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Tool to control cellular activity could advance biology and medicine

A cell’s ability to react to its surroundings is one of its fundamental roles. Therefore, it makes sense that one of the objectives of scientists is to manipulate that process so that cells react to their desires.

5 Dec 2024

From Yeast to Humans: Decoding the Link Between Nucleolar Size and Aging

Research reveals that nucleolar enlargement in yeast disrupts genomic integrity, linking size to lifespan and offering insights into aging mechanisms.

5 Dec 2024

Research Sheds Light on Protein's Role in Enhancing Plant Disease Resistance

Salicylic acid is vital for protecting plants from pathogens, but its synthesis remains unclear. A recent study by Shinshu University researchers has discovered that the protein HSR201 is key to its production.

3 Dec 2024

Enterococcus Co-Infection Increases Protective Slime in Pathogenic E. coli

A new study finds that two subtypes of pathogenic Escherichia coli (E. coli) produce five to 16 times more protective capsular "slime" when Enterococcus faecalis (EF) is present.

3 Dec 2024

New Artificial Adhesion System Closely Mimics Natural Biological Interactions

In a first-of-its-kind breakthrough, a team of UBC Okanagan researchers has developed an artificial adhesion system that closely mimics natural biological interactions.

3 Dec 2024

New Discovery Redefines the Shape of Axons in Mammalian Brain Cells

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

3 Dec 2024

The Critical Role of TRiC in Brain Development and Function

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

29 Nov 2024

Systemic Metabolic Adaptation Supports Tissue Regeneration in Axolotls and Fruit Flies

Regenerating tissues following injury is a demanding task most multicellular organisms master to different levels. In order to better understand the mechanisms common to many species behind tissue regeneration, researchers from the Paul Langerhans Institute Dresden and the BIOTEC (TU Dresden), decided to examine changes in systemic metabolism during regeneration.

29 Nov 2024

Stanford Researchers Develop New Approach to Make Cancer Cells Self-Destruct

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

28 Nov 2024

Genetic Signatures Driving Early Type 2 Diabetes in South Asians Revealed

A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people.

28 Nov 2024

Novel DNA-Based Platform for Biomolecular Interactions

Researchers at The University of British Columbia Okanagan have created a first-of-its-kind artificial adhesion system that closely resembles biological connections.

28 Nov 2024

Novel Fungal Commensal Shaping Mouse Immune Responses

Researchers from Weill Cornell Medicine have found a fungus in the stomach of mice that may provide a clue to the evolution of fungi in the gastrointestinal tract.

28 Nov 2024

Mitochondria Found to Play Key Role in Balancing Cell Death and Inflammatory Response

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria.

27 Nov 2024

Study Reveals Molecular Mechanism Behind Neural Fate Commitment

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development -; which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

Study Links MICOS10 Gene Defect to Mitochondrial DNA Depletion Syndrome

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

27 Nov 2024

New Tool to Unravel the Secrets of Malaria Parasite Adhesion

To better understand the highly varied characteristics that enable malaria parasites to adhere to red blood cells and elude the immune system, researchers have developed a new tool.

27 Nov 2024

Unveiling the Epigenetic Landscape of Blood Cancers

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes.

27 Nov 2024

Single-Cell Analysis Sheds Light on Leukemia Cell Heterogeneity

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

26 Nov 2024

New Imaging Method Unlocks Secrets of RNA Folding Dynamics

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of individual RNA nanoparticles in the midst of their folding process.

26 Nov 2024

Dopamine and Serotonin Act as Opposing Forces in Learning and Reward

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work -; it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

26 Nov 2024