Research News and Research

RSS

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Potential approach to improve solid tumor T cell therapy

Researchers at the Perelman School of Medicine at the University of Pennsylvania have been working on a preclinical study that focuses on a new strategy that uses a “one-two punch” to assist T cells in attacking solid tumors.

17 Mar 2023

The impact of genome doubling on the development of cancer

Since a single cell has 2–3 m of DNA, the only method to store it is in tight coils. The answer is chromatin, a DNA-protein complex that is wrapped around histone proteins.

17 Mar 2023

Highlighting a potential sex‐specific precision immunotherapy strategy

Immunotherapy is an effective form of treatment for various types of cancer. However, its effect on pancreatic cancer is restricted and varies between men and women. Karolinska Institutet scientists have observed a possible explanation for this gender difference.

17 Mar 2023

Emergence and spread of a deadly fungus among African amphibians

For the past few years, how a virus triggered a global pandemic has dominated conversations. Now, thanks to the TV show "The Last of Us" (about an apocalypse triggered by brain-eating 'shrooms), fungi have infected popular culture.

16 Mar 2023

Spatial Computing theory could explain the brain's flexible working memory

Brain applies rhythms to physical patches of the cortex to selectively control just the right neurons at the right times to do the right things.

16 Mar 2023

Unique region of the brain's cortex used when visually navigating an area by foot

Using vision to efficiently move through an area by foot uses a unique region of the brain's cortex, according to a small study funded by the National Eye Institute.

16 Mar 2023

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

16 Mar 2023

Influence of molecular component of caffeine on gut health

Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).

16 Mar 2023

Study reveals: Coronaviruses that cause common colds boost immune response to COVID-19

During the pandemic, it became clear that children who contracted COVID-19 became less ill than adults. One hypothesis has been that common colds would give children immunity protecting against a severe form of the disease. Researchers at Karolinska Institutet are now able to show that OC43, one of the coronaviruses that cause common colds, boosts the immune response to COVID-19. The study, which is published in PNAS, could give rise to more tailored vaccine programmes for children and adults.

16 Mar 2023

Novel web-based tool deoptimizes genetic sequences based on different codon usage

A new software tool developed by Texas Biomedical Research Institute and collaborators can help scientists and vaccine developers quickly edit genetic blueprints of pathogens to make them less harmful.

16 Mar 2023

Study reveals the cellular composition and circuit organization of the locus coeruleus

A small nucleus in the brainstem called locus coeruleus (literally the "blue spot,") is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the 'fight or flight' response in animals. However, very little is known about the local connections of this small albeit critically important group of neurons.

16 Mar 2023

High doses of sucralose limit T cell proliferation and differentiation

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

16 Mar 2023

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

16 Mar 2023

Novel newborn screening test for HCU works by measuring homocysteine levels

Scientists have developed a test that could greatly improve quality of life for infants with homocystinuria (HCU)-;a congenital disease that, if not treated early, causes serious complications. Research demonstrating the efficacy of this test was published today in AACC's Clinical Chemistry journal.

16 Mar 2023

First molecular images of olfaction sets the stage to create novel smells

Breaking a longstanding impasse in our understanding of olfaction, scientists at UC San Francisco (UCSF) have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.

16 Mar 2023

Research News and Research

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Potential approach to improve solid tumor T cell therapy

The impact of genome doubling on the development of cancer

Highlighting a potential sex‐specific precision immunotherapy strategy

Emergence and spread of a deadly fungus among African amphibians

Spatial Computing theory could explain the brain's flexible working memory

Unique region of the brain's cortex used when visually navigating an area by foot

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Influence of molecular component of caffeine on gut health

Study reveals: Coronaviruses that cause common colds boost immune response to COVID-19

Novel web-based tool deoptimizes genetic sequences based on different codon usage

Study reveals the cellular composition and circuit organization of the locus coeruleus

High doses of sucralose limit T cell proliferation and differentiation

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

Novel newborn screening test for HCU works by measuring homocysteine levels

First molecular images of olfaction sets the stage to create novel smells

Study examines the role of dietary vitamin A in preventing or treating AAP

Age-related sarcopenia prevented by AAV1.NT-3 gene therapy

Study: Cultivating edible fungi alongside trees could feed millions

New therapeutic approaches to treat autoimmune diseases using a metabolite

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics