Molecular & Structural Biology

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Stimulating Early Brain Circuits Partially Restores Vocal Defects Caused by Genetic Mutations

Communication begins long before children learn to speak. Researchers at National Yang Ming Chiao Tung University (NYCU) in Taiwan have now uncovered how early brain activity helps build developing communication circuits via regulating FOXP2/Foxp2, a gene linked to human speech and communication disorders.

20 May 2026

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma.

20 May 2026

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient cell functions.

20 May 2026

Scientists Design Decoy Peptides to Prevent Chronic Overactivation of Immune Cells

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers.

19 May 2026

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore), has identified eight new "signatures" of DNA patterns (gains and/or losses) in breast cancer.

19 May 2026

Dual-Action Protein Found to Fuel and Repair Cancer

According to a recent study, a protein best known for fueling cancer development also aids in the survival of damaged tumor cells by repairing their DNA, which might impact how certain cancers are treated.

18 May 2026

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

A new study published in Engineering has established an absolute quantification strategy for immunoglobulin G (IgG) N-glycans linked to aging, providing a reliable method to assess biological age and explore anti-aging interventions.

15 May 2026

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

15 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

Nanoscopy Technique Reveals Hidden Networks Cells Use to Communicate

The Australian National University (ANU) has created a new nanoscopy technology that has revealed secret networks utilized for cell-to-cell communication, providing fresh insights into human disorders.

15 May 2026

Supercomputer Simulations Map Sodium Pumping in Pathogenic Bacteria

The Na+-NQR enzyme is vital for energy production in pathogenic bacteria like the one that causes cholera, making it a highly promising target for new antibiotics.

15 May 2026

Novel RNA Analysis Method Supports Antiviral Drug Discovery

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair.

14 May 2026

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Cryo-EM Study Explains Why Coffee Tastes Bitter to Humans

Have you ever wondered why freshly brewed coffee smells so delicious, but tastes bitter?

12 May 2026

Cryo-EM Images Reveal Coronavirus Proofreading Enzyme in Atomic Detail

The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more effective treatment of the disease.

8 May 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

New Pistoia Alliance Poll Finds Regulatory Teams Benefit Most from AI, But Just 1 % See Value in the Wet Lab

The Pistoia Alliance, a global, not-for-profit that advocates for greater collaboration in life sciences R&D, has released new poll data from its annual European conference, revealing that while AI use is becoming widespread across life sciences organizations, its measurable impact on drug R&D remains limited.

From The Pistoia Alliance 29 Apr 2026

Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics

Proxygen, a biotechnology company pioneering the discovery of molecular glue degraders and next-generation proximity-based therapeutics, today publicly announced the expansion of its platform beyond targeted protein degradation to access a broader range of induced proximity therapeutics, while advancing two lead molecular glue degrader programs toward clinical development.

From Proxygen 29 Apr 2026

Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk

The study identifies PRRX1 as a critical factor in breast cancer metastasis, highlighting its potential as a biomarker for predicting aggressive disease.

29 Apr 2026

Molecular & Structural Biology

Stimulating Early Brain Circuits Partially Restores Vocal Defects Caused by Genetic Mutations

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Scientists Design Decoy Peptides to Prevent Chronic Overactivation of Immune Cells

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

Dual-Action Protein Found to Fuel and Repair Cancer

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

Animals Adapt Rapidly Through Protein Networks, Not Genes

Nanoscopy Technique Reveals Hidden Networks Cells Use to Communicate

Supercomputer Simulations Map Sodium Pumping in Pathogenic Bacteria

Novel RNA Analysis Method Supports Antiviral Drug Discovery

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Cryo-EM Study Explains Why Coffee Tastes Bitter to Humans

Cryo-EM Images Reveal Coronavirus Proofreading Enzyme in Atomic Detail

How the Microbiome Shapes Cancer Immunity and Therapy Response

New Pistoia Alliance Poll Finds Regulatory Teams Benefit Most from AI, But Just 1 % See Value in the Wet Lab

Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics

Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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