Cell Biology News and Research

Latest Cell Biology News and Research

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the biosynthesis of downstream products ranging from neurotransmitters and plant hormones to dyes and complex alkaloids.

8 Jan 2026

Cooperation's Fate: Population Bottlenecks Reshape Microbial Social Dynamics

Microbes often display cooperative behavior in which individual cells put in work and sacrifice resources to collectively benefit the group.

8 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Mitochondria Transfer Eases Chronic Nerve Pain

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

High-Tech Imaging Unlocks Genetic Secrets Of Nutrient-Rich Seeds

By rapidly analyzing nearly 12,000 individual seeds, the approach uncovers genetic loci that simultaneously influence seed morphology and mineral composition, opening new avenues for crop biofortification and safer food production.

7 Jan 2026

Identifying Molecules That Activate and Inhibit Key Protein Function

Researchers at Northwestern University have discovered a concealed molecular "control switch" within a protein that plays a crucial role in the body's ability to perceive taste, regulate blood sugar, and protect the gut.

7 Jan 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Dual Genetic Mutations Drive RNA Mis-Splicing and Leukemia Progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic mutations – IDH2 and SRSF2 – work cooperatively to mis-splice RNA messages and change how blood cells develop.

6 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

Hidden Molecular "Control Switch" Uncovered Inside TRPM5 Protein

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body sense taste, control blood sugar and defend the gut.

6 Jan 2026

LINE-1 Retrotransposons Reshape Cancer Genome Architecture

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

6 Jan 2026

Tumor Bacteria Found to Drive Immunotherapy Resistance

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

5 Jan 2026

Scientists Develop Noise Controller to Tame Random Cell Behavior

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

5 Jan 2026

New Method Turns Glial Cells Directly Into Parvalbumin Neurons

Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signaling, reduce overactivity and make sure that the brain is working to a rhythm.

5 Jan 2026

New CHANGE-seq-BE Method Sharpens Safety Assessment of CRISPR Base Editors

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital.

5 Jan 2026

Single-Donor Lung-on-Chip Enables Personalized TB Research

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

m-RNA and Immunostimulant Activate CAR-Macrophages in Cancer Cells to Fight Cancer

Immune cells (macrophages) capable of combating cancer exist within tumors in the human body, but they are unable to fulfill their functions adequately due to tumor suppression.

2 Jan 2026

New ddHodge Method Reconstructs Cell Fate Dynamics with High Accuracy

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature Communications, this approach paves the way for a deeper understanding of the biological processes involved in development, regeneration, and disease.

30 Dec 2025

Mitochondrial Protein That “Erases” Huntington’s Aggregates

DGIST has made a groundbreaking announcement: a research team, under the guidance of professors Jiwon Um and Jaewon Ko, has achieved a global first by elucidating the function of ‘ClpB.’

29 Dec 2025