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New approach to rapidly determine biological aging

Telomeres-;the caps at the ends of chromosomes that protect our genetic materials from the brunt of cellular wear and tear-;are known to shorten and fray over time.

16 Feb 2023

Novel mechanism of DNA repair occurring in neurons uncovered

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.

16 Feb 2023

The essential protein needed for immune evasion and tumor cell metabolism

Typically, tumor cells change their energy metabolism and take in more glucose to enable their rapid division and spread. As a result, the body’s immune response to cancer is suppressed by limiting the immune cells’ access to glucose.

15 Feb 2023

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

3 Feb 2023

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity."

1 Feb 2023

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.

1 Feb 2023

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

30 Jan 2023

Experts urge to recognize the need for more rational discourse around the future of virology

The study of viruses is under renewed scrutiny, say more than 150 experts in a new commentary published today in mSphere, mBio and the Journal of Virology, journals of the American Society for Microbiology.

27 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Investigating the molecular mechanisms that govern cilia force sensing

Although the human body is superficially symmetric along the left–right axis, most internal organs, including the heart, lungs, liver, stomach, and brain, have noteworthy left–right asymmetries in their structure and placement.

6 Jan 2023

MIT researchers use specialized MRI sensor to detect light deep within tissues

Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain.

3 Jan 2023

Genetic cause behind novel DEE syndrome discovered

Autism and epilepsy are two highly prevalent conditions that fall under the umbrella of neurodevelopmental disorders (NDD), which affect 1–3% of the world’s population just in terms of cognitive disabilities.

20 Dec 2022

New DNA analysis leads to first accurate tuberculosis genome identification

A novel genome assembly tool that has been created by researchers could lead to the creation of fresh antibiotics for the bacterial infections that cause tuberculosis and other diseases.

From Rutgers University 20 Dec 2022

Octopuses' acuity may provide a critical link in understanding the evolution of complex life

Octopuses have captured the attention of scientists and the public with their remarkable intelligence, including the use of tools, engaging in creative play and problem-solving, and even escaping from aquariums.

16 Dec 2022

New information to combat the global challenge of AMR

An international research team has released important new information about what causes the emergence and spread of genes involved in antimicrobial resistance (AMR) in bacteria.

14 Dec 2022

Figuring out how immune cells prevent cognitive decline

Could Alzheimer’s disease and other types of cognitive decline be caused by the underproduction of immune cells that are poorly understood? It might, according to a Rutgers study published in Nature Immunology, and increasing these cells could undo the harm.

From Rutgers University 1 Dec 2022

Acute infection disrupts the healthy balance between the good and bad gut microbes

Rutgers researchers examined the impact of COVID-19 on patients’ microbiomes, the group of microbes that live in and on the human body.

From Rutgers University 30 Nov 2022

Highlighting the potential of new techniques to study mental disorders

Researchers investigating the fundamental brain mechanics of autism spectrum disorder have discovered that a gene mutation known to be connected with the illness causes considerably more overstimulation of brain cells than in neuronal cells without the mutation.

23 Nov 2022

Chemically attenuated live DNA virus vaccine prevents viral infection

Rutgers researchers have devised a new way to prevent viral infections: a live-attenuated, replication-defective DNA virus vaccine that utilizes the substance centanamycin to create an altered virus for vaccine development.

From Rutgers University 22 Nov 2022

A gene’s function in embryonic development

An international study led by the medical school at the University of Bonn has discovered a gene that is crucial to the growth of the human embryo. Abnormalities of different organ systems may occur if it is changed.

16 Nov 2022