RNA Sequencing News and Research

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A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

Scientists develop a new approach that efficiently integrates information from parallel gene-expression profiling methods at single-cell resolution.

23 Mar 2022

New map tracks cellular trajectories across mouse embryogenensis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

15 Mar 2022

T cells sometimes remain in the skin for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

8 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022

New and unconventional nuclear function for oncogenic microRNA discovered

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

MIT researchers create a new cerebrovasculature atlas

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

16 Feb 2022

Researchers discover DisCo for effective processing of samples with fewer cells

Single-cell RNA sequencing is an approach that lets researchers to study the gene expression in an individual cell within a mixed population.

16 Feb 2022

Single-cell sequencing technique helps to examine early SARS-CoV-2 infection

In the early days of SARS-CoV-2 infection in the lungs, what happens at the single-cell level?

14 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

Different autism risk genes have similar effects on brain development, study finds

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

3 Feb 2022

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Researchers have explored the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, and breast cancer.

31 Jan 2022

Researchers identify changes in gene expression and cellular interactions in COPD lung cells

Researchers at Baylor College of Medicine, Yale University and other institutions have identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive pulmonary disease (COPD).

28 Jan 2022

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown.

28 Jan 2022

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.

17 Dec 2021

Research offers alternative cell option for organs-on-chips

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

13 Dec 2021

Experts create world’s first single-cell atlas of human and porcine eyes

Researchers recently constructed the first single-cell atlas of the human and porcine eyes.

8 Dec 2021

MIT researchers identify a way to indirectly activate T cells to fight tumors

Under the right circumstances, the body's T cells can detect and destroy cancer cells. However, in most cancer patients, T cells become disarmed once they enter the environment surrounding a tumor.

22 Nov 2021

RNA Sequencing News and Research

A critical subset of supporting cells may lie at the origins of scleroderma

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

New map tracks cellular trajectories across mouse embryogenensis

T cells sometimes remain in the skin for years, research finds

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Men and women do have immune cell differences, study says

Why is it Important to have Diverse Genomics Data in Science?

New and unconventional nuclear function for oncogenic microRNA discovered

MIT researchers create a new cerebrovasculature atlas

Researchers discover DisCo for effective processing of samples with fewer cells

Single-cell sequencing technique helps to examine early SARS-CoV-2 infection

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

Different autism risk genes have similar effects on brain development, study finds

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Researchers identify changes in gene expression and cellular interactions in COPD lung cells

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Research offers alternative cell option for organs-on-chips

Experts create world’s first single-cell atlas of human and porcine eyes

MIT researchers identify a way to indirectly activate T cells to fight tumors

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