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Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Researchers find a new way to counter immunosuppressive effect in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

21 Sep 2021

Changes in epigenome responsible for reduced stem cell function upon aging

The bones become thinner with age, resulting in frequent fractures and making them susceptible to bone diseases like osteoporosis.

From The Max Planck Institute 20 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

New algorithm can identify diseased cells for personalized treatment

Scientists have created an innovative artificial intelligence algorithm known as “scArches” for clinical applications.

1 Sep 2021

Study reveals mechanisms promoting overall glioma tumor growth

Researchers from Northwestern Medicine unearthed the epigenetic processes involved in the regulation of multiple oncogenes in glioma cells.

31 Aug 2021

Old habit-controlling neurons may also play a key role in learning new tricks

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021

Newly developed premature cells can support early heart development

A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.

23 Aug 2021

Genomic surveillance is vital to achieve effective mitigation and containment of COVID-19

Although the development and increasingly widespread availability of effective and safe vaccines provides the greatest hope for the future recovery from the increasingly devastating COVID-19 pandemic, genomic surveillance is emerging as a vital necessity to achieve effective mitigation and containment.

19 Aug 2021

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

Modification in some RNA molecules could protect against non-alcoholic fatty liver

RNA molecules while carrying genetic instructions from DNA to the protein-making machinery of cells could help guard against non-alcoholic fatty liver.

21 Jul 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

19 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Surgery News and Research

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

Genetic and epigenetic origin of pediatric liver cancer uncovered

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

Researchers find a new way to counter immunosuppressive effect in tumors

Changes in epigenome responsible for reduced stem cell function upon aging

Genetically engineered cells deliver drugs in response to inflammation

New algorithm can identify diseased cells for personalized treatment

Study reveals mechanisms promoting overall glioma tumor growth

Old habit-controlling neurons may also play a key role in learning new tricks

Newly developed premature cells can support early heart development

Genomic surveillance is vital to achieve effective mitigation and containment of COVID-19

Study: Biomarker can predict response to immunotherapies in breast cancer patients

Modification in some RNA molecules could protect against non-alcoholic fatty liver

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

Gene therapy may be safe and effective in treating AADC deficiency

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Liver fibrosis might be treatable with selective immunotoxins

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Universal stem cells exhibit the potential for more cost-effective cell therapy

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