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Novel lung phantom mimicking pulmonary optical properties may enable air volume assessment

Take a nice, deep breath. Now imagine your lungs: myriad airways like branches, each with tiny alveoli like leaves. This alveolar structure is key to the absorption of oxygen and excretion of carbon dioxide that we call "breath."

2 Nov 2021

Researchers develop new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection then triggers production of a specific protein from a transgene, or artificial gene.

From Massachusetts Institute of Technology (MIT) 29 Oct 2021

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Ghent University’s concentrated on a technique for the safe engineering of therapeutic cells with photothermal nanofibers for the past decade.

26 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Cambridge researchers have discovered how T cells – an important component of our immune system – are able keep on killing as they hunt down and kill cancer cells, repeatedly reloading their toxic weapons.

15 Oct 2021

Researchers develop key components of an expanded genetic code system

Modern biologists nurture more ambitious goals and one among them is to know how to broaden or alternatively modify the genetic code of life on Earth.

1 Oct 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

High fat diets lead to over-eating and obesity in rats by disturbing the body clock

When rats are fed a high fat diet, this disturbs the body clock in their brain that normally controls satiety, leading to over-eating and obesity. That's according to new research published in The Journal of Physiology.

7 Sep 2021

Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

Researchers develop a method to engineer new functionalities into cells

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have developed a method to engineer new functionalities into cells. The results were published today in the journal Cell in the article "Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation".

26 Aug 2021

Study devises novel process to purify exosomes from cow’s milk

Cells produce exosomes, the nano-sized biological capsules, to protect and courier delicate molecules across the body. The capsules are hard enough to resist enzymatic breakdown and acidic and temperature fluctuations in the bloodstream and gut, which makes them a major candidate for drug delivery.

25 Aug 2021

Translation News and Research

Novel lung phantom mimicking pulmonary optical properties may enable air volume assessment

Researchers develop new approach to selectively turn on gene therapies in target cells

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Researchers map proteo-genomic connections between different human diseases

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Researchers develop key components of an expanded genetic code system

Tumor suppressor protein binding to RNA also binds DNA, says study

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

Researchers reveal why nerve cell’s protein production slows down in CMT patients

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

High fat diets lead to over-eating and obesity in rats by disturbing the body clock

Experts decode the genetic mechanism governing the speed of mRNA translation

Researchers develop a method to engineer new functionalities into cells

Study devises novel process to purify exosomes from cow’s milk

Study analyzes the role of eIF4A3 protein in cancer cell growth

Cytokines play a role in regulation of beige fat

New collaboration to support start-up companies in regenerative medicine space

New formulation to administer antibodies for choroidal neovascularization therapy

Study unravels gene expression control mechanism with immunity and cancer implications

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