Immunology News and Research

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Immunology is the study of the body's immune system.

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Insilico Medicine, a clinical-stage biotech company powered by generative AI, today announces that China National Medical Products Administration (NMPA) has approved the Investigational New Drug (IND) application for ISM3312, an orally available 3CLpro inhibitor generated and designed with the support of Insilico's proprietary generative chemistry platform Chemistry42 for the treatment of COVID-19.

24 Feb 2023

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

A new Australian study led by SAHMRI and Flinders University has uncovered fundamental differences in how the AstraZeneca and Pfizer COVID-19 vaccines impact the immune system.

23 Feb 2023

Mount Sinai researchers reveal mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

23 Feb 2023

Study shows how convalescent plasma can be used as effective treatment during future pandemics

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe.

22 Feb 2023

New biomarker helps identify biological age

Once considered to be incompetent in encoding proteins due to their simple monotonous DNA repetitions, tiny telomeres at the tips of human chromosomes now appear to have a powerful biological function that could help better understand cancer and aging.

21 Feb 2023

Novel metabolic pathway that makes immunology more efficient revealed

The metabolic pathways that produce a specific type of T cell are distinct from previously assumed, according to findings from the University of Michigan Rogel Cancer Center.

21 Feb 2023

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

A biomedical researcher at the Lankenau Institute for Medical Research (LIMR), part of Main Line Health, has created a groundbreaking resource for scientists seeking to develop new and better vaccines in the fight against COVID-19.

19 Feb 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

PFAS chemical helps suppress the neutrophil respiratory burst, study finds

In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.

16 Feb 2023

LJI receives funding from NIAID to lead the biggest human immunoprofiling effort

A new grant of over $17 million from the National Institute of Allergy and Infectious Diseases (NIAID) has established La Jolla Institute for Immunology (LJI) as the leading institute for human immunology data curation, analysis, and dissemination. With this funding, LJI has taken the helm of the Human Immunology Project Consortium Data Coordinating Center, a critical tool in the effort to fuel scientific collaboration in immunoprofiling and highlight findings from the overall Human Immunology Project Consortium (HIPC).

16 Feb 2023

Blastocystis can promote or disrupt gut health, study finds

The gut microbiota contains trillions of bacteria that can promote health or cause disease under different conditions.

14 Feb 2023

Review highlights the pathological significance of CEACAM1, 5, and 6

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

14 Feb 2023

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

13 Feb 2023

Tissue inflammation altered by “natural killer” immune cells

The discovery of a previously unknown role of “natural killer” (NK) immune cells by Melbourne researchers has increased the current understanding of how the immune system is controlled to prevent disease.

13 Feb 2023

Importance of epigenetic regulation in the recovery of T cells

In stem cell transplants for leukemia treatment, the patient’s hematopoietic system is removed and replaced with hematopoietic cells from donors.

10 Feb 2023

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

10 Feb 2023

Novel compound curtails influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

10 Feb 2023

Protein that facilitates cancer-causing viruses dodge the immune system

Numerous cancers have been related to the viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV). For the first time, UNC School of Medicine researchers have shown that these viruses elude the innate immune response by using a human protein called barrier-to-autointegration factor 1, or BAF, which enables the viruses to propagate and cause disease.

7 Feb 2023

Newly discovered gene signature accurately predicts the functioning of P53 variants

In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

7 Feb 2023

Scientists discover how a high fat diet expels gut parasitic worm

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

Immunology News and Research

Further Reading

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

Mount Sinai researchers reveal mechanisms underlying autoimmunity in Down syndrome

Study shows how convalescent plasma can be used as effective treatment during future pandemics

New biomarker helps identify biological age

Novel metabolic pathway that makes immunology more efficient revealed

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

CD5-expressing dendritic cells help to prime T cell responses against cancer

PFAS chemical helps suppress the neutrophil respiratory burst, study finds

LJI receives funding from NIAID to lead the biggest human immunoprofiling effort

Blastocystis can promote or disrupt gut health, study finds

Review highlights the pathological significance of CEACAM1, 5, and 6

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Tissue inflammation altered by “natural killer” immune cells

Importance of epigenetic regulation in the recovery of T cells

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

Novel compound curtails influenza virus replication

Protein that facilitates cancer-causing viruses dodge the immune system

Newly discovered gene signature accurately predicts the functioning of P53 variants

Scientists discover how a high fat diet expels gut parasitic worm

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