVs) are tiny membrane-bound particles released by cells to transport proteins and other molecules to neighboring cells. Because of this natural delivery ability, EVs have attracted growing interest as potential vehicles for therapeutic protein and genome-editing enzyme delivery.

16 Feb 2026

Mapping the Binding Energy of Histamine Receptors

G-protein-coupled receptors (GPCRs) are one of the biggest groups of cell surface proteins in the human body, recognizing hormones, neurotransmitters, and drugs.

16 Feb 2026